19 completed, 3 terminated, 2 recruiting, 1 unknown. 23 Not applicable, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 23 | Completed 18, Terminated 3, Recruiting 1, Unknown 1 |
| Phase 4 | 2 | Completed 1, Recruiting 1 |
Follow Arachnophobia: new trials by email Literature Review of Arachnophobia trials Research Report on Arachnophobia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| In Vivo Exposure vs. Videochat-Based Vicarious Exposure In Vivo Exposure Training (IVET), Vicarious Exposure Training (VicET) - Anxiety, Anxiety Disorders | Not applicable | Recruiting | Ruhr University of Bochum | 72 | 2026-02-26 | 2026-03-02 |
| The Effects of Propranolol and Hydrocortisone on Military-Relevant Performance Outcomes Propranolol, Hydrocortisone, Placebo (oral) - Fear of Spiders, Acute Stress Reaction | Phase 4 | Recruiting | Walter Reed Army Institute of Research (WRAIR) | 88 | 2025-05-27 | 2026-05-13 |
| The Effect of Time on Generalization of Exposure-based Benefit Exposure - One Week Follow-up Assessment, Six Weeks Follow-up Assessment | Not applicable | Completed | Ruhr University of Bochum | 59 | 2024-07-08 | 2026-01-30 |
| Feasibility of an Online Modeled Exposure in Spider Fearful Individuals online psychoeducation video + modeled exposure, live psychoeducation video + modeled exposure, group exposure - Spider Fear, Arachnophobia | Not applicable | Completed | Philipps University Marburg | 78 | 2023-12-11 | 2025-10-02 |
| Telemedicine-Based Virtual Reality Clinic for the Treatment of Phobias Telemedicine Exposure Therapy Using Photos and Videos, Telemedicine-Based Virtual Reality Exposure Therapy - Arachnophobia, Cynophobia | Not applicable | Completed | University of South Florida | 54 | 2023-10-25 | 2026-05-18 |
| Optimizing Exposure Using Occasional Aversive Imagery in Spider Fearful Individuals occasional aversive imagination, Exposure - Spider Fear, Arachnophobia | Not applicable | Completed | Philipps University Marburg | 67 | 2022-06-15 | 2026-01-09 |
| The Neural Mechanisms of Imaginal Extinction Threat conditioning, Imaginal extinction - Fear of Spiders | Not applicable | Completed | Uppsala University | 87 | 2022-04-07 | 2024-08-26 |
| Neural Mechanisms of Imaginal and in Vivo Exposure Imaginal exposure, Exposure, Approach-avoidance conflict - Fear of Spiders | Not applicable | Completed | Uppsala University | 87 | 2022-04-07 | 2024-08-26 |
| Gamification in the Treatment of Spider Phobia 7-day exposure therapy via self-developed app according to (Haberkamp et al., submitted), Therapist-guided one-session online exposure therapy according to (Öst, 1989) - Spider Phobia | Not applicable | Completed | Anke Haberkamp | 90 | 2020-07-01 | 2024-11-08 |
| Efficacy of a Gamified Augmented Reality Exposure-based Application in Subjects With Fear of Spiders AR app - Fear of Spiders | Not applicable | Completed | Prof. Dominique de Quervain, MD | 60 | 2019-10-07 | 2019-12-20 |
| TMS and Exposure Therapy Intermittent Theta Burst Stimulation (iTBS), Ventromedial Prefrontal Cortex (vmPFC), Intermittent Theta Burst Stimulation (iTBS), vertex - Arachnophobia, Phobia | Not applicable | Terminated | University of California, Los Angeles | 22 | 2019-08-19 | 2021-04-01 |
| Generalized Fear Extinction to Untreated Fear Stimuli in Specific Phobias After Exposure Exposure - Fear of Spiders, Fear of Heights | Not applicable | Completed | Ruhr University of Bochum | 50 | 2019-06-06 | 2023-03-30 |
| Use of Safety Behaviors in Exposure Therapy for Arachnophobia Exposure with faded safety behaviors, Exposure without safety behaviors, Exposure with unfaded safety behaviors - Specific Phobia, Arachnophobia | Not applicable | Completed | University of Nevada, Reno | 59 | 2019-02-28 | 2021-10-18 |
| Efficacy of Targeted Memory Reactivation for Enhancing Exposure Therapy Experimental Scent, Control Scent, No-Scent Control - Claustrophobia, Obsessive-Compulsive Disorder | Not applicable | Completed | University of Texas at Austin | 158 | 2019-01-29 | 2020-12-11 |
| Optimizing Exposure Therapy With Mental Rehearsal Mental Rehearsal, Exposure - Anxiety Disorders, Arachnophobia | Not applicable | Completed | University of California, Los Angeles | 72 | 2018-10-23 | 2019-12-18 |
| Bringing Exposure Therapy to Real-Life Context With Augmented Reality Augmented reality exposure therapy - Phobias Snakes, Phobias Spiders | Not applicable | Terminated | Wayne State University | 25 | 2018-08-30 | 2022-04-19 |
| Effects of Stress on Exposure Therapy Cold water condition, Warm water condition - Specific Phobia | Not applicable | Completed | Ruhr University of Bochum | 48 | 2018-04-20 | 2019-09-11 |
| One-session Treatment for Spider Fears CR-EXP, EXP-CR, Stress Management - Spider Phobia | Not applicable | Completed | University of North Carolina, Chapel Hill | 51 | 2018-01-20 | 2021-03-08 |
| The Role of Treatment Expectation in Exposure Training With Spider Fearful Participants positive treatment expectations, neutral treatment expectations - Phobic Disorders | Not applicable | Completed | University Hospital, Basel, Switzerland | 70 | 2017-05-18 | 2018-03-21 |
| tDCS-Augmented Exposure Therapy for Pathological Fear Transcranial Direct Current Stimulation (tDCS), In vivo exposure therapy - Specific Phobias | Not applicable | Completed | University of Texas at Austin | 49 | 2017-01-01 | 2020-12-08 |
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Phobia, Specific (8) · Anxiety Disorders (7) · Phobic Disorders (3) · Zoophobia (3) · Acrophobia (2) · Alzheimer Disease (1) · Claustrophobia (1) · Mysophobia (1) · Obsessive-Compulsive Disorder (1) · Stress Disorders, Post-Traumatic (1) · Stress Disorders, Traumatic, Acute (1)
Mental Disorders (12) · Anxiety Disorders (4) · Stress Disorders, Traumatic (2) · Trauma and Stressor Related Disorders (2) · Brain Diseases (1) · Central Nervous System Diseases (1) · Dementia (1) · Nervous System Diseases (1) · Neurocognitive Disorders (1) · Neurodegenerative Diseases (1) · Phobic Disorders (1) · Tauopathies (1)
Implosive Therapy (2) · Propranolol (2) · Hydrocortisone (1) · Mifepristone (1) · Oxytocin (1) · Transcranial Direct Current Stimulation (1) · Videotape Recording (1) · Virtual Reality Exposure Therapy (1)
Ruhr University of Bochum (5) · University of Texas at Austin (4) · Philipps University Marburg (2) · University of California, Los Angeles (2) · Uppsala University (2) · Anke Haberkamp (1) · Massachusetts General Hospital (1) · Prof. Dominique de Quervain, MD (1) · University Hospital, Basel, Switzerland (1) · University of Nevada, Reno (1) · University of North Carolina, Chapel Hill (1) · University of Regensburg (1) · University of South Florida (1) · Walter Reed Army Institute of Research (WRAIR) (1) · Wayne State University (1)
United States (12) · Germany (7) · Sweden (2) · Switzerland (2)
Armin Zlomuzica, PhD (2) · Adam R. Cobb, Ph.D. (1) · Anastasia L McGlade, MA (1) · Anke Haberkamp, PhD (1) · Arash Javanbakht, MD (1) · Armin Zlomuzica, Dr. (1) · Armin Zlomuzica, Prof. Dr. (1) · Brian E Bunnell, PhD (1) · Christiane A. Melzig, PhD (1) · Christoph Benke, PhD (1) · Dominique de Quervain, Prof. (1) · Dorothee Scheuermann, M.Sc. (1) · Jana Gessner, M.Sc. (1) · Jens Gaab, Prof. Dr. (1)
PMID 25224026, PMID 27314560, PMID 33308073, PMID 40209221, PMID 42267056, PMID 42296397
2018 (1), R43MH129065 (1)