2 active not recruiting, 1 completed, 1 not yet recruiting, 1 recruiting. 4 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Active not recruiting 2, Completed 1, Not yet recruiting 1 |
| Phase 2 | 4 | Active not recruiting 2, Completed 1, Recruiting 1 |
Follow atibuclimab: new trials by email Literature Review of atibuclimab trials Research Report on atibuclimab
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pilot and Feasibility Study of Anti-CD14 for the Treatment of Knee Osteoarthritis Atibuclimab, saline placebo - Knee Osteoarthritis (Knee OA) | Phase 1 | Not yet recruiting | VA Office of Research and Development | 40 | 2027-01-01 | 2026-07-15 |
| Anti-CD14 Treatment With IC14 in Hospitalized ARDS Patients Atibuclimab, Placebo - Acute Respiratory Distress Syndrome, Adult Respiratory Distress Syndrome | Phase 2 | Recruiting | Implicit Bioscience | 56 | 2026-06-17 | 2026-07-29 |
| Pilot Study of IC14 (Atibuclimab), an Anti-CD14 Monoclonal Antibody, to Treat STEMI Atibuclimab (IC14), 20 mg/kg intravenously, once, Placebo, 150 mL intravenously, once - STEMI, STEMI (ST Elevation MI) | Phase 1 / Phase 2 | Active not recruiting | Implicit Bioscience | 10 | 2025-02-06 | 2026-03-27 |
| IC14 for Treatment of Acute Decompensated Heart Failure Atibuclimab (IC14) - Acute Decompensated Heart Failure | Phase 1 / Phase 2 | Active not recruiting | Implicit Bioscience | 10 | 2024-10-17 | 2026-03-27 |
| IC14 (Atibuclimab) in Arrhythmogenic Cardiomyopathy IC14 - Arrhythmogenic Right Ventricular Dysplasia, Arrhythmogenic Left Ventricular Cardiomyopathy | Phase 1 / Phase 2 | Completed | Implicit Bioscience | 1 | 2024-03-29 | 2026-04-22 |
Acute Lung Injury (1) · Arrhythmias, Cardiac (1) · Arrhythmogenic Right Ventricular Dysplasia (1) · Arrhythmogenic Right Ventricular Dysplasia, Familial, 1 (1) · Heart Failure (1) · Osteoarthritis, Knee (1) · Respiratory Distress Syndrome (1) · ST Elevation Myocardial Infarction (1)
Implicit Bioscience (4) · VA Office of Research and Development (1)
United States (5)
Antonio Abbate, MD (1) · Antonio Abbate, MD, PhD (1) · Jan Agosti, MD (1) · Joshua F. Baker, MD MSCE (1) · Linzee Mabrey, MD, MsC (1) · Marc Sintek, MD (1)