48 completed, 13 unknown, 8 terminated, 7 recruiting. 87 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 87 | Completed 48, Unknown 13, Terminated 8, Recruiting 7, Withdrawn 5, Active not recruiting 3, Not yet recruiting 2, Enrolling by invitation 1 |
Follow Venous Insufficiency: new trials by email Literature Review of Venous Insufficiency trials Research Report on Venous Insufficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Open Label Safety Investigation of Solutio™ Tumescent Catheter Administration of local anesthesia - Venous Insufficiency | Not applicable | Not yet recruiting | MedVasc AB | 30 | 2026-09-28 | 2026-09-16 |
| PROfunda Femoris Vein Thrombosis Evaluation and Clearance to Improve Outcomes of Endovascular Treatment for Acute Iliofemoral Deep Vein Thrombosis Endovascular treatment with profunda femoris vein thrombosis clearance (Endovascular treatment with PFV-TC), Percutaneous mechanical thrombectomy without profunda femoris vein thrombosis clearance (PMT without PFV-TC) - Deep Vein Thrombosis | Not applicable | Recruiting | RenJi Hospital | 140 | 2026-06-24 | 2026-10-13 |
| Acute or Subacute Iliofemoral Vein Thrombosis: Aspiration for Flow Restoration Versus Standard Anticoagulation Thrombosis aspiration - Deep Vein Thrombosis of Lower Limb, Postthrombotic Syndrome | Not applicable | Not yet recruiting | Weiwei Wu | 104 | 2026-05-01 | 2026-05-07 |
| Relatıonshıp Between Pelvıc Floor and Venous Insuffıcıency Pelvic exercise group, control group - Chronic Venous Insufficiency, Pelvic Floor, Exercise | Not applicable | Enrolling by invitation | Istanbul Arel University | 32 | 2026-03-05 | 2026-04-01 |
| RECANA OUS - Recana Thrombectomy Catheter System for Venous Obstruction and Occlusion Study (RECANA-OUS-UK) Recana Thrombectomy Catheter System - Venous Obstruction | Not applicable | Recruiting | Intervene, Inc. | 30 | 2025-10-18 | 2026-05-06 |
| Comparison of the Effects of Kinesio Taping and Interval Exercise in Patients Diagnosed With Venous Insufficiency: A Randomised Controlled Trial Kinesio Taping and Lifestyle Advice, Kinesio Taping and Interval Exercise with Lifestyle Advice, Lifestyle Advice for Venous Insufficiency - Chronic Venous Insufficiency C2 and Below | Not applicable | Active not recruiting | Necmettin Erbakan University | 49 | 2025-09-22 | 2026-10-28 |
| RECANA OUS - Recana Thrombectomy Catheter System for Venous Obstruction and Occlusion Study (RECANA-OUS-IRL) Recana procedure - Venous Obstruction | Not applicable | Recruiting | Intervene, Inc. | 20 | 2025-07-02 | 2026-05-27 |
| Outcomes of Iliac Vein Stenting With Dedicated Venous Stents in Treatment of Chronic Post-thrombotic Venous Ulcers dedicated venous stenting, Dedicated venous stent / iliofemoral dedicated venous stenting - Vascular, DVT - Deep Vein Thrombosis | Not applicable | Recruiting | Ain Shams University | 20 | 2025-03-02 | 2026-08-13 |
| Non-healing Venous Leg Ulcers Treated With Standard Care With or Without BR-AC BR-AC, Standard Care - Non-infected Venous Leg Ulcer, Venous Leg Ulcer | Not applicable | Completed | BioStem Technologies | 71 | 2025-02-14 | 2026-11-04 |
| DVT Burden and the Risk of Post-thrombotic Syndrome Quantification of deep vein thrombosis burden and assessment of post-thrombotic syndrome - Postthrombotic Syndrome | Not applicable | Recruiting | Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer | 400 | 2024-06-05 | 2026-07-07 |
| Effects of Reformer Pilates in Pregnant Women Reformer pilates exercises - Pregnancy Related, Pelvic Floor Disorders | Not applicable | Recruiting | Izmir Democracy University | 30 | 2024-02-06 | 2025-01-16 |
| The ROle of Compression StocKings in Heart Failure Patients low grade compression stockings (10-15 mmHg), high grade compression stockings (20-30 mmHg) - Heart Failure，Congestive, Leg Edema | Not applicable | Unknown | University of Maryland, Baltimore | 50 | 2024-01-17 | 2024-10-02 |
| PICO Venous Leg Ulcers (VLU) Reimbursement Study PICO Treatment, Standard of Care (SOC) Treatment - Venous Insufficiency, Venous Leg Ulcer | Not applicable | Terminated | Smith & Nephew, Inc. | 142 | 2023-12-29 | 2026-01-08 |
| Long-term Effects of Inspiratory Muscle Training in Chronic Venous Insufficiency Training group: Inspiratory muscle training, Control group: Thoracic expansion exercise - Chronic Venous Insufficiency | Not applicable | Terminated | Izmir Democracy University | 40 | 2023-09-15 | 2025-05-18 |
| Structured Exercise Versus Endovascular Reconstruction in Post Thrombotic Syndrome exercise, Deep venous stenting - Post Thrombotic Syndrome | Not applicable | Unknown | Guy's and St Thomas' NHS Foundation Trust | 54 | 2023-09-05 | 2023-09-13 |
| Exercise Tolerance After Venous Recanalization for Post-thrombotic Syndrome Stress test - Post Thrombotic Syndrome, Venous Thromboses | Not applicable | Completed | University Hospital, Montpellier | 22 | 2023-04-17 | 2025-05-30 |
| DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombosis ClotTriever System, Commercially available/market approved anticoagulation medication including but not limited to: Heparin Sodium, Coumadin, Rivaroxaban, Apixaban, etc. - Venous Thromboembolism, Deep Venous Thrombosis | Not applicable | Recruiting | Inari Medical | 300 | 2023-01-06 | 2026-11-03 |
| Comparison of Zero- and Two-centimeter Distance From Sapheno-femoral Junction in Laser Ablation of Varicose Vein Saphenous Ablation, Endogenous Laser Ablation (EVLA), mixture of 20 mL 2% lidocaine, 1: 200,000 adrenaline and 20 mL 0.5% levobupivacaine in 1 L of 0.9% saline - Varicose Veins, Venous Reflux | Not applicable | Unknown | Mansoura University | 800 | 2023-01-04 | 2023-01-31 |
| Efficacy of Complex Decongestive Therapy (CDT) in Patients With Venous Insufficiency: a Experimental Study Complex Decongestive Therapy (CDT) in venous insufficiency, - Lymphatic Edema, Cellulitis of Leg | Not applicable | Completed | University of Salamanca | 21 | 2022-10-01 | 2025-10-07 |
| A Clinical Study to Evaluate the Effectiveness of a Novel Portable Non-Pneumatic Active Compression Device vs. an Advanced Pneumatic Compression Device for Treating Lower Extremity Lymphedema Cross over Device (PCD or Dayspring - alternate to first group) - Lymphedema, Lymphedema of Leg | Not applicable | Completed | Koya Medical, Inc. | 121 | 2022-09-06 | 2025-12-12 |
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Postthrombotic Syndrome (28) · Venous Thrombosis (21) · Varicose Ulcer (16) · Varicose Veins (16) · Motor Activity (5) · Edema (4) · Lymphedema (3) · Thrombosis (3) · Gastroesophageal Reflux (2) · Leg Ulcer (2) · Pain (2) · Postphlebitic Syndrome (2) · Ulcer (2) · Venous Thromboembolism (2)
Cardiovascular Diseases (87) · Vascular Diseases (86) · Embolism and Thrombosis (29) · Thrombosis (26) · Skin Diseases (18) · Skin Ulcer (18) · Skin and Connective Tissue Diseases (18) · Leg Ulcer (16) · Varicose Veins (13) · Pathological Conditions, Signs and Symptoms (12) · Signs and Symptoms (8) · Venous Thrombosis (8) · Behavior (6) · Pathologic Processes (6)
Exercise (6) · Radiofrequency Ablation (3) · Manual Lymphatic Drainage (2) · Standard of Care (2) · Anesthesia, General (1) · Catheter Ablation (1) · Conservative Treatment (1) · Conversion to Open Surgery (1) · Drug Therapy (1) · Educational Status (1) · Elasticity Imaging Techniques (1) · Epinephrine (1) · Exercise Test (1) · Exercise Therapy (1) · Fitness Trackers (1)
Imperial College London (5) · Helsinki University Central Hospital (2) · Hull University Teaching Hospitals NHS Trust (2) · Intervene, Inc. (2) · Istanbul University - Cerrahpasa (2) · Izmir Democracy University (2) · Maastricht University Medical Center (2) · Mahidol University (2) · University Hospital, Montpellier (2) · Ain Shams University (1) · Angiodynamics, Inc. (1) · Arizona Cardiovascular Consultants (1) · Assiut University (1) · Association Francaise pour la Recherche Thermale (1) · Binghamton University (1)
United States (25) · France (11) · United Kingdom (9) · Turkey (Türkiye) (7) · Brazil (3) · Finland (3) · Germany (3) · Sweden (3) · Canada (2) · Egypt (2) · Italy (2) · Netherlands (2) · Switzerland (2) · Austria (1) · Belgium (1)
Ian C Chetter, MBChB (2) · Maarit Venermo, MD,PhD (2) · Stephen Black, MD (2) · Abdul H Sultan (1) · Alun Davies (1) · Alun Davies, MA DM FRCS FHEA (1) · Alun Davies, PhD (1) · Alun H Davies (1) · Antonia Perez Martin, MD PhD (1) · Arie Bass, Prof. (1) · Ayesha Zia, M.D (1)
PMID 39968829, PMID 20510634, PMID 33464575, PMID 15810046, PMID 15866245, PMID 16835515, PMID 19017588, PMID 19422443, PMID 19958985, PMID 20347543, PMID 20559172, PMID 20578224, PMID 21256773, PMID 21283981, PMID 21325669, PMID 21337794, PMID 21618499, PMID 21638277, PMID 22172244, PMID 22545895, PMID 23034121, PMID 23160149, PMID 23176966, PMID 23452204, PMID 23988361, PMID 24082798, PMID 24424141, PMID 24558028, PMID 24666170, PMID 24722790, PMID 25593121, PMID 26025146, PMID 26853645, PMID 26992578, PMID 27707417, PMID 27919609, PMID 27982166, PMID 28440041, PMID 28624002, PMID 29150995, PMID 29277134, PMID 29652086, PMID 29856509, PMID 30132797, PMID 30149775, PMID 30237155, PMID 30314712, PMID 31735108, PMID 31959059, PMID 31992538
K23HL132054 (1), R01HL137913 (1), R21AG080424 (1), R21NR010604 (1)