11 completed, 7 terminated, 6 unknown, 2 not yet recruiting. 29 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 29 | Completed 11, Terminated 7, Unknown 6, Not yet recruiting 2, Recruiting 2, Withdrawn 1 |
Follow Aortic Aneurysm: new trials by email Literature Review of Aortic Aneurysm trials Research Report on Aortic Aneurysm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Remimazolam on Postoperative Cognitive Dysfunction and Neuroinflammatory Biomarkers in Patients Undergoing Aortic Arch Surgery Remimazolam Besylate, propofol - Aortic Aneurysm of the Proximal Arch, Aortic Aneurysms Arch | Phase 4 | Not yet recruiting | Seoul National University Hospital | 80 | 2026-11-01 | 2026-10-29 |
| Effect of Remimazolam Versus Propofol Total Intravenous Anesthesia on Intraoperative Hemodynamic Stability in Patients Undergoing Thoracic or Abdominal Endovascular Aortic Repair Remimazolam Besylate, propofol - Aortic Aneurysm, Thoracoabdominal, Aortic Aneurysm, Abdominal | Phase 4 | Recruiting | Seoul National University Hospital | 44 | 2026-10-01 | 2026-10-29 |
| Life-saving Treatment With Dry-plasma for Massive Bleeding in an Pre-hospital Setting Dry plasma - Bleeding, Aortic Rupture | Phase 4 | Not yet recruiting | Vastra Gotaland Region | 650 | 2026-01-01 | 2025-09-17 |
| Effect of Dexamethason on Postimplantation Syndrome After EVAR Dexamethasone, Placebo - Aneurysm Abdominal, Endovascular Aneurysm Repair | Phase 4 | Unknown | Centro Hospitalar de Lisboa Central | 158 | 2023-11-01 | 2023-09-21 |
| Liposomal Bupivacaine/Bupivacaine in Rectus Sheath Blocks Versus Ropivacaine in Rectus Sheath Blocks And Catheters Liposomal bupivacaine, Ropivacaine, Bupivacain - Aortic Aneurysm, Abdominal, Abdominal Aortic Occlusion | Phase 4 | Recruiting | Hartford Hospital | 14 | 2023-10-18 | 2025-09-03 |
| ACT Guided Heparinization During Open Abdominal Aortic Aneurysm Repair. ACT guided heparinization, 5 000 IU of heparin - Abdominal Aortic Aneurysm, Surgery | Phase 4 | Terminated | Dijklander Ziekenhuis | 294 | 2020-03-02 | 2025-02-06 |
| Impact of Intra- and Postoperative Continuous Infusion of Lidocaine on Analgesia in Vascular Anaesthesia lidocaine 10mg/ml, Placebo, Metamizole - Abdominal Aorta Aneurysm, Abdominal Aorta Atheroma | Phase 4 | Completed | Łukasz Krzych | 87 | 2019-01-29 | 2022-12-21 |
| Preoperative Intravenous Ferric Carboxymaltose and Placebo in the Treatment of Patients Undergoing Cardiac Surgery Ferric carboxymaltose, Physiological saline - Coronary Artery Disease, Postoperative Complications | Phase 4 | Unknown | Turku University Hospital | 210 | 2018-10-02 | 2021-04-20 |
| Predictors of AAA Expansion and/or Rupture Assess AAA rupture risk by PET-CTA scans, 18F-fludeoxyglucose (FDG), 11C-PBR28 - Abdominal Aortic Aneurysm (AAA) | Phase 4 | Terminated | Washington University School of Medicine | 2 | 2017-08-01 | 2021-07-09 |
| Eplerenone in the Management of Abdominal Aortic Aneurysms Eplerenone - Aortic Aneurysm, Abdominal | Phase 4 | Unknown | Bayside Health | 172 | 2015-05-01 | 2016-01-15 |
| CUstodiol Versus RInger: whaT Is the Best Agent? Custodiol, Enriched Ringer's lactate solution - Thoracoabdominal Aortic Aneurysms | Phase 4 | Completed | Scientific Institute San Raffaele | 90 | 2015-02-01 | 2019-05-23 |
| Vasculopathic Injury and Plasma as Endothelial Rescue - OCTAplas Trial (EudraCT no. 2014-000452-28) OctaplasLG®, Fresh frozen plasma - Aortic Aneurysm, Thoracic, Endothelial Dysfunction | Phase 4 | Completed | Copenhagen University Hospital, Rigshospitalet | 44 | 2014-11-01 | 2016-12-20 |
| Bloodtranfusions After Aortic Surgery Haemocomplettan P, Placebo - Hemorrhage, Thoracic Aneurysm | Phase 4 | Terminated | St. Antonius Hospital | 27 | 2014-08-01 | 2019-05-10 |
| Effectiveness of Acetazolamide in Reducing Paralysis of the Leg in Patients Undergoing Aortic Aneurysm Surgery Surgery Acetazolamide - Thoracic Aneurysm | Phase 4 | Unknown | Liverpool Heart and Chest Hospital NHS Foundation Trust | 100 | 2014-07-01 | 2014-12-31 |
| Thoracoabdominal Arortic CTA Study Isovue - Thoracic Aortic Aneurysm | Phase 4 | Completed | Duke University | 150 | 2014-01-01 | 2017-04-18 |
| Study of the Effectiveness of Telmisartan in Slowing the Progression of Abdominal Aortic Aneurysms Telmisartan, Placebo - Abdominal Aortic Aneurysm | Phase 4 | Completed | Palo Alto Veterans Institute for Research | 22 | 2012-09-19 | 2020-05-26 |
| TAP-Block in Abdominal Aortic Surgery Ropivacaine, Placebo - Aortic Aneurysm, Abdominal | Phase 4 | Completed | Centre Hospitalier Universitaire Dijon | 50 | 2011-09-05 | 2018-09-05 |
| Long-term Benefit of Aortic Stent-graft in Patients With Distal Aortic Dissection Aortic stent-graft - Aortic Dissection, Aortic Aneurysm | Phase 4 | Terminated | Asan Medical Center | 7 | 2011-01-01 | 2015-01-14 |
| ATLANTIS:Extensive Type A Dissections and Thoracic/ Thoraco-Abdominal Aneurysms Repair With LupiAe Hybrid TechNique lupiae technique - Aortic Aneurysm | Phase 4 | Withdrawn | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 120 | 2010-06-01 | 2011-06-28 |
| A Safety and Efficacy Study of Blood Pressure Control in Acute Aortic Emergencies - A Pilot Study (PROMPT) clevidipine. - Aortic Aneurysm, Aortic Disease | Phase 4 | Terminated | Asma Zainab, M.D. | 5 | 2009-11-01 | 2018-08-27 |
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Aortic Aneurysm, Abdominal (14) · Aortic Aneurysm, Thoracic (7) · Aortic Aneurysm, Thoracoabdominal (4) · Aortic Dissection (3) · Agnosia (2) · Aortic Diseases (2) · Hemorrhage (2) · Aneurysm, Aortic Arch (1) · Aortic Rupture (1) · Aortic Valve Stenosis (1) · Coronary Artery Disease (1) · Emergence Delirium (1) · Emergencies (1) · Gastrointestinal Hemorrhage (1)
Aneurysm (29) · Cardiovascular Diseases (29) · Vascular Diseases (29) · Aortic Diseases (27) · Pathological Conditions, Signs and Symptoms (9) · Pathologic Processes (7) · Nervous System Diseases (4) · Neurologic Manifestations (4) · Signs and Symptoms (4) · Acute Aortic Syndrome (3) · Aortic Aneurysm, Abdominal (3) · Dissection, Blood Vessel (3) · Neurobehavioral Manifestations (3) · Arterial Occlusive Diseases (2)
Propofol (2) · Ropivacaine (2) · Acetazolamide (1) · Atorvastatin (1) · Bupivacaine (1) · Dexamethasone (1) · Dexmedetomidine (1) · Dipyrone (1) · Endovascular Aneurysm Repair (1) · Eplerenone (1) · Fluorodeoxyglucose F18 (1) · Immunonutrition Diet (1) · Iopamidol (1) · Lidocaine (1) · Mass Screening (1)
Seoul National University Hospital (2) · St. Antonius Hospital (2) · Stanford University (2) · Asan Medical Center (1) · Asma Zainab, M.D. (1) · Bayside Health (1) · Central Jutland Regional Hospital (1) · Centre Hospitalier Universitaire Dijon (1) · Centro Hospitalar de Lisboa Central (1) · Copenhagen University Hospital, Rigshospitalet (1) · Dijklander Ziekenhuis (1) · Duke University (1) · Hartford Hospital (1) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (1) · Liverpool Heart and Chest Hospital NHS Foundation Trust (1)
United States (9) · Netherlands (4) · Italy (3) · South Korea (3) · United Kingdom (3) · Denmark (2) · France (2) · Germany (2) · Poland (2) · Australia (1) · Czechia (1) · Finland (1) · Israel (1) · Spain (1)
Asma Zainab, MD (1) · Christopher K Zarins MD (1) · Christopher K Zarins, MD (1) · Eric PA van Dongen, phD (1) · Faisal Masud, MD (1) · Frank A. Lederle, MD (1) · Ian C Chetter, MBChB, FRCS (1) · Jakob Stensballe, MD, PhD (1) · Jason T Lee, MD (1) · Jason T. Lee (1) · Jes S. Lindholt, M.D.,Ph.D. (1) · Kevin Finkel, MD (1) · Leah Isles, MBBS (1)
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