4 completed, 2 active not recruiting, 2 unknown, 1 not yet recruiting. 6 Not applicable, 1 Phase 1, 1 Phase 2, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 3, Unknown 2, Active not recruiting 1 |
| Phase 1 | 1 | Active not recruiting 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Terminated 1 |
| Phase 4 | 1 | Withdrawn 1 |
Follow Radionuclide Generators: new trials by email Literature Review of Radionuclide Generators trials Research Report on Radionuclide Generators
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| SMART Study in Real World SyMapCath I™ catheter and SYMPIONEER S1™ Stimulator/Generator - Hypertension, Uncontrolled Hypertension | Not yet recruiting | SyMap Medical (Suzhou), Ltd. | 1000 | 2025-02-01 | 2025-02-17 | |
| Endovascular Denervation for the Treatment of Type 2 Diabetes Mellitus Endovascular denervation System (Generator and Catheter ) - Type 2 Diabetes Mellitus (T2DM) | Not applicable | Unknown | Shanghai Golden Leaf MedTec Co. Ltd | 30 | 2022-12-27 | 2024-04-09 |
| A Study of Multi-electrode Circular Irreversible Electroporation (IRE) Catheter and Multi-Channel IRE Generator in Paroxysmal Atrial Fibrillation (AF) Multi-Channel Irreversible Electroporation (IRE) Generator, Multi-Channel Circular IRE Catheter - Refractory Paroxysmal Atrial Fibrillation | Not applicable | Completed | Biosense Webster, Inc. | 142 | 2022-12-07 | 2026-01-06 |
| Sympathetic Mapping/ Ablation of Renal Nerves Trial - Hemodialysis SyMapCath I™ catheter and SYMPIONEER S1™ Stimulator/Generator - Hypertension, Hemodialysis | Not applicable | Unknown | The Second Hospital of Nanjing Medical University | 30 | 2021-05-01 | 2021-05-04 |
| To Evaluate Safety and Efficacy of a Radiofrequency Renal Denervation System in Treatment of Essential Hypertension Renal Artery Radiofrequency Ablation System (Generator and Catheter ), Antihypertensive Agents, Sham Procedure - Hypertension | Not applicable | Completed | Shanghai Golden Leaf MedTec Co. Ltd | 205 | 2021-01-19 | 2023-01-04 |
| VSV-hIFNbeta-NIS With or Without Ruxolitinib Phosphate in Treating Stage IV or Recurrent Endometrial Cancer Biopsy, Computed Tomography, Fluorine F 18 Tetrafluoroborate - Metastatic Endometrial Carcinoma, Recurrent Endometrial Adenocarcinoma | Phase 1 | Active not recruiting | Mayo Clinic | 34 | 2017-09-15 | 2026-07-21 |
| Sympathetic Mapping/ Ablation of Renal Nerves Trial SyMapCath I™ catheter and SYMPIONEER S1™ Stimulator/Generator - Hypertension | Not applicable | Active not recruiting | SyMap Medical (Suzhou), Ltd. | 220 | 2016-06-30 | 2023-08-02 |
| REVOLUTION (WFCC-133) - Treatment of Paroxysmal Atrial Fibrillation nMARQ™ System - Paroxysmal Atrial Fibrillation | Phase 2 | Completed | Biosense Webster, Inc. | 186 | 2011-03-01 | 2017-06-06 |
| Study Comparing Radio Frequency Ablation Plus Chemotherapy and Chemotherapy Alone in Patients With Secondary Liver Metastases Radiofrequency Ablation (RFA), Chemotherapy - Metastatic Liver Cancer, Secondary Liver Cancer | Phase 4 | Withdrawn | Boston Scientific Corporation | 2007-08-01 | 2017-03-03 | |
| Harmonic™ vs. Electrocautery in Abdominoplasties Ultrasonic scalpel, monopolar electrosurgery generator and tip - Skin and Fat Redundancy and Muscle Diastases | Not applicable | Completed | Ethicon Endo-Surgery | 70 | 2006-10-01 | 2015-08-04 |
| Guidant Microwave Ablation System for the Treatment of Atrial Fibrillation Flex 4 and Generator - Atrial Fibrillation | Phase 3 | Terminated | Boston Scientific Corporation | 200 | 2005-06-01 | 2016-01-06 |
Hypertension (4) · Atrial Fibrillation (3) · Colorectal Neoplasms (1) · Diabetes Mellitus, Type 2 (1) · Diastasis, Muscle (1) · Endometrial Neoplasms (1) · Liver Neoplasms (1)
Biosense Webster, Inc. (2) · Boston Scientific Corporation (2) · Shanghai Golden Leaf MedTec Co. Ltd (2) · SyMap Medical (Suzhou), Ltd. (2) · Ethicon Endo-Surgery (1) · Mayo Clinic (1) · The Second Hospital of Nanjing Medical University (1)
China (6) · United States (4) · Germany (2) · Argentina (1) · Belgium (1) · Czechia (1) · Denmark (1) · France (1) · Italy (1) · Mexico (1)
Drik F Richter, M.D. (1) · Gao-Jun Teng, MD (1) · Hailong Tao (1) · Heng Cai (1) · Hua Fu (1) · Jamie N. Bakkum-Gamez, M.D. (1) · JianPing LI, MD (1) · Jianzeng Dong (1) · Lianjun Gao (1) · Michael Mack, MD (1) · Prof. Pierre Jais, MD (1) · Shaowen Liu (1) · William Jacqmein (1) · Yujie Zhou, MD (1)
PMID 34269698, PMID 36042146, PMID 38756107, PMID 41233363, PMID 42205100
R01CA207240 (1)