The Alfred: Clinical Trials

62 completed, 22 unknown, 13 recruiting, 5 active not recruiting. 31 Not applicable, 21 Phase 2, 18 Phase 4, 10 Phase 1, 7 Phase 3.

By phase and status

Phase	Trials	Status
Not applicable	31	Completed 20, Unknown 4, Recruiting 2, Terminated 2, Active not recruiting 1, Not yet recruiting 1, Withdrawn 1
Phase 2	21	Completed 12, Recruiting 3, Unknown 2, Active not recruiting 1, Not yet recruiting 1, Terminated 1, Withdrawn 1
Phase 4	18	Completed 10, Unknown 3, Recruiting 2, Withdrawn 2, Terminated 1
Phase 1	10	Completed 3, Recruiting 3, Unknown 3, Terminated 1
Phase 3	7	Completed 3, Active not recruiting 1, Recruiting 1, Terminated 1, Unknown 1

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Remote Monitoring for Patients With Aortic Stenosis Aortic Stenosis		Not yet recruiting	Baker Heart and Diabetes Institute	160	2026-09-01	2026-07-08
Inhibiting the Anti-apoptotic Factor, BCL-2, at the Time of ART Initiation to Promote Apoptosis of HIV-infected Cells and Restrict the Seeding of the HIV Reservoir (The INITIATE Study) Venetoclax - HIV-1	Phase 1	Recruiting	Thomas Aagaard Rasmussen	38	2026-04-13	2026-05-07
PeRiOperative Medicine Platform Trial Liberal inspired oxygen, Conservative inspired oxygen, Intermediate inspired oxygen - Surgical Site Infection After Major Surgery, Anaesthesia	Phase 4	Recruiting	Monash University	7800	2026-04-06	2026-04-17
Dilation Optimisation for Uniform Bioprosthetic Leaflet Expansion 'Double tap' balloon post-dilation - Aortic Stenosis, TAVI(Transcatheter Aortic Valve Implantation)	Not applicable	Not yet recruiting	The Alfred	250	2026-04-01	2026-02-24
The AminoECMO Pilot Trial Synthamin-17 (10% amino acid solution), Placebo (Hartmann's balanced crystalloid solution) - Acute Kidney Injury	Phase 2	Not yet recruiting	Australian and New Zealand Intensive Care Research Centre	40	2026-02-01	2026-02-27
Ventilation Imaging to Improve the Quality of Life for Patients With Lung Cancer Treated With Radiation Therapy Healthy lung sparing treatment plan - Lung Cancer	Phase 3	Recruiting	University of Sydney	165	2026-01-01	2026-05-19
Treponemal Shedding, Load, and Viability, in Women and Men-who-have-sex-with-women-only With Early Infectious Syphilis: Implications for Transmission No Intervention: Observational Cohort - Syphilis		Recruiting	Monash University	480	2025-12-02	2026-04-03
Creating A Risk Assessment Tool for Thunderstorm Asthma: the CARISTA Study Observational - Allergic Asthma, Thunderstorm Asthma	Not applicable	Recruiting	University of Melbourne	530	2025-08-27	2026-05-06
Young Stroke Service Deep Phenotyping: Exploring Recovery in Young Adult Survivors of Stroke Observational Cohort - Stroke Patients, Stroke		Recruiting	The Florey Institute of Neuroscience and Mental Health	100	2025-07-19	2026-04-21
Study Investigating the Role of Routine Screening and Molecular Characterisation of Brain Metastasis in the Management of High-risk Metastatic Breast Cancer computerized tomography - Breast Cancer Metastatic, Brain Metastasases		Not yet recruiting	Monash University	45	2024-12-01	2024-12-11
Administration of Venetoclax to Promote Apoptosis of HIV-infected Cells and Reduce the Size of the HIV Reservoir Among People Living With HIV on ART Venetoclax - HIV-1-infection	Phase 1 / Phase 2	Recruiting	University of Aarhus	18	2024-04-01	2026-09-17
PrognostICate- Study:Prognostication of ICU- and Ventilator- Days Over the Next Years Until 2040 Intensive Care Unit (ICU) treatment - ICU Admission		Unknown	University Hospital of Cologne	10000000	2024-03-01	2024-07-23
Secondary Access - FEmoral or Radial in Transcatheter Aortic Valve Implantation? Access site - Valve Stenoses, Aortic	Not applicable	Completed	The Alfred	542	2024-02-02	2026-08-12
Risk-guided Disease managEment Plan to prevEnt CAD in Patients Treated With Previous Cancer Coronary CT - Coronary Artery Disease		Recruiting	Baker Heart and Diabetes Institute	748	2023-10-18	2025-12-04
D-Cycloserine Augmentation of Intermittent Theta Burst Stimulation (iTBS) in Depression (COGENT) D-Cycloserine, Intermittent Theta Burst Stimulation - Major Depressive Disorder	Phase 2	Active not recruiting	The Alfred	180	2023-04-21	2025-12-04
Low Dose Nivolumab in Adults Living With HIV on Antiretroviral Therapy Nivolumab 10 MG/ML [Opdivo], Saline - HIV I Infection	Phase 1 / Phase 2	Recruiting	University of Melbourne	42	2023-01-24	2025-12-22
Human Papillomavirus in Young People Epidemiological Research 4 Human Papillomavirus Infection, HPV		Unknown	Monash University	500	2023-01-01	2023-03-15
Human Papillomavirus in Young People Epidemiological Research 3 Human Papillomavirus Infection, HPV		Unknown	Monash University	200	2023-01-01	2023-03-15
Trial of Venovenous ECMO to De-Sedate, Extubate and Mobilise in Hypoxic Respiratory Failure Venovenous ECMO - Mechanical Ventilation Complication, Hypoxemia	Not applicable	Recruiting	Australian and New Zealand Intensive Care Research Centre	140	2022-11-28	2024-08-09
The SHIELD Study-silicosis Silicosis		Unknown	The University of Queensland	120	2022-08-16	2022-09-21

Showing 20 of 116. Sign in to see all of them.

Conditions studied

Heart Failure (12)  ·  HIV Infections (9)  ·  Psychotic Disorders (9)  ·  Schizophrenia (9)  ·  Mental Disorders (8)  ·  Critical Illness (7)  ·  Depression (7)  ·  Depressive Disorder, Major (7)  ·  Cystic Fibrosis (5)  ·  Motor Activity (5)  ·  COVID-19 (4)  ·  Neoplasms (4)  ·  Pulmonary Disease, Chronic Obstructive (4)  ·  Aortic Valve Stenosis (3)  ·  Heart Arrest (3)

Interventions

Raloxifene Hydrochloride (4)  ·  Lactose (3)  ·  Transcranial Magnetic Stimulation (3)  ·  tibolone (3)  ·  Escitalopram (2)  ·  Estradiol (2)  ·  Exercise (2)  ·  Milrinone (2)  ·  Nitrous Oxide (2)  ·  Sodium Chloride (2)  ·  venetoclax (2)  ·  Acetylcysteine (1)  ·  Antidepressive Agents (1)  ·  Ascorbic Acid (1)  ·  Aspirin (1)

Countries

Australia (106)  ·  Canada (3)  ·  Denmark (3)  ·  Germany (3)  ·  New Zealand (3)  ·  India (2)  ·  United Kingdom (2)  ·  United States (2)  ·  Belgium (1)  ·  Brazil (1)  ·  China (1)  ·  France (1)  ·  Hong Kong (1)  ·  Ireland (1)  ·  Malaysia (1)

Top investigators

Henry Krum, MBBS FRACP PhD (4)  ·  Anne E Holland, PhD (3)  ·  David Barton (3)  ·  Gavin Lambert (3)  ·  Jayashri Kulkarni, MBBS, MPM, FRANZCP, PhD (3)  ·  Paul B Fitzgerald, MBBS, PhD (3)  ·  Sharon Lewin, Professor (3)  ·  Abdul Khalid (2)  ·  Aidan Burrell, MBBS (2)  ·  Benjamin J Tarrant, B.Physio (2)  ·  Jayashri Kulkarni, PhD,FRANZP (2)  ·  Jennifer Hoy, A/Prof (2)  ·  Mark C Fitzgerald, MBBS, MD (2)  ·  Sharon Lewin (2)  ·  Adam Kucharski, MMath, PhD (1)

Results publications

PMID 31239657, PMID 31415936, PMID 33511633, PMID 34043963, PMID 34971362, PMID 10659482, PMID 15930979, PMID 15947013, PMID 16246187, PMID 17904915, PMID 17911499, PMID 18245143, PMID 18796097, PMID 19145228, PMID 19174807, PMID 19293069, PMID 19454032, PMID 19933409, PMID 22349069, PMID 23219310, PMID 23872668, PMID 24011178, PMID 25435055, PMID 25725625, PMID 26945746, PMID 27438995, PMID 27456448, PMID 27549782, PMID 27604363, PMID 27672116, PMID 28611235, PMID 28716784, PMID 29046921, PMID 29549516, PMID 29643011, PMID 29723767, PMID 30316548, PMID 30688793, PMID 31142242, PMID 31418515, PMID 31950979, PMID 32179935, PMID 32291773, PMID 32370765, PMID 32389109, PMID 32565447, PMID 32705292, PMID 32985249, PMID 33010149, PMID 33228654

NIH funding

2025 (2)