120 completed, 7 unknown, 3 terminated, 3 withdrawn. 50 Phase 2, 30 Phase 1, 24 Not applicable, 23 Phase 3, 8 Phase 4.
Follow Didanosine: new trials by email Literature Review of Didanosine trials Research Report on Didanosine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Clarithromycin on PK of Linaprazan, Linaprazan on PK of Clarithromycin and Linaprazan on PK of Midazolam Linaprazan glurate, Drug drug interaction (DDI) - Clarithromycin (Part I), Drug drug interaction (DDI) - Midazolam (Part 2) - Safety Issues, Pharmacokinetics | Phase 1 | Completed | Cinclus Pharma Holding AB | 35 | 2022-11-27 | 2025-01-03 |
| Evaluation of Three Strategies of Second-line Antiretroviral Treatment in Africa (Dakar - Bobo-Dioulasso - Yaoundé) emtricitabine/tenofovir + lopinavir/ritonavir (WHO recommended second line), abacavir + didanosine + lopinavir/ritonavir (WHO recommended second line), emtricitabine/tenofovir + darunavir + ritonavir (Second line strategy under evaluation) - HIV, HIV Infections | Phase 3 | Completed | ANRS, Emerging Infectious Diseases | 454 | 2009-11-01 | 2017-02-27 |
| Bioequivalence Study of Didanosine in Children Treated for HIV didanosine - HIV Infections | Phase 2 | Suspended | Assistance Publique - Hôpitaux de Paris | 26 | 2009-09-01 | 2009-02-09 |
| Effectiveness of Directly Observed Therapy in Combined HIV and Tuberculosis Treatment in Resource-limited Settings Didanosine, Efavirenz, Lamivudine - HIV Infections, Tuberculosis | Not applicable | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 592 | 2009-08-01 | 2010-03-29 |
| Optimizing Pediatric HIV-1 Treatment in Infants With Prophylactic Exposure to Nevirapine, Nairobi, Kenya AZT/3TC/NVP (zidovudine/lamivudine/nevirapine), d4T/3TC/NVP (stavudine/lamivudine/nevirapine), AZT/3TC/ABC (zidovudine/lamivudine/abacavir) - HIV Infections | Phase 3 | Terminated | University of Washington | 34 | 2007-09-01 | 2018-08-27 |
| Safety, Tolerability and Pharmacokinetics of Efavirenz in HIV-Infected Children Efavirenz (EFV) + Didanosine (ddI) + Emtricitabine (FTC) - HIV Infections | Phase 1 / Phase 2 | Completed | Bristol-Myers Squibb | 56 | 2007-02-01 | 2014-04-29 |
| Safety and Efficacy of Two Once Daily Anti Retroviral Treatment Regimens Along With Anti-tuberculosis Treatment Didanosine, Lamivudine, Efavirenz, Didanosine, Lamivudine, Nevirapine - Tuberculosis, Human Immunodeficiency Virus Infections | Phase 3 | Unknown | Tuberculosis Research Centre, India | 180 | 2006-06-01 | 2009-10-08 |
| Reducing the Incidence of Nevirapine Resistance Mutations in Pregnant HIV Infected Women Who Receive Anti-HIV Drugs Prior to and After Giving Birth Didanosine, enteric-coated, Lopinavir/ritonavir, Nevirapine - HIV Infections | Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 175 | 2006-06-01 | 2021-11-05 |
| Once-daily Highly Active Antiretroviral Treatment Regimen Administration in HIV-1 Infected Children in Burkina Faso (ANRS 12103 BURKINAME) Efavirenz (EFV), Lamivudine (3TC), Didanosine (ddI) - HIV Infections, AIDS | Phase 2 | Completed | French National Agency for Research on AIDS and Viral Hepatitis | 52 | 2006-02-01 | 2011-12-05 |
| Anti-HIV Drugs for Treating Infants Who Acquired HIV Infection at Birth Abacavir sulfate, Didanosine, Efavirenz - HIV Infections | Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 377 | 2005-07-01 | 2021-11-02 |
| Prospective Evaluation of Anti-retroviral Combinations for Treatment Naive, HIV Infected Persons in Resource-limited Settings Atazanavir, Didanosine (enteric-coated), Efavirenz - HIV Infections | Phase 4 | Completed | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | 1571 | 2005-05-01 | 2018-10-10 |
| Study to Evaluate Changes in CD4 on Replacing TDF With ABC or DDI+TDF With ABC+3TC Abacavir, Didanosine, Abacavir+Lamivudine - HIV Infections | Phase 3 | Completed | Hospital de Granollers | 75 | 2005-04-01 | 2015-03-24 |
| Strategies for Delivering Anti-HIV Therapy in South Africa Monitoring by HIV-trained primary care nurses, Community-based directly observed therapy (DOT), stavudine - HIV Infections | Not applicable | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 813 | 2005-02-01 | 2007-09-18 |
| Preventing Sexual Transmission of HIV With Anti-HIV Drugs Atazanavir, Didanosine, Efavirenz - HIV Infections | Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 3526 | 2005-02-01 | 2021-11-05 |
| One Month Dual Antiretroviral Prophylaxis to Prevent Resistance Mutations in Mothers Exposed to Single Dose Nevirapine Zidovudine (ZDV), Didanosine (ddI) - HIV Infections | Phase 2 | Completed | Institut de Recherche pour le Developpement | 244 | 2004-12-01 | 2012-01-06 |
| Once a Day (QD) - Twice a Day (BID) Clinical Trial: Didanosine, Lamivudine and Efavirenz Versus Zidovudine, Lamivudine and Efavirenz in the Starting Treatment of HIV didanosine + lamivudine + efavirenz - HIV Infections | Phase 4 | Completed | Clinical Trial Agency of HIV Study Group | 360 | 2004-06-01 | 2007-10-16 |
| A Comparison of Two Dose Levels of Didanosine Used in Combination With Stavudine in HIV-Infected Patients Stavudine, Didanosine - HIV Infections | Not applicable | Completed | Bristol-Myers Squibb | 2004-02-01 | 2011-04-25 | |
| Antiretroviral Therapy for Advanced HIV Disease in South Africa Zidovudine, Stavudine, Didanosine - HIV | Phase 4 | Completed | National Institutes of Health Clinical Center (CC) | 1771 | 2004-01-01 | 2013-05-21 |
| Feasibility Study of a Once Daily Antiretroviral Regimen in Vietnam (ANRS 1210 VIETAR) efavirenz, didanosine, lamivudine - HIV Infection | Phase 3 | Completed | French National Agency for Research on AIDS and Viral Hepatitis | 100 | 2003-09-01 | 2007-07-03 |
| A Prospective Cohort of Children With HIV Infection Zidovudine, Stavudine, Didanosine, Lamivudine, Nevirapine, Efavirenz, LPV/r, Saquinavir, Indinavir, Ritonavir, Nelfinavir - HIV Infections | Completed | The HIV Netherlands Australia Thailand Research Collaboration | 500 | 2003-03-01 | 2025-03-17 |
Showing 20 of 134. Sign in to see all of them.
HIV Infections (130) · Acquired Immunodeficiency Syndrome (45) · AIDS-Related Complex (32) · AIDS-Related Opportunistic Infections (2) · Leukoencephalopathy, Progressive Multifocal (2) · Sarcoma, Kaposi (2) · Tuberculosis (2) · AIDS Dementia Complex (1) · Brain Diseases (1) · Cardiovascular Diseases (1) · Central Nervous System Diseases (1) · Cytomegalovirus Infections (1) · Directly Observed Therapy (1) · HIV-Associated Lipodystrophy Syndrome (1) · Hemophilia A (1)
National Institute of Allergy and Infectious Diseases (NIAID) (71) · Bristol-Myers Squibb (18) · ANRS, Emerging Infectious Diseases (3) · Glaxo Wellcome (3) · AJI Pharma USA (2) · French National Agency for Research on AIDS and Viral Hepatitis (2) · Hoffmann-La Roche (2) · Merck Sharp & Dohme LLC (2) · National Cancer Institute (NCI) (2) · Pharmacia and Upjohn (2) · Triangle Pharmaceuticals (2) · Abbott (1) · Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (1) · Agouron Pharmaceuticals (1) · Argus Pharmaceuticals (1)
United States (107) · Puerto Rico (37) · Canada (7) · South Africa (6) · Thailand (6) · Brazil (3) · France (3) · India (3) · Italy (3) · Tanzania (3) · Argentina (2) · Australia (2) · Botswana (2) · Burkina Faso (2) · Kenya (2)
Richard Pollard (3) · Scott Hammer (3) · Van Dyke R (3) · Constance Benson (2) · Friedland G (2) · Genevieve Chene, MD, PhD (2) · Hammer S (2) · Hernan Valdez (2) · Hirsch M (2) · Jean-Michel Molina, MD, PhD (2) · Johnson V (2) · Katzenstein D (2) · Kimberly Smith (2) · Kline M (2)
PMID 24326304, PMID 24979445, PMID 33901188, PMID 11306155, PMID 14668455, PMID 14668456, PMID 14669723, PMID 15115831, PMID 15187476, PMID 15597521, PMID 15717256, PMID 15736019, PMID 16048984, PMID 16103764, PMID 16220085, PMID 16267764, PMID 16287792, PMID 16810109, PMID 16905783, PMID 17174704, PMID 17310819, PMID 17357053, PMID 17527093, PMID 17591032, PMID 17662759, PMID 18090046, PMID 18176329, PMID 18193496, PMID 18781872, PMID 18977721, PMID 18981766, PMID 19020325, PMID 19237646, PMID 20102271, PMID 20121419, PMID 20133267, PMID 20133268, PMID 20158398, PMID 20467286, PMID 20516271, PMID 20687947, PMID 20942650, PMID 20961784, PMID 21036772, PMID 21239359, PMID 21499794, PMID 21716078, PMID 21767103, PMID 21857286, PMID 21890776
K24AI051966 (2), 2004 (1), R01AI062512 (1), R01HD023412 (1), R01HL065953 (1), U01AI068636 (1), U19AI053217 (1)