35 withdrawn. 35 Phase 1, 18 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 35 | Withdrawn 35 |
| Phase 2 | 18 | Withdrawn 18 |
Follow Arthritis: new trials by email Literature Review of Arthritis trials Research Report on Arthritis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cannabichromene Safety in Rheumatoid Arthritis Cannabichromene - Arthritis, Rheumatoid | Phase 1 / Phase 2 | Withdrawn | Crystal Lederhos Smith | 2028-07-15 | 2026-09-23 | |
| Evaluation of Superiority of Valsartan+Celecoxib+Metformin Over Metformin Alone in Type 2 Diabetes Patients Metformin, Val, Cel and Met XR Low, Val, Cel and Met XR High - Type 2 Diabetes, High Blood Pressure | Phase 1 / Phase 2 | Withdrawn | ARKAY Therapeutics | 2026-12-10 | 2026-07-16 | |
| A Study Evaluating the Safety, Tolerability, and Activity of ICM-203 in Subjects With Knee Osteoarthritis. ICM-203 - Osteoarthritis, Knee | Phase 1 / Phase 2 | Withdrawn | ICM Co. Ltd. | 2026-11-15 | 2026-09-08 | |
| Pharmacokinetics and Pharmacodynamics of Biologic Drugs in Obese Patients With Arthritis Etanercept Optimal dosing - Juvenile Idiopathic Arthritis, Rheumatoid Arthritis | Phase 1 | Withdrawn | Duke University | 2026-07-01 | 2025-09-25 | |
| Autologous CD19/BCMA Dual-Target CAR-T for Relapsed/Refractory Autoimmune Diseases Autologous CD19-BCMA Dual-Target CAR T-Cell Therapy - Relapsed/Refractory Systemic Lupus Erythematosus, Relapsed/Refractory Systemic Sclerosis | Phase 1 | Withdrawn | Beijing Boren Hospital | 2025-11-06 | 2026-10-15 | |
| Safety and Efficacy of Abatacept for Treating Chronic Cytopenia in Cytotoxic T-Lymphocyte Antigen 4 (CTLA4) Haploinsufficiency abatacept, Placebo - CTLA4 Haploinsufficency, Chronic Cytopenia | Phase 1 / Phase 2 | Withdrawn | National Institute of Allergy and Infectious Diseases (NIAID) | 2023-11-30 | 2023-12-04 | |
| Platelet-Rich Plasma and the Effects of NSAIDs on Pain and Functional Scores in Knee Osteoarthritis Ibuprofen and PRP, Acetaminophen and PRP, Placebo and PRP - Osteoarthritis of the Knee, Degenerative Osteoarthritis | Phase 1 / Phase 2 | Withdrawn | QC Kinetix LLC | 2023-11-01 | 2024-10-09 | |
| Targeting Senescence to Reduce Osteoarthritis Pain and cartilagE Breakdown (ROPE) High-dose/short-duration Fisetin, Low-dose/sustained-duration Fisetin, Oral placebo capsule - Osteoarthritis, Knee | Phase 1 / Phase 2 | Withdrawn | Austin V Stone | 2023-06-01 | 2022-07-29 | |
| Safety and Preliminary Signs of Efficacy of F8IL10 for Intra-articular Treatment F8IL10 - Rheumatoid Arthritis | Phase 1 | Withdrawn | Philogen S.p.A. | 2023-03-31 | 2025-12-02 | |
| A Study in Healthy Japanese Participants to Evaluate the Safety and Pharmacokinetics of Otilimab Otilimab - Arthritis, Rheumatoid | Phase 1 | Withdrawn | GlaxoSmithKline | 2023-02-08 | 2023-01-26 | |
| Preliminary Safety and Efficacy of XT-150 in Facet Joint Osteoarthritis XT-150 - Osteoarthritis, Spine | Phase 1 / Phase 2 | Withdrawn | Xalud Therapeutics, Inc. | 2021-10-01 | 2022-03-17 | |
| Study of AlloGen® Liquid Intra-articular Injection for Knee Osteoarthritis AlloGen Liquid, Placebo - Osteoarthritis, Knee | Phase 1 | Withdrawn | VIVEX Biologics, Inc. | 2021-06-01 | 2021-07-08 | |
| Clinical Trial to Assess Safety and Immunogenicity of a Synthetic Vaccine Against Streptococcus Pyogenes Streptococcus pyogenes vaccine (50 µg), Streptococcus pyogenes vaccine (100 µg), Streptococcus pyogenes vaccine (200 µg) - Rheumatic Fever | Phase 1 | Withdrawn | Butantan Institute | 2021-05-01 | 2021-02-04 | |
| The Phosphodiesterase 3 Inhibitor Cilostazol as an Adjunct to Conventional Therapy in Patients With Osteoarthritis Cilostazol 50 MG, Placebo - Osteoarthritis | Phase 1 / Phase 2 | Withdrawn | Sadat City University | 2021-03-01 | 2025-07-14 | |
| The GRK2 Inhibitor Paroxetine as a Novel Adjunct to Conventional Therapy in Rheumatoid Arthritis Patients Paroxetine, Placebo - Rheumatoid Arthritis | Phase 1 / Phase 2 | Withdrawn | Sadat City University | 2021-02-01 | 2025-07-14 | |
| Denosumab for Glucocorticoid-treated Children With Rheumatic Disorders denosumab - Osteoporosis, Juvenile Rheumatoid Arthritis | Phase 1 / Phase 2 | Withdrawn | Indiana University | 2019-08-01 | 2019-12-06 | |
| Safety of Allogeneic Bone Marrow Derived Mesenchymal Stem Cells in Subjects With Osteoarthritis Human allogeneic mesenchymal bone marrow derived stem cells - Knee Osteoarthritis | Phase 1 | Withdrawn | Clinica Santa Clarita, Mexico | 2019-08-01 | 2020-07-15 | |
| Very Small Embryonic-like Stem Cells for Knee Osteoarthritis very small embryonic-like stem cell - Stem Cell Transplant Complications, Knee Osteoarthritis | Phase 1 / Phase 2 | Withdrawn | Fuda Cancer Hospital, Guangzhou | 2019-07-05 | 2020-10-19 | |
| A Study to Evaluate the Safety, Mode of Action and Clinical Efficacy of GSK3050002 in Subjects With Psoriatic Arthritis GSK3050002, Placebo - Autoimmune Diseases | Phase 1 | Withdrawn | GlaxoSmithKline | 2018-06-01 | 2018-08-31 | |
| Pharmacokinetics and Dosimetry of Tc 99m Tilmanocept Following a Single Intravenous Dose Administration in Male and Female Subjects Diagnosed With Rheumatoid Arthritis (RA) Tilmanocept - Arthritis, Rheumatoid | Phase 1 | Withdrawn | Navidea Biopharmaceuticals | 2017-09-01 | 2018-10-09 |
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Arthritis, Rheumatoid (12) · Osteoarthritis (11) · Osteoarthritis, Knee (10) · Arthritis, Juvenile (3) · Sjogren's Syndrome (3) · Obesity (2) · Pain (2) · Anemia, Hemolytic, Autoimmune (1) · Arthritis, Psoriatic (1) · Autoimmune Diseases (1) · Bronchiolitis Obliterans Syndrome (1) · Cough (1) · Dermatomyositis (1) · Diabetes Mellitus (1)
Musculoskeletal Diseases (35) · Joint Diseases (34) · Rheumatic Diseases (32) · Immune System Diseases (18) · Skin and Connective Tissue Diseases (18) · Connective Tissue Diseases (17) · Autoimmune Diseases (16) · Pathological Conditions, Signs and Symptoms (5) · Signs and Symptoms (5) · Osteoarthritis (4) · Arthritis, Rheumatoid (3) · Bone Diseases (3) · Dry Eye Syndromes (3) · Eye Diseases (3)
Abatacept (2) · AZD9056 (1) · Acetaminophen (1) · Arthroplasty, Replacement, Hip (1) · Carboxylesterase (1) · Celecoxib (1) · Cilostazol (1) · Citrates (1) · Citric Acid (1) · Control Groups (1) · Denosumab (1) · GSK3050002 (1) · Ibuprofen (1) · Metformin (1) · Methotrexate (1)
Translational Biosciences (4) · GlaxoSmithKline (2) · Sadat City University (2) · ARKAY Therapeutics (1) · AstraZeneca (1) · Austin V Stone (1) · Beijing Boren Hospital (1) · Bristol-Myers Squibb (1) · Butantan Institute (1) · Clinica Santa Clarita, Mexico (1) · Crystal Lederhos Smith (1) · Duke University (1) · Fuda Cancer Hospital, Guangzhou (1) · ICM Co. Ltd. (1) · Imperial College London (1)
United States (12) · Panama (4) · China (2) · Egypt (2) · Australia (1) · France (1) · Israel (1) · Mexico (1) · South Korea (1) · United Kingdom (1)
Jorge Paz-Rodriguez, MD (2) · Alison Heald, MD (1) · Austin Stone, MD, PhD (1) · Brian Cole, MD (1) · Chul-Won Ha, M.D. (1) · Crystal L Smith, PhD (1) · Dennis W Miller, MD (1) · Erik Imel, MD (1) · Gulbu Uzel, M.D. (1) · Jorge Paz-Rodriguez, M.D. (1) · Kenneth P Barnes, MD, MSc. (1) · Lucinda Baker, Ph.D (1)
K23AR075874 (1)