65 completed, 21 unknown, 9 terminated, 6 recruiting. 64 Not applicable, 10 Phase 4, 7 Phase 2, 6 Phase 3, 2 Phase 1.
Follow Arthroplasty, Replacement, Hip: new trials by email Literature Review of Arthroplasty, Replacement, Hip trials Research Report on Arthroplasty, Replacement, Hip
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tau Pathology in the Brain After Hip or Knee Replacement Surgery Hip or Knee Arthroplasty Under Spinal Anesthesia - Postoperative Cognitive Dysfunction, Alzheimer Disease | Recruiting | Uppsala University Hospital | 30 | 2029-04-01 | 2026-10-15 | |
| A Study of the Effect of a Nurse Navigator Program on High Risk Patients Nurse Navigator Program - Patient Readmission, Arthroplasty, Replacement, Knee | Not applicable | Not yet recruiting | Mayo Clinic | 300 | 2027-01-01 | 2026-03-19 |
| Low-Volume Pericapsular Nerve Group (PENG) Block With Dexamethasone vs Standard-Volume PENG Block After Total Hip Arthroplasty Pericapsular nerve group (PENG) block, Bupivacaine, Dexamethasone - Pain, Postoperative, Muscle Weakness | Phase 4 | Recruiting | Ain Shams University | 60 | 2026-10-15 | 2026-10-16 |
| Early Mobilization and Postoperative Complications in Hip Arthroplast Early Mobilization Education, Routine Postoperative Care - Arthroplasty, Replacement, Hip, Patient Education | Not applicable | Not yet recruiting | Cyprus Aydin University | 60 | 2026-10-10 | 2026-10-09 |
| Multimodal Analgesic Regimen for Total Hip Arthroplasty: An Initiative to Minimize Postoperative Opioid Use Standard Multimodal Analgesic Regimen with Opioid Prescription, Opioid-Reduced Multimodal Analgesic Regimen with Printed Prescription - Arthroplasty, Replacement, Hip | Not applicable | Recruiting | Henry Ford Health System | 100 | 2026-07-20 | 2026-10-07 |
| Sleep Patterns After Total Joint Replacement Surgery Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Hip | Withdrawn | Henry Ford Health System | 2026-06-01 | 2026-08-11 | ||
| Analgesic Efficacy of Continuous SESP vs Continuous FICB After Hip Arthroplasty Continuous Sacral Erector Spinae Plane Block, Continuous Fascia Iliaca Compartment Block - Pain, Postoperative; Anesthesia, Regional, Arthroplasty, Replacement, Hip | Not applicable | Completed | Bach Mai Hospital | 60 | 2026-04-09 | 2026-09-01 |
| Development and Measurement of the Effects of a Digital Education Solution for Patients Undergoing Total Hip or Knee Arthroplasty Digital Preoperative Education with CHUVeduc@home, Standard Care Pathway - Arthroplasty Replacement, Knee, Arthroplasty, Replacement, Hip | Not applicable | Not yet recruiting | Haute Ecole de Santé Vaud | 160 | 2026-02-15 | 2026-01-15 |
| Role of Iliotibial Band Stiffness in Perceived Leg Length Discrepancy After Total Hip Arthroplasty Shear-Wave Elastography (Ultrasound) - Postoperative Evaluation, Arthroplasty, Replacement, Hip | Completed | Ankara Etlik City Hospital | 68 | 2026-01-14 | 2026-02-24 | |
| PENG Block + LIA For Endoprosthesis Surgery Pericapsular Nerve Group Blocks with Local Infiltration Analgesia, spinal anesthesia - Hip Fractures, Arthroplasty, Replacement, Hip | Not applicable | Recruiting | ASST Gaetano Pini-CTO | 100 | 2025-12-09 | 2026-09-22 |
| Associations Between Time to Reduction and Complications in Patients With Dislocated Total Hip Arthroplasty Time in minutes from admission to closed reduction - Closed Reduction, Arthroplasty, Replacement, Hip | Not yet recruiting | Nordsjaellands Hospital | 3700 | 2025-08-20 | 2025-08-20 | |
| Preoperative Fasting and the Gut Microbiome Before Hip Replacement Buchinger Fastenbox + intermittent fasting (20-day preoperative schedule) - Hip Osteoarthritis, Arthroplasty, Replacement, Hip | Not applicable | Recruiting | Charite University, Berlin, Germany | 130 | 2025-07-01 | 2026-06-22 |
| Phase IIa Trial of Oral SSS17 for Post-Arthroplasty Anemia SSS17 Capsule (6 Dose Levels), Placebo Drug - Postoperative Anemia, Arthroplasty, Replacement, Hip | Phase 2 | Not yet recruiting | Shenyang Sunshine Pharmaceutical Co., LTD. | 90 | 2025-07-01 | 2025-06-11 |
| Dimolegin® (60 mg) Given Once Daily in Patients Undergoing Total Hip or Knee Replacement Compared to Enoxaparin Sodium enoxaparin, Dimolegin, Dimolegin placebo - Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee | Phase 3 | Completed | Avexima Diol LLC | 215 | 2024-07-22 | 2026-01-16 |
| Testing Implementation of Total Joint Replacement Rehabilitation Quality Indicator Toolkits QI toolkit implementation - Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee | Not applicable | Unknown | University of British Columbia | 135 | 2024-01-01 | 2024-01-17 |
| Low Concentration Local Anesthesia Fascia Iliaca Block for Total Hip Arthroplasty Low Concentration Local Anesthetic Fascia Iliaca Compartment Block, High Concentration Local Anesthetic Fascia Iliaca Compartment Block - Arthroplasty, Replacement, Hip | Not applicable | Completed | University of Toronto | 60 | 2023-10-23 | 2026-05-13 |
| Study Measuring the Effects of Patient Data for Total Hip and Total Knee Arthroplasty Patients Using an APP Based Sensor for Home Exercise Performance Before and After Operation OrthoPath, Control - Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee | Withdrawn | Aesculap AG | 2023-06-01 | 2023-08-25 | ||
| Exploring Novel Diagnostic Tools for Periprosthetic Joint Infection Reporter Gene Assay, Flow Cytometry - Prosthesis-Related Infections, Arthroplasty, Replacement, Hip | Completed | Rijnstate Hospital | 60 | 2023-01-01 | 2025-08-08 | |
| MARS MRI in Revision THA With a Ceramic Femoral Head and Titanium Sleeve MARS MRI, Titanium Labs, Cobalt Labs - Arthroplasty, Replacement, Hip | Unknown | Colorado Joint Replacement | 55 | 2022-12-22 | 2023-01-17 | |
| TENS for Relief of Postoperative Pain in Orthopedic Patients transcutaneous electrical nerve stimulation (TENS), Sham transcutaneous electrical nerve stimulation (TENS) - Orthopedic Disorder, Post Operative Pain | Not applicable | Active not recruiting | Karolinska University Hospital | 30 | 2022-11-01 | 2024-10-22 |
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Pain, Postoperative (10) · Osteoarthritis, Hip (7) · Thrombosis (4) · Venous Thromboembolism (4) · Agnosia (3) · Thromboembolism (3) · Venous Thrombosis (3) · Anemia (2) · Hip Fractures (2) · Motor Activity (2) · Osteoarthritis (2) · Pain (2) · Postoperative Complications (2) · Alcoholism (1) · Alzheimer Disease (1)
Pathological Conditions, Signs and Symptoms (25) · Pathologic Processes (20) · Neurologic Manifestations (15) · Signs and Symptoms (15) · Postoperative Complications (12) · Cardiovascular Diseases (11) · Musculoskeletal Diseases (10) · Pain (10) · Arthritis (9) · Joint Diseases (9) · Rheumatic Diseases (9) · Vascular Diseases (9) · Nervous System Diseases (8) · Embolism and Thrombosis (7) · Osteoarthritis (7)
Ropivacaine (6) · Sodium Chloride (4) · Tranexamic Acid (4) · Arthroplasty, Replacement, Hip (3) · Enoxaparin (3) · enoxaparin sodium (3) · Control Groups (2) · Epinephrine (2) · Morphine (2) · edoxaban (2) · (+-)-(1'R*,2'S*,6'R*)-(2-hydroxy-4,6-dimethoxyphenyl)(3'-methyl-2'-(3''-methylbut-2''-enyl)-6-phenylcyclohex-3'-enyl)methanone (1) · Administration, Topical (1) · Airway Management (1) · Alendronate (1) · Anesthesia, Spinal (1)
Stryker Orthopaedics (15) · Seoul National University Bundang Hospital (3) · Aesculap AG (2) · Alberta Bone and Joint Health Institute (2) · Boehringer Ingelheim (2) · Bornholms Regionskommune (2) · Daniel Hägi-Pedersen (2) · Haute Ecole de Santé Vaud (2) · Henry Ford Health System (2) · Hospital for Special Surgery, New York (2) · Istituto Ortopedico Rizzoli (2) · Ottawa Hospital Research Institute (2) · The Cleveland Clinic (2) · University of Aarhus (2) · VA Office of Research and Development (2)
United States (34) · Denmark (14) · Canada (13) · Germany (7) · Italy (7) · Netherlands (7) · Sweden (6) · United Kingdom (6) · France (5) · Norway (4) · Spain (4) · Austria (3) · Belgium (3) · Japan (3) · Russia (3)
James D'Antonio, MD (4) · Benjamin Bierbaum, MD (3) · Kyung-Hoi Koo, professor (3) · William Capello, MD (3) · Amit Atrey, MD (2) · Arthur Malkani, MD (2) · Carlos A Higuera, MD (2) · Carol A Mancuso, MD (2) · Daniel Ward, MD (2) · Geoffrey Westrich, MD (2) · John Wright, MD (2) · Joseph Nessler, M.D. (2) · Kirby Hitt, MD (2) · Michael Charters, MD (2)
PMID 12873949, PMID 12934742, PMID 15744696, PMID 16885182, PMID 17394987, PMID 17413915, PMID 17869635, PMID 18196427, PMID 19216667, PMID 19258967, PMID 19455368, PMID 19455501, PMID 19536029, PMID 19586079, PMID 19632618, PMID 19715815, PMID 19723982, PMID 20334992, PMID 20510800, PMID 20562609, PMID 21733697, PMID 21999623, PMID 22709460, PMID 22796513, PMID 22810157, PMID 22995531, PMID 23028549, PMID 24136153, PMID 24522223, PMID 25047458, PMID 25058504, PMID 25208233, PMID 2589650, PMID 26578849, PMID 27043725, PMID 29368313, PMID 31183463, PMID 31192911, PMID 31416443, PMID 31448107, PMID 31665548, PMID 32698642, PMID 32790073, PMID 33581971, PMID 34316356, PMID 35757239, PMID 35964101, PMID 36085337, PMID 36635747, PMID 38373934
2004 (1), 2008 (1), 2014 (1)