6 completed, 1 recruiting, 1 unknown. 3 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 3 |
| Phase 1 | 1 | Completed 1 |
Follow Alternating hemiplegia of childhood: new trials by email Literature Review of Alternating hemiplegia of childhood trials Research Report on Alternating hemiplegia of childhood
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oxygen as an Acute Treatment in Alternating Hemiplegia of Childhood Oxygen, Placebo - Alternating Hemiplegia of Childhood | Phase 2 | Completed | Assistance Publique - Hôpitaux de Paris | 24 | 2024-09-16 | 2026-04-13 |
| Validation of a Clinical Assessment Scale Specific to Alternating Hemiplegia interview with neurologist - Alternating Hemiplegia | Completed | Hospices Civils de Lyon | 17 | 2023-11-18 | 2025-02-27 | |
| HEmiplegia Arrhythmia Retrospective Trial Recording of clinical parameters and electrocardiogram parameters - Alternating Hemiplegia of Childhood | Completed | Hospices Civils de Lyon | 20 | 2021-04-29 | 2023-02-22 | |
| Observe Alternating Hemiplegia of Childhood (OBSERV-AHC) Study Review of past medical history, clinical exam, and electroencephalogram, polysomnography and urine samples of melatonin and pupillometry., The patients' parents have to complete the VINELAND II adaptive behavior scales scoring, The Sleep Disturbance Scale for Children (SDSC) and Horne & Ostberg Circadian Typology Questionnaire - Alternating Hemiplegia | Completed | Hospices Civils de Lyon | 34 | 2019-10-28 | 2023-01-12 | |
| Natural History Study of ATP1A3-related Disease Whole exome sequencing - ATP1A3-related Disease, Alternating Hemiplegia of Childhood | Unknown | Institute of Child Health | 100 | 2018-09-01 | 2022-06-06 | |
| Pilot Study, Comparative, Single-center, Randomized, Crossover, Double-blind, Against Placebo, Testing the Effectiveness of Triheptanoin Oil in Alternating Hemiplegia of Childhood Triheptanoin, Placebo - Alternating Hemiplegia of Childhood | Phase 2 | Completed | Institut National de la Santé Et de la Recherche Médicale, France | 10 | 2015-03-25 | 2025-12-10 |
| Sodium Oxybate in Patients With Alternating Hemiplegia of Childhood (AHC-SO) Sodium Oxybate - Alternating Hemiplegia of Childhood | Phase 1 / Phase 2 | Completed | University of Utah | 6 | 2009-08-01 | 2014-03-31 |
| Studies of the Variable Phenotypic Presentations of Rapid-Onset Dystonia Parkinsonism and Other Movement Disorders Dystonia, Parkinsonism | Recruiting | State University of New York at Buffalo | 198 | 2008-04-01 | 2026-10-28 |
Dystonia 12 (2) · Arrhythmias, Cardiac (1) · CAPOS syndrome (1) · Dystonia (1) · Parkinsonian Disorders (1)
Pathological Conditions, Signs and Symptoms (2) · Basal Ganglia Diseases (1) · Brain Diseases (1) · Cardiovascular Diseases (1) · Central Nervous System Diseases (1) · Dyskinesias (1) · Heart Diseases (1) · Movement Disorders (1) · Nervous System Diseases (1) · Neurologic Manifestations (1) · Pathologic Processes (1) · Signs and Symptoms (1)
Exome Sequencing (1) · Interviews as Topic (1) · Neurologists (1) · Oxygen (1) · Sodium Oxybate (1) · triheptanoin (1)
Hospices Civils de Lyon (3) · Assistance Publique - Hôpitaux de Paris (1) · Institut National de la Santé Et de la Recherche Médicale, France (1) · Institute of Child Health (1) · State University of New York at Buffalo (1) · University of Utah (1)
France (5) · United States (2) · United Kingdom (1)
Allison Brashear, MD (1) · Emmanuel Flamand-Roze, MD, PhD (1) · Helen Cross, PhD (1) · Kathryn J. Swoboda, M.D. (1)
PMID 22924536, PMID 24436111, PMID 28969699
R01NS058949 (1)