Oxygen: Clinical Trials

27 trials of Oxygen, newest first

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27 completed. 27 Phase 2, 4 Phase 3, 3 Phase 1.

By phase and status

PhaseTrialsStatus
Phase 227Completed 27
Phase 34Completed 4
Phase 13Completed 3

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Trials (filtered) newest first · largest first

All 27 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Oxygen as an Acute Treatment in Alternating Hemiplegia of Childhood
Oxygen, Placebo - Alternating Hemiplegia of Childhood
Phase 2CompletedAssistance Publique - Hôpitaux de Paris242024-09-162026-04-13
Oxygen Targets in Acute Heart Failure With Pulmonary Congestion
Oxygen - Acute Heart Failure, Pulmonary Congestion
Phase 2 / Phase 3CompletedCopenhagen University Hospital, Hvidovre1352024-02-012026-10-26
Blend to Limit Oxygen in ECMO: A Randomised Controlled Registry Trial
Oxygen - Cardiac Failure, Critical Illness
Phase 2CompletedAustralian and New Zealand Intensive Care Research Centre3002019-09-182024-08-09
The Effect of Oxygen Therapy on 6MWD in PAH and CTEPH Patients With Hypoxemia
Oxygen - Oxygen Deficiency, Pulmonary Arterial Hypertension
Phase 2CompletedHeidelberg University202019-04-012024-06-20
Maternal Hyperoxygenation in Congenital Heart Disease
Maternal Hyperoxygenation - Hypoplastic Left Heart Syndrome
Phase 1 / Phase 2CompletedThe Hospital for Sick Children252018-02-022024-03-26
Combined Upper-airway and Breathing Control Therapies for Obstructive Sleep Apnea
Oral appliance, Oxygen, Oral appliance plus oxygen - Obstructive Sleep Apnea
Phase 2CompletedBrigham and Women's Hospital412017-09-062025-05-04
Use of Oxygen in Heart Failure With Preserved Ejection Fraction
oxygen - Heart Failure
Phase 2CompletedHull University Teaching Hospitals NHS Trust502016-11-032019-06-26
EMONO for the Treatment of Peripheral Neuropathic Pain
Medical Air, EMONO - Neuralgia
Phase 2CompletedAir Liquide Santé International2872016-11-012018-09-21
Risk of Oxygen During Cardiac Surgery Trial
Oxygen - normoxia, Oxygen - hyperoxia - Cardiac Surgery
Phase 2 / Phase 3CompletedVanderbilt University2132016-04-052024-02-01
Aerosol Deposition in Asthmatic Obese Women Using Heliox
nebulizing with heliox and oxygen - Obese, Asthma
Phase 2CompletedJacqueline de Melo Barcelar202015-11-012016-09-15
rEduction of oXygen After Cardiac arresT: a Pilot Study
Oxygen - Heart Arrest
Phase 2CompletedMonash University592015-07-012017-09-07
Reduction of Venous Emboli Load After Breathing Normobaric Oxygen Compared to Air
Oxygen, Air - Hyperbaric, Diving Medicine
Phase 2 / Phase 3CompletedGöteborg University482015-05-012022-05-27
Nitric Oxide to Treat Pulmonary Embolism
Inhaled Nitric Oxide, Sham - Pulmonary Embolism
Phase 2CompletedIndiana University782013-10-012018-10-03
Three-level Injection Paravertebral Block vs General Anesthesia in Mastectomy
paravertebral block, fentanyl, propofol, atracurium, lidocaine , adrenaline, ketamine bolus, midazolam - Radical Mastectomy
Phase 1 / Phase 2CompletedRamathibodi Hospital602013-10-012014-03-10
Hyperbaric Treatment of Traumatic Brain Injury (TBI)
Oxygen at 1.5 ATA (atmospheres absolute). - Traumatic Brain Injury
Phase 1 / Phase 2CompletedBarry Miskin, MD182013-04-012021-04-27
Analgesic Effect of IV Acetaminophen in Tonsillectomies
Acetaminophen (paracetamol), Normal Saline Flush, Midazolam - Adenotonsillitis, Tonsillitis
Phase 2CompletedNationwide Children's Hospital2502012-10-012017-04-06
Normobaric Oxygen (NBO) Therapy in Acute Migraine
Oxygen, Room air - Migraine
Phase 2CompletedMassachusetts General Hospital222012-07-012017-03-27
Effect of Ambulatory Oxygen on the Walking Test in Patients With Pulmonary Fibrosis
oxygen, medical air - Pulmonary Fibrosis
Phase 2CompletedUniversity of Siena322012-04-012016-01-29
Study of Inhaled Carbon Monoxide to Treat Idiopathic Pulmonary Fibrosis
inhaled carbon monoxide, Oxygen - Idiopathic Pulmonary Fibrosis
Phase 2CompletedBrigham and Women's Hospital582011-07-012017-06-14
RATNO, Reducing Antibiotic Tolerance Using Nitric Oxide in CF - a Phase 2 Pilot Study
Nitric Oxide, Control - Cystic Fibrosis
Phase 2CompletedUniversity Hospital Southampton NHS Foundation Trust122011-05-012024-05-30

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Conditions studied

Heart Failure (2)  ·  Hyperoxia (2)  ·  Hypoxia (2)  ·  Pulmonary Fibrosis (2)  ·  Sleep Apnea, Obstructive (2)  ·  Acne Vulgaris (1)  ·  Alternating hemiplegia of childhood (1)  ·  Arrhythmias, Cardiac (1)  ·  Asthma (1)  ·  Brain Injuries, Traumatic (1)  ·  Critical Illness (1)  ·  Cystic Fibrosis (1)  ·  Decompression Sickness (1)  ·  Delirium (1)  ·  Dermatitis, Atopic (1)

Sponsors

Brigham and Women's Hospital (2)  ·  Air Liquide Santé International (1)  ·  Aria Aesthetics Inc. (1)  ·  Assistance Publique - Hôpitaux de Paris (1)  ·  Australian and New Zealand Intensive Care Research Centre (1)  ·  Barry Miskin, MD (1)  ·  Copenhagen University Hospital, Hvidovre (1)  ·  Göteborg University (1)  ·  Heidelberg University (1)  ·  Hull University Teaching Hospitals NHS Trust (1)  ·  Indiana University (1)  ·  Jacqueline de Melo Barcelar (1)  ·  London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1)  ·  Massachusetts General Hospital (1)  ·  Monash University (1)

Countries

United States (11)  ·  Australia (3)  ·  Canada (3)  ·  Brazil (2)  ·  France (2)  ·  Germany (2)  ·  Denmark (1)  ·  Saint Kitts and Nevis (1)  ·  Sweden (1)  ·  Thailand (1)  ·  United Kingdom (1)

Top investigators

Andrew Clark (1)  ·  Aneesh B Singhal, MD (1)  ·  Arlyne Thung, MD (1)  ·  Barry Miskin, MD (1)  ·  Benno von Bormann, MD (1)  ·  Bradley A Edwards, PhD (1)  ·  David Pilcher (1)  ·  Didier Bouhassira, MD (1)  ·  Frederic T. Billings, IV, MD, MSc (1)  ·  Gary Connett, FRCPCH MD (1)  ·  Harriet Hopf, M.D. (1)  ·  Ida Taraldsen, MD (1)  ·  James Zacny, Ph.D. (1)  ·  Jeff A Kline, MD (1)  ·  Jens Hove, MD, PhD (1)

Results publications

PMID 19151054, PMID 26056838, PMID 26296299, PMID 27206964, PMID 28329240, PMID 28454823, PMID 28651648, PMID 29100885, PMID 29610659, PMID 29684433, PMID 30633959, PMID 33044394, PMID 34914658, PMID 35050957, PMID 37876374, PMID 38629477, PMID 39110454, PMID 39162827, PMID 39688178, PMID 39705180, PMID 40069946, PMID 40673571

NIH funding

1UM1HL113203-01A1 (1), R01DA008391 (1), R01GM112871 (1), R01HL128658 (1), U01HL105371 (1)