37 completed, 7 terminated, 1 unknown, 1 withdrawn. 46 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 46 | Completed 37, Terminated 7, Unknown 1, Withdrawn 1 |
Follow Alcohol Dependence: new trials by email Literature Review of Alcohol Dependence trials Research Report on Alcohol Dependence
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Assessment of Valproate on Ethanol Withdrawal Valproate, Lorazepam - Alcohol Dependence, Alcohol Withdrawal Syndrome | Phase 4 | Terminated | CAMC Health System | 3 | 2017-07-11 | 2026-08-18 |
| Treatment for Alcohol Dependence With Gabapentin Gabapentin 2g/day divided in two doses for 24 weeks, Placebo 2g/day divided in two doses for 24 weeks - Alcohol Dependence | Phase 4 | Terminated | Dayanand Medical College and Hospital | 25 | 2016-06-01 | 2020-02-13 |
| Alcohol Disorder hOsPital Treatment Trial Oral naltrexone (PO-NTX), Extended-release injectable naltrexone (XR-NTX) - Heavy Drinking, Alcohol Dependence | Phase 4 | Completed | Boston University | 248 | 2016-06-01 | 2021-06-29 |
| Extended-release Naltrexone and Care Management for Alcohol Dependent Frequent Emergency Department Users XR-NTX+CM (Extended-Release Naltrexone plus Care Management) - Alcohol Dependence, Alcohol Use Disorder | Phase 4 | Completed | NYU Langone Health | 50 | 2015-07-01 | 2022-05-11 |
| Treatment of Patients Suffering of Alcohol Dependence and Impaired Liver Function With Selincro® As-needed Use nalmefene - Alcohol Dependence | Phase 4 | Completed | H. Lundbeck A/S | 45 | 2014-09-01 | 2016-12-14 |
| Study of 18 mg Selincro® As-needed Use, in the Treatment of Patients With Alcohol Dependence in Primary Care Selincro® 18 mg with continuous psychosocial support: Cohort A, Initial psychosocial support: Cohort B - Alcohol Dependence | Phase 4 | Terminated | H. Lundbeck A/S | 378 | 2014-08-01 | 2017-02-28 |
| Extended-Release vs. Oral Naltrexone Alcohol Treatment in Primary Care XR-NTX (Extended-Release Naltrexone), Oral Naltrexone (O-NTX) - Alcohol Dependence | Phase 4 | Completed | NYU Langone Health | 237 | 2014-06-01 | 2020-06-16 |
| Citicoline for Alcohol Dependence Placebo, Citicoline - Alcohol Dependence | Phase 4 | Completed | University of Texas Southwestern Medical Center | 62 | 2014-04-01 | 2018-07-24 |
| A Controlled Trial of Topiramate Treatment for Alcohol Dependence in Veterans With PTSD Topiramate, placebo, Medical Management - Alcohol Dependence, Posttraumatic Stress Disorder (PTSD) | Phase 4 | Completed | University of California, San Francisco | 151 | 2013-02-01 | 2021-06-21 |
| Dutasteride Treatment for the Reduction of Heavy Drinking in Men Dutasteride, sugar pill - Alcoholism, Alcohol Abuse | Phase 4 | Completed | UConn Health | 189 | 2013-01-01 | 2019-04-26 |
| Pharmacotherapy for Alcohol Dependence in Convicted Drinking Drivers Naltrexone, Control - Alcohol Dependence | Phase 4 | Terminated | Centre for Addiction and Mental Health | 2 | 2012-08-01 | 2014-04-02 |
| Dutasteride for the Reduction of Alcohol Use in Male Drinkers Dutasteride, Placebo - Alcoholism, Alcohol Abuse | Phase 4 | Completed | UConn Health | 47 | 2011-01-01 | 2017-03-20 |
| Pilot Study of Depot NTX in Homeless Veterans Depot naltrexone, Oral Naltrexone - Alcohol Dependence | Phase 4 | Terminated | US Department of Veterans Affairs | 7 | 2010-08-01 | 2014-07-17 |
| Topiramate for Hospitalized Patients With Alcoholism: a 12-week Study Topiramate - Alcohol Dependence | Phase 4 | Unknown | Chiang Mai University | 150 | 2010-07-01 | 2011-08-15 |
| Treatment of Alcohol Dependence and Comorbid Bipolar Disorder Lamotrigine, Placebo - Alcohol Dependence, Bipolar Disorder | Phase 4 | Completed | Medical University of South Carolina | 43 | 2010-02-01 | 2019-01-09 |
| Identifying Multiple Mechanisms of Change in Alcoholism Treatment Cognitive behavioral therapy for alcohol dependence - Alcohol Dependence | Phase 4 | Completed | State University of New York at Buffalo | 61 | 2010-01-01 | 2014-12-03 |
| Baclofen as Add-On to Standard Treatment of Alcohol- Dependent Patients Baclofen, Control group - Alcohol Dependence | Phase 4 | Completed | Sha'ar Menashe Mental Health Center | 75 | 2010-01-01 | 2017-01-27 |
| Disulfiram Combined With Lorazepam for Alcohol Dependence and Anxiety Disorder disulfiram plus lorazepam - Alcohol Dependence, Anxiety Disorder | Phase 4 | Completed | University of New Mexico | 41 | 2009-08-01 | 2023-08-30 |
| Genetic and Brain Mechanisms of Naltrexone's Treatment Efficacy for Alcoholism Naltrexone 50 Mg, Placebo - Alcohol Dependence | Phase 4 | Completed | Medical University of South Carolina | 358 | 2009-06-01 | 2018-07-10 |
| Pharmacogenetic Response to Naltrexone For Alcohol Dependence naltrexone, Placebo - Alcohol Dependence | Phase 4 | Completed | David Oslin | 221 | 2009-01-05 | 2017-05-11 |
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Alcoholism (46) · Bipolar Disorder (7) · Depression (4) · Psychotic Disorders (4) · Anxiety Disorders (3) · Mania (3) · Schizophrenia (3) · Alcohol Drinking (2) · Behavior, Addictive (2) · Depressive Disorder, Major (2) · Phobia, Social (2) · Stress Disorders, Post-Traumatic (2) · Substance-Related Disorders (2) · Alcohol-Related Disorders (1) · Chemically-Induced Disorders (1)
Alcohol-Related Disorders (45) · Chemically-Induced Disorders (45) · Mental Disorders (45) · Substance-Related Disorders (44) · Behavior (9) · Mood Disorders (8) · Bipolar and Related Disorders (7) · Behavioral Symptoms (4) · Pathological Conditions, Signs and Symptoms (4) · Schizophrenia Spectrum and Other Psychotic Disorders (4) · Nervous System Diseases (3) · Neurobehavioral Manifestations (3) · Neurologic Manifestations (3) · Signs and Symptoms (3) · Compulsive Behavior (2)
Naltrexone (14) · Acamprosate (7) · vivitrol (6) · Sugars (4) · Cognitive Behavioral Therapy (3) · Ethanol (3) · Topiramate (3) · Disulfiram (2) · Dutasteride (2) · Lorazepam (2) · Practice Management, Medical (2) · Sodium Oxybate (2) · nalmefene (2) · Baclofen (1) · Control Groups (1)
Medical University of South Carolina (7) · State University of New York - Upstate Medical University (4) · UConn Health (4) · NYU Langone Health (3) · University of Texas Southwestern Medical Center (3) · H. Lundbeck A/S (2) · US Department of Veterans Affairs (2) · University of New Mexico (2) · Alkermes, Inc. (1) · Boston University (1) · CAMC Health System (1) · Catholic University of the Sacred Heart (1) · Centre for Addiction and Mental Health (1) · Chiang Mai University (1) · David Oslin (1)
United States (37) · Germany (2) · Austria (1) · Canada (1) · Finland (1) · France (1) · India (1) · Israel (1) · Italy (1) · Spain (1) · Thailand (1) · United Kingdom (1)
Steven L Batki, MD (3) · Kathleen T Brady, M.D., Ph.D. (2) · Raymond F Anton, MD (2) · Albert J. Arias, MD (1) · Alexander M Ponizovsky, MD, PhD (1) · Audis Bethea, PharmD, BCPS (1) · Bernard Le Foll, MD, PhD (1) · Bryan K Tolliver, M.D., Ph.D. (1) · Bryan K Tolliver, MD, PhD (1) · Carrie L Randall, PhD (1) · David Oslin, MD (1) · David W. Oslin, MD (1) · E. Sherwood Brown, MD PhD (1) · Edna B. Foa, PhD (1) · Edson S Brown, MD, PhD (1)
PMID 16012278, PMID 16300039, PMID 18614026, PMID 18819759, PMID 19560604, PMID 19593174, PMID 20363090, PMID 22480715, PMID 22551036, PMID 22985676, PMID 23131884, PMID 23134193, PMID 23422399, PMID 23571420, PMID 23577900, PMID 23925619, PMID 24052453, PMID 24190578, PMID 24283802, PMID 24996524, PMID 25760804, PMID 26905901, PMID 27930926, PMID 28409564, PMID 30003479, PMID 30043457, PMID 35796481, PMID 37142273, PMID 38684046, PMID 40257810, PMID 8628042
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