Zalcitabine: Clinical Trials

39 trials of Zalcitabine, newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

39 completed. 16 Phase 2, 9 Not applicable, 7 Phase 3, 6 Phase 1, 1 Phase 4.

By phase and status

PhaseTrialsStatus
Phase 216Completed 16
Not applicable9Completed 9
Phase 37Completed 7
Phase 16Completed 6
Phase 41Completed 1

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Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
A Phase I Concentration-Targeted Multidose Study of Atevirdine Mesylate ( U-87201E ), AZT, and ddI or ddC
Atevirdine mesylate, Zidovudine, Zalcitabine - HIV Infections
Phase 1CompletedNational Institute of Allergy and Infectious Diseases (NIAID)302021-11-04
A Study of Dideoxycytidine Plus Zidovudine (AZT) in HIV-Infected Children Who Have Taken AZT
Zidovudine, Zalcitabine - HIV Infections
Phase 2CompletedNational Institute of Allergy and Infectious Diseases (NIAID)1802021-11-04
A Study of Zidovudine (AZT) Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected Patients With Little or No Previous Treatment
Saquinavir, Zidovudine, Zalcitabine - HIV Infections
Phase 3CompletedHoffmann-La Roche30002005-06-24
A Comparison of Zidovudine (AZT) Used Alone or in Combination With Didanosine (ddI) or Dideoxycytidine (ddC) in HIV-Infected Patients
Zidovudine, Zalcitabine, Didanosine - HIV Infections
Phase 3CompletedNational Institute of Allergy and Infectious Diseases (NIAID)12002021-11-04
A Study of Chemotherapy Plus ddI or ddC in the Treatment of AIDS-Related Kaposi's Sarcoma
Bleomycin sulfate, Vincristine sulfate, Doxorubicin hydrochloride - Sarcoma, Kaposi, HIV Infections
Phase 1CompletedNational Institute of Allergy and Infectious Diseases (NIAID)722021-10-29
The Effectiveness of Nelfinavir and Efavirenz, Used Alone or Together, Combined With Other Anti-HIV Drugs in Patients Who Have Taken Anti-HIV Drugs
Ritonavir, Nelfinavir mesylate, Efavirenz - HIV Infections
Phase 2CompletedNational Institute of Allergy and Infectious Diseases (NIAID)3002021-11-01
A Comparison of Three Treatments for Advanced HIV Disease in Patients Who Have Received Nucleoside Therapy in the Past
Zidovudine, Zalcitabine, Didanosine - HIV Infections
Phase 2CompletedNational Institute of Allergy and Infectious Diseases (NIAID)6542021-11-04
Effect of Indinavir Plus Two Other Anti-HIV Drugs on Blood Clotting in HIV-Positive Males With Hemophilia
Indinavir sulfate, Lamivudine, Stavudine - HIV Infections, Hemophilia A
Phase 4CompletedMerck Sharp & Dohme LLC552005-06-24
A Randomized, Parallel Arm, Comparative, Open Label, Multicenter Study of the Activity and Safety of Two Formulations of Saquinavir in Combination With Other Antiretroviral Drugs
Saquinavir, Lamivudine, Stavudine - HIV Infections
Phase 2CompletedHoffmann-La Roche1402005-06-24
A Study of Saquinavir and Zalcitabine, Used Alone and Together, in the Treatment of Advanced HIV Infection in Patients Who Stopped Taking or Who Cannot Take Zidovudine
Saquinavir, Zalcitabine - HIV Infections
Phase 2CompletedHoffmann-La Roche9002005-06-24
The Safety and Effectiveness of Retrovir Plus HIVID Combined With Either Nevirapine or Invirase in the Treatment of HIV Infection
Saquinavir, Nevirapine, Zidovudine - HIV Infections
Phase 2CompletedParexel2252005-06-24
Comparison of Anti HIV Drugs Used Alone or in Combination With Cytosine Arabinoside to Treat Progressive Multifocal Leukoencephalopathy (PML) in HIV-Infected Patients
Filgrastim, Cytarabine, Zidovudine - HIV Infections, Leukoencephalopathy, Progressive Multifocal
Phase 2CompletedNational Institute of Allergy and Infectious Diseases (NIAID)902021-11-01
Dideoxycytidine ( Ro 24-2027 ). A Treatment Protocol for the Use of Dideoxycytidine ( ddC ) in Patients With AIDS or Advanced ARC Who Cannot Be Maintained on Zidovudine ( AZT ) Therapy.
Zalcitabine - HIV Infections
Not applicableCompletedHoffmann-La Roche2005-06-24
A Randomized, Unblinded Trial of Zidovudine Versus ddC in the Treatment of Patients Status Post PCP Who Received Long-Term Zidovudine Therapy in Protocol ACTG 002
Zidovudine, Zalcitabine - HIV Infections
Phase 3CompletedNational Institute of Allergy and Infectious Diseases (NIAID)1202021-11-03
A Randomized, Open-Label Study of Alternative Treatment Combinations of Dideoxycytidine (HIVID; ddC) and Zidovudine (AZT) in Patients With HIV Infection
Zidovudine, Zalcitabine - HIV Infections
Phase 3CompletedHoffmann-La Roche5282005-06-24
The Antiviral Efficacy of Concurrent Zidovudine and 2',3'-Dideoxyinosine or 2',3'-Dideoxycytidine in Patients With Human Immunodeficiency Virus Disease
Zidovudine, Zalcitabine, Didanosine - HIV Infections
Not applicableCompletedGlaxo Wellcome2005-06-24
A Study on the Management of Combination Anti-HIV Drug Therapy in HIV-Positive Children With Prior Treatment
Ritonavir, Nelfinavir mesylate, Nevirapine - HIV Infections
Phase 1CompletedNational Institute of Allergy and Infectious Diseases (NIAID)2172021-10-29
The Safety and Effectiveness of Three Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Taken AZT
Lamivudine, Zidovudine, Zalcitabine - HIV Infections
Phase 3CompletedGlaxo Wellcome3252005-06-24
A Randomized, Double Blind, Comparative Study of Dideoxycytidine (ddC) Alone or ddC/AZT Combination Versus Zidovudine (ZDV) Alone in Patients With HIV Infection Who Have Received Prior ZDV Therapy
Zidovudine, Zalcitabine - HIV Infections
Phase 3CompletedNational Institute of Allergy and Infectious Diseases (NIAID)7502021-11-02
A Trial of Two Doses of 2',3'-Dideoxycytidine (ddC) in the Treatment of Children With Symptomatic HIV Infection Who Are Intolerant of AZT and/or Who Show Progressive Disease While on AZT
Zalcitabine - HIV Infections
Phase 2CompletedNational Institute of Allergy and Infectious Diseases (NIAID)1402021-10-27

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Conditions studied

HIV Infections (39)  ·  Acquired Immunodeficiency Syndrome (31)  ·  AIDS-Related Complex (25)  ·  AIDS-Related Opportunistic Infections (2)  ·  Hemophilia A (1)  ·  Hemophilia B (1)  ·  Hepatitis C (1)  ·  Leukoencephalopathy, Progressive Multifocal (1)  ·  Pneumonia, Pneumocystis (1)  ·  Sarcoma, Kaposi (1)

Sponsors

National Institute of Allergy and Infectious Diseases (NIAID) (23)  ·  Hoffmann-La Roche (10)  ·  Glaxo Wellcome (3)  ·  Immunobiology Research Institute (1)  ·  Merck Sharp & Dohme LLC (1)  ·  Parexel (1)

Countries

United States (39)  ·  Puerto Rico (12)  ·  Canada (4)  ·  Tanzania (2)  ·  Australia (1)

Top investigators

A Collier (1)  ·  Abrams D (1)  ·  Andrea Kovacs (1)  ·  Balfour HH (1)  ·  Collier AC (1)  ·  Corey L (1)  ·  Crane L (1)  ·  D Richman (1)  ·  D Winslow (1)  ·  David Katzenstein (1)  ·  Eyster ME (1)  ·  Fischl M (1)  ·  Fischl MA (1)  ·  G Skowron (1)  ·  Gill JC (1)

Results publications

PMID 18090046, PMID 22222175, PMID 37461207