3 recruiting, 2 terminated, 2 unknown, 1 completed. 8 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Recruiting 3, Terminated 2, Unknown 2, Completed 1 |
| Phase 3 | 2 | Terminated 1, Unknown 1 |
Follow Ventricular Dysfunction, Right: new trials by email Literature Review of Ventricular Dysfunction, Right trials Research Report on Ventricular Dysfunction, Right
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Inhaled Milrinone and Epoprostenol for the Prevention of Difficult Cardiac Pulmonary Bypass Separation Combined Epoprostenol Sodium & Milrinone, Normal saline - Right Heart Failure, Right Ventricular Dysfunction | Phase 2 | Recruiting | Montreal Heart Institute | 141 | 2025-12-10 | 2026-06-25 |
| Feasibility Trial for a Right Ventricular Failure Platform Trial Empagliflozin, Ranolazine - Pulmonary Hypertension, Right Ventricular Dysfunction | Phase 2 | Recruiting | University of Alberta | 30 | 2025-07-15 | 2026-10-15 |
| Effects of Inhaled Nitric Oxide on Sublingual Microcirculation in Patients With Right Ventricular Dysfunction After Cardiac Surgery Inhaled Nitric Oxide (iNO) use - Cardiac Surgery Intensive Care Treatment, Pulmonary Hypertension | Phase 2 | Completed | Southeast University, China | 60 | 2024-10-01 | 2026-11-05 |
| Repurposing Valsartan May Protect Against Pulmonary Hypertension Valsartan 40 mg, Placebo - Pulmonary Arterial Hypertension, Right Heart Failure | Phase 2 | Recruiting | University of Washington | 60 | 2024-02-28 | 2026-05-04 |
| Using TEE to Evaluate the Effect of Levosimendan on Patients With ARDS Associated With RVD During MV levosimendan, 5% glucose injection - Transesophageal Echocardiography, Acute Respiratory Distress Syndrome | Phase 2 / Phase 3 | Unknown | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 58 | 2023-03-22 | 2023-03-14 |
| Right Ventricular Dysfunction in Tetralogy of Fallot: Inhibition of the Renin-angiotensin-aldosterone System Losartan, Placebo - Tetralogy of Fallot, Heart Defects, Congenital | Phase 2 | Unknown | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 120 | 2013-12-01 | 2015-12-22 |
| Diclofenac for Submassive PE Diclofenac, Placebo - Pulmonary Embolism | Phase 2 / Phase 3 | Terminated | Ministry of Health, Spain | 34 | 2012-05-01 | 2017-09-06 |
| Tenecteplase Pulmonary Embolism Italian Study tenecteplase - Pulmonary Embolism | Phase 2 | Terminated | University Of Perugia | 180 | 2004-07-01 | 2008-05-06 |
Heart Failure (3) · Hypertension, Pulmonary (2) · Pulmonary Embolism (2) · Heart Defects, Congenital (1) · Inflammation (1) · Pulmonary Arterial Hypertension (1) · Respiratory Distress Syndrome (1) · Tetralogy of Fallot (1)
Cardiovascular Diseases (8) · Heart Diseases (8) · Ventricular Dysfunction (8) · Lung Diseases (6) · Respiratory Tract Diseases (6) · Vascular Diseases (4) · Embolism (2) · Embolism and Thrombosis (2) · Hypertension (2) · Cardiovascular Abnormalities (1) · Congenital Abnormalities (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Hypertension, Pulmonary (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1)
Diclofenac (1) · Glucose (1) · Inosine (1) · Losartan (1) · Milrinone (1) · Ranolazine (1) · Saline Solution (1) · Simendan (1) · Tenecteplase (1) · Valsartan (1) · empagliflozin (1)
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Ministry of Health, Spain (1) · Montreal Heart Institute (1) · Southeast University, China (1) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (1) · University Of Perugia (1) · University of Alberta (1) · University of Washington (1)
Canada (2) · China (2) · Italy (1) · Netherlands (1) · Spain (1) · United States (1)
Cecilia Becattini, MD (1) · David Jimenez, MD, PhD (1) · Giancarlo Agnelli, MD (1) · Jason Weatherald, MD,MSc,FRCPC (1) · Peter Leary, MD, PhD (1)
PMID 11082382, PMID 11606352, PMID 12456409, PMID 14639158, PMID 15999045, PMID 16236968, PMID 16547439, PMID 17400468, PMID 17566702, PMID 18378625, PMID 19559822, PMID 19794327, PMID 19833379, PMID 22578975, PMID 27378592, PMID 28526144, PMID 28598920, PMID 29222139, PMID 29247809, PMID 31585674, PMID 32682511, PMID 7574953, PMID 8103681, PMID 9201062, PMID 9288373
R61HL167848 (1)