53 completed, 21 unknown, 15 recruiting, 9 terminated. 50 Not applicable, 36 Phase 2, 26 Phase 1, 10 Phase 3, 1 Early Phase 1.
Follow Electroporation: new trials by email Literature Review of Electroporation trials Research Report on Electroporation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Irreversible Electroporation (IRE) for the Treatment of Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH) Irreversible Electroporation - Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH) | Not applicable | Not yet recruiting | Angiodynamics, Inc. | 40 | 2026-09-01 | 2026-06-11 |
| ¹⁸F-PSMA-1007 PET-CT-Directed Focal Therapy for MRI-Invisible Prostate Cancer Focal Therapy for Prostate Cancer - Prostate Cancer | Not applicable | Recruiting | The University of Hong Kong | 60 | 2026-08-20 | 2026-08-26 |
| International Study on Treatment of Liver (HCC) Patients With IRE Irreversible Electroporation - Hepatocellular Carcinoma (HCC), Liver Ablation | Not applicable | Not yet recruiting | Angiodynamics, Inc. | 50 | 2026-02-01 | 2025-10-10 |
| International Study on Treatment of Patients With Metastatic Colorectal Liver Lesions Patients With IRE Irreversible Electroporation - Colorectal Adenocarcinoma Metastatic in the Liver, Liver Ablation | Not applicable | Not yet recruiting | Angiodynamics, Inc. | 50 | 2026-02-01 | 2025-10-10 |
| CUIMC Focal Therapy Registry Focal therapy - Prostate Cancer | Recruiting | Columbia University | 1000 | 2026-01-01 | 2026-06-03 | |
| Irreversible Electroporation for Recurrent or Metastatic Cervical Lymph Node Metastases From Thyroid Cancer: A Prospective Multicenter Single-Arm Study Irreversible Electroporation (IRE) Ablation - Thyroid Cancer Patients, Lymph Node Metastasis | Not applicable | Recruiting | Tian'an Jiang | 85 | 2025-12-17 | 2026-07-23 |
| IRE Combined With the Dual-Function Antibody PD-1/CTLA-4 for the Treatment of LAPC Following Failure of First-Line AG Therapy Irreversible electroporation, Dual-Function Antibody PD-1/CTLA-4 - Pancreatic Adenocarcinoma Locally Advanced | Phase 2 | Recruiting | Ruijin Hospital | 20 | 2025-12-15 | 2025-12-29 |
| Registry for Prostate Cancer Focal Therapy Focal Therapy for Prostate Cancer - Prostate Cancer | Recruiting | The University of Hong Kong | 200 | 2025-10-31 | 2026-08-28 | |
| Irreversible Electroporation (NanoKnife ®) and Immunotherapy for the Treatment of Stage IV Colorectal Cancer IRE plus checkpoint inhibitor, IRE plus Checkpoint Inhibitor plus CpG-ODN - Liver Metastasis Colon Cancer | Phase 1 / Phase 2 | Not yet recruiting | University of Saskatchewan | 12 | 2025-07-01 | 2024-08-09 |
| Systemic Therapy With a Loco-regional Treatment in Patients With Locally Advanced Pancreatic Cancer Irreversible electroporation (NanoKnife® ) - Locally Advanced Pancreatic Cancer, Irreversible Electroporation | Not applicable | Recruiting | University of Saskatchewan | 27 | 2025-05-01 | 2025-05-13 |
| Irreversible Electroporation (IRE) for Treating Recurrent Pelvic Tumors (PELFIRE Study) Irreversible electroporation - Colorectal Carcinoma, Renal Cancer | Recruiting | Amsterdam UMC, location VUmc | 27 | 2025-04-18 | 2026-08-28 | |
| Irreversible Electroporation Combined With Targeted Therapy and Immunotherapy for Advanced Hepatocellular Carcinoma Irreversible Electroporation, Lenvatinib, Sintilimab - Hepatocellular Carcinoma (HCC) | Phase 2 | Recruiting | Shunda Du | 30 | 2025-04-01 | 2026-09-21 |
| Irreversible Electroporation Ablation Combined With Anti-PD(L)1 Therapy for Locally Advanced Pancreatic Cancer Irreversible electroporation - Pancreatic Cancer | Not yet recruiting | Ruijin Hospital | 55 | 2024-11-10 | 2024-11-07 | |
| Comparison of Different Electroporation Systems in the Ablation Treatment of Atrial Fibrillation Electroporation - AF, Ablation of Atrial Fibrillation | Not applicable | Active not recruiting | University Hospital Dubrava | 150 | 2024-10-15 | 2025-04-01 |
| COLDFIRE-III Trial: Efficacy of Irreversible Electroporation and Stereotactic Body Radiotherapy for Perivascular and Peribiliary Colorectal Liver Metastases Irreversible electroporation, Stereotactic body radiotherapy - Colorectal Cancer, Liver Metastases | Phase 2 / Phase 3 | Recruiting | Amsterdam UMC, location VUmc | 78 | 2024-08-20 | 2024-08-23 |
| Intra-tumoral Mitazalimab (CD40 Antibody) With Irreversible Electroporation (IRE) in Locally Advanced Pancreas Cancer IRE + intratumoral mitazalimab (CD40 antibody) injection, NanoKnife - Pancreatic Cancer | Phase 1 | Recruiting | University of California, San Diego | 18 | 2024-07-17 | 2026-06-25 |
| A Pan-Canadian, Investigator Initiated Clinical Trial With Focal IRE Directed to Intermediate-Risk Prostate Cancer Irreversible Electroporation (NanoKnife) - Prostate Cancer | Not applicable | Recruiting | University Health Network, Toronto | 100 | 2024-05-16 | 2026-06-11 |
| Irreversible Electroporation & Pembro Immunotherapy in Locally Advanced Pancreatic Cancer Pembrolizumab, Irreversible Electroporation - Pancreatic Cancer, Locally Advanced Pancreatic Cancer | Phase 1 | Completed | H. Lee Moffitt Cancer Center and Research Institute | 2 | 2024-04-10 | 2026-02-09 |
| Pulsed Field Ablation During Left Atrial Appendage Occlusion: A Randomised Controlled Trial Catheter ablation of atrial fibrillation using Pulsed Field Ablation, Left atrial appendage occlusion - Atrial Fibrillation | Not applicable | Withdrawn | Liverpool Heart and Chest Hospital NHS Foundation Trust | 2024-04-01 | 2024-07-19 | |
| Prospective Asian Multicenter Prostate Cancer Focal Therapy Study (ProAMFocal) Focal Therapy for Prostate Cancer - Prostate Cancer | Recruiting | Singapore General Hospital | 500 | 2023-05-06 | 2024-07-08 |
Showing 20 of 114. Sign in to see all of them.
Pancreatic Neoplasms (18) · Prostatic Neoplasms (14) · Carcinoma, Hepatocellular (9) · Liver Neoplasms (7) · Colorectal Neoplasms (4) · Lung Neoplasms (4) · Head and Neck Neoplasms (3) · Kidney Neoplasms (3) · Melanoma (3) · Neoplasm Metastasis (3) · Atrial Fibrillation (2) · Carcinoma, Renal Cell (2) · Cholangiocarcinoma (2) · HIV Infections (2) · Liver Diseases (2)
Fuda Cancer Hospital, Guangzhou (30) · Amsterdam UMC, location VUmc (5) · Angiodynamics, Inc. (4) · National Taiwan University Hospital (4) · Insel Gruppe AG, University Hospital Bern (3) · Ole Thorlacius-Ussing, MD, DMSc, Professor of Surgery (3) · The University of Texas Health Science Center, Houston (3) · University of Saskatchewan (3) · Clinical Research Office of the Endourological Society (2) · Copenhagen University Hospital, Rigshospitalet (2) · Dr. M.R. Meijerink (2) · H. Lee Moffitt Cancer Center and Research Institute (2) · Ismail Gögenur (2) · Karolinska Institutet (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2)
China (37) · United States (18) · Denmark (11) · Netherlands (10) · United Kingdom (5) · Canada (4) · France (3) · Italy (3) · Slovenia (3) · Switzerland (3) · Taiwan (3) · Germany (2) · Hong Kong (2) · Puerto Rico (2) · Sweden (2)
Lizhi Niu, PhD (14) · Lizhi Niu, PHD (4) · Martijn R Meijerink, MD, PhD (4) · Jibing Chen, PhD (3) · Kai-Wen Huang, PhD (3) · Mathias Worni, MD (3) · Ajith Siriwardena, MD FRCS (2) · Ole Thorlacius-Ussing, Professor, DMSc (2) · Robert Martin, MD, PhD (2) · Ahmad Tarhini, MD, PhD (1) · Alessandro Vitale, MD (1) · Anil K Pillai, MD (1) · Anna Lantz, Ass Prof (1) · Arian R van Erkel, MD, PhD (1)
PMID 24861662, PMID 25354827, PMID 25765775, PMID 25886058, PMID 25902855, PMID 26118600, PMID 26296371, PMID 26365543, PMID 26497813, PMID 26774149, PMID 26777402, PMID 27150293, PMID 28003034, PMID 28209559, PMID 28654336, PMID 28912804, PMID 28931520, PMID 30235286, PMID 31410175, PMID 31687922, PMID 32493267, PMID 32681477, PMID 33093457, PMID 33724066, PMID 34754076, PMID 36723911, PMID 36895163, PMID 38513683, PMID 39054460, PMID 39088271, PMID 39417680, PMID 40139834, PMID 40803526, PMID 42205100
2016 (2), 2009 (1), R01CA282439 (1), UM1CA121947 (1)