30 completed, 1 terminated. 31 Phase 3.
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All 31 trials
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| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|
Study of Anti-r-HuEpo Associated Pure Red Cell Aplasia (PRCA) Treatment
Cyclosporine combine with mycophenolate mofetil, Cyclophosphamide + pred - Anti-r-HuEpo Associated PRCA Subjects | Phase 3 | Terminated | 8 | 2009-01-01 | 2014-01-29 |
A Randomized Pilot Study for the Treatment of AIDS or AIDS Related Complex With an Alternating or Simultaneous Combination Regimen of AZT and 2',3'-Dideoxyinosine
zidovudine, 2',3'-dideoxyinosine - AIDS-Related Complex, Acquired Immunodeficiency Syndrome | Phase 3 | Completed | 42 | 1990-10-01 | 2008-03-04 |
A Double-Blind, Randomized, Dose Response Study of Three Doses of Delavirdine Mesylate (U-90152S) in Combination With Zidovudine (ZDV) Versus ZDV Alone in HIV-1 Infected Individuals With CD4 Counts of 200-500mm3
Delavirdine mesylate, Lamivudine, Zidovudine - HIV Infections | Phase 3 | Completed | 1250 | | 2005-06-24 |
A Treatment Protocol for the Use of Trimetrexate With Leucovorin Rescue for AIDS Patients With Pneumocystis Carinii Pneumonia and Serious Intolerance to Approved Therapies
Trimetrexate glucuronate, Leucovorin calcium - Pneumonia, Pneumocystis Carinii, HIV Infections | Phase 3 | Completed | | | 2008-09-30 |
A Phase III Randomized Trial of Topical Vaginal Fluorouracil (5-Fluorouracil, 5-FU) Maintenance Therapy Versus Observation After Standard Treatment for High-Grade Cervical Dysplasia in HIV-Infected Women
Fluorouracil - HIV Infections, Cervix, Dysplasia | Phase 3 | Completed | 158 | | 2021-11-04 |
Randomized Comparative Study of Fluconazole Versus Clotrimazole Troches in the Prevention of Serious Fungal Infection in Patients With AIDS or Advanced AIDS-Related Complex. (A Nested Study of ACTG 081)
Clotrimazole, Fluconazole - Candidiasis, Mycoses | Phase 3 | Completed | 500 | | 2021-11-02 |
A Study of Zidovudine (AZT) Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected Patients With Little or No Previous Treatment
Saquinavir, Zidovudine, Zalcitabine - HIV Infections | Phase 3 | Completed | 3000 | | 2005-06-24 |
A Comparison of Zidovudine (AZT) Used Alone or in Combination With Didanosine (ddI) or Dideoxycytidine (ddC) in HIV-Infected Patients
Zidovudine, Zalcitabine, Didanosine - HIV Infections | Phase 3 | Completed | 1200 | | 2021-11-04 |
A Study of Pentamidine Plus Dapsone in the Prevention of Pneumocystis Carinii Pneumonia (PCP) in HIV-Infected Patients Who Cannot Take Trimethoprim or Sulfonamides
Pentamidine isethionate, Dapsone - Pneumonia, Pneumocystis Carinii, HIV Infections | Phase 3 | Completed | 400 | | 2021-11-01 |
Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS
Trimetrexate glucuronate, Sulfamethoxazole-Trimethoprim, Leucovorin calcium - Pneumonia, Pneumocystis Carinii, HIV Infections | Phase 3 | Completed | 302 | | 2021-11-04 |
A Double-Blind, Randomized, Comparative Study of Delavirdine Mesylate (U-90152S) in Combination With Didanosine (ddI) Versus ddI Alone in HIV-1 Infected Individuals With CD4 Counts of <= 300/mm3
Delavirdine mesylate, Didanosine - HIV Infections | Phase 3 | Completed | | | 2005-06-24 |
Safety and Effectiveness of Giving Isotretinoin to HIV-Infected Women to Treat Cervical Tumors
Isotretinoin - HIV Infections, Cervix, Dysplasia | Phase 3 | Completed | 150 | | 2021-11-04 |
A Randomized, Comparative, Prospective Study of Daily Trimethoprim / Sulfamethoxazole (TMS) and Thrice-Weekly TMS for Prophylaxis Against PCP in HIV-Infected Patients
Sulfamethoxazole-Trimethoprim - Pneumonia, Pneumocystis Carinii, HIV Infections | Phase 3 | Completed | 2500 | | 2021-11-04 |
Treatment of Psoriasis Using Acitretin in HIV-Positive Patients
Acitretin - HIV Infections, Psoriasis | Phase 3 | Completed | 30 | | 2005-06-24 |
A Comparison of Lamivudine and Zidovudine, Used Alone and Together, in HIV-Infected Patients Who Have Not Used Zidovudine in the Past
Lamivudine, Zidovudine - HIV Infections | Phase 3 | Completed | 320 | | 2005-12-12 |
A Randomized, Open-Label Study of Alternative Treatment Combinations of Dideoxycytidine (HIVID; ddC) and Zidovudine (AZT) in Patients With HIV Infection
Zidovudine, Zalcitabine - HIV Infections | Phase 3 | Completed | 528 | | 2005-06-24 |
A Comparison of Atovaquone and Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia in HIV-Infected Patients Who Cannot Take TMP/SMX
Atovaquone, Pentamidine isethionate - Pneumonia, Pneumocystis Carinii, HIV Infections | Phase 3 | Completed | 615 | | 2005-06-24 |
The Safety and Effectiveness of Three Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Taken AZT
Lamivudine, Zidovudine, Zalcitabine - HIV Infections | Phase 3 | Completed | 325 | | 2005-06-24 |
A Phase III Study to Evaluate the Safety, Tolerance, and Efficacy of Early Treatment With Zidovudine (AZT) in Asymptomatic Infants With HIV Infection
Zidovudine - HIV Infections | Phase 3 | Completed | 400 | | 2021-10-28 |
A Phase III Randomized, Double-Blind, Controlled Study of the Use of Anti-HIV Immune Serum Globulin (HIVIG) for the Prevention of Maternal-Fetal HIV Transmission in Pregnant Women and Newborns Receiving Zidovudine (AZT)
Anti-HIV Immune Serum Globulin (Human), Globulin, Immune, Zidovudine - HIV Infections, Pregnancy | Phase 3 | Completed | 1600 | | 2008-09-30 |
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Narrower conditions
HIV Infections (29) · Acquired Immunodeficiency Syndrome (27) · Pneumonia, Pneumocystis (6) · AIDS-Related Opportunistic Infections (2) · Chickenpox (2) · Herpes Zoster (2) · Pregnancy Complications, Infectious (2) · Uterine Cervical Diseases (2) · Uterine Cervical Dysplasia (2) · Blastomycosis (1) · Candidiasis (1) · Hemophilia A (1) · Histoplasmosis (1) · Mycoses (1)
Broader conditions
Blood-Borne Infections (31) · Communicable Diseases (31) · Genital Diseases (31) · Immune System Diseases (31) · Immunologic Deficiency Syndromes (31) · Infections (31) · Lentivirus Infections (31) · RNA Virus Infections (31) · Retroviridae Infections (31) · Sexually Transmitted Diseases (31) · Sexually Transmitted Diseases, Viral (31) · Slow Virus Diseases (31) · Urogenital Diseases (31) · Virus Diseases (31) · Bacterial Infections and Mycoses (8)
Interventions
Zidovudine (15) · Didanosine (4) · Zalcitabine (4) · Lamivudine (3) · Leucovorin (3) · Pentamidine (3) · Trimethoprim, Sulfamethoxazole Drug Combination (3) · trimetrexate glucuronate (3) · Delavirdine (2) · 5-propynylarabinofuranosyluracil (1) · Acitretin (1) · Acyclovir (1) · Amphotericin B (1) · Atovaquone (1) · Clotrimazole (1)
Sponsors
National Institute of Allergy and Infectious Diseases (NIAID) (15) · Glaxo Wellcome (4) · Hoffmann-La Roche (3) · Pharmacia and Upjohn (2) · Bayer (1) · Bristol-Myers Squibb (1) · Chulalongkorn University (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · Janssen, LP (1) · National Cancer Institute (NCI) (1) · The Immune Response Corporation (1)
Countries
United States (30) · Puerto Rico (11) · Canada (2) · Tanzania (2) · Thailand (1)
Top investigators
E Connor (2) · Sattler FR (2) · Baker C (1) · Bozzettee S (1) · D Winslow (1) · DD Richman (1) · ER Stiehm (1) · El-Sadr W (1) · Englund J (1) · Feinberg J (1) · G McSherry (1) · J Lambert (1) · Kearkiat Praditpornsilpa, MD (1) · L Saravolatz (1) · Luskin-Hawk R (1)
Results publications
PMID 16220994, PMID 20103953, PMID 28154006, PMID 37461207