297 completed, 38 unknown, 19 terminated, 17 recruiting. 406 Phase 3, 71 Phase 2.
Follow Vector Borne Diseases: new trials by email Literature Review of Vector Borne Diseases trials Research Report on Vector Borne Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| OPTIMAL LEAP: Optimizing Dihydroartemisinin-Piperaquine IPTsc Intervals to Advance Learning, Executive Function, Attendance, and Antimalarial Resistance Surveillance in Kenyan Schoolchildren Monthly DP, Quarterly DP - Malaria, Asymptomatic Malaria | Phase 3 | Not yet recruiting | Indiana University | 1500 | 2028-01-01 | 2026-09-01 |
| Trial to Evaluate the Immunogenicity and Safety of the Co-administration of Live Attenuated Dengue and Chikungunya Vaccines Compared to Separate Administration in Adults Aged 18 to 59 Years. DENGUE: Dengue 1,2,3,4 (attenuated) vaccine CHIKUNGUNYA: Chikungunya (CHIKV) live attenuated vaccine (VLA1555), DENGUE: Dengue 1,2,3,4 (attenuated) vaccine, Chikungunya (CHIKV) live attenuated vaccine (VLA1555) - Dengue, Chikungunya | Phase 3 | Not yet recruiting | Butantan Institute | 900 | 2027-03-31 | 2026-07-16 |
| Study Comparing Several Drugs to Understand Which Work Against Cutaneous Leishmaniasis (CL) Sodium Stibogluconate (SSG), Miltefosine, Miltefosine + Paromomycin - Cutaneous Leihmaniasis | Phase 3 | Not yet recruiting | Institute of Tropical Medicine, Belgium | 900 | 2027-01-01 | 2026-03-10 |
| Different Treatment Frequencies for Hepatic Fibrosis Due to Schistosomiasis Praziquantel 40 mg/kg per dose given once annually, Praziquantel 40 mg/kg given three times per year - Schistosomiasis, Schistosoma Mansoni | Phase 2 / Phase 3 | Not yet recruiting | Rhode Island Hospital | 600 | 2026-11-01 | 2026-08-12 |
| Therapeutics for Moderate and Severe Dengue Placebo, Dexamethasone, N-Acetylcysteine - Dengue, Severe Dengue | Phase 3 | Not yet recruiting | Oxford University Clinical Research Unit, Vietnam | 8800 | 2026-10-01 | 2026-04-21 |
| Better Options for Lymphatic Filariasis Treatment MoxDA - Moxidectin + Diethylcarbamzine (DEC) + Albendazole, IDA - Ivermectin + DEC + albendazole - Lymphatic Filariasis, Scabies | Phase 3 | Recruiting | Medicines Development for Global Health | 5100 | 2026-09-28 | 2026-10-07 |
| Emetine for Viral Outbreaks (a.k.a. EVOLVE Antiviral Initiative) Emetine Hydrochloride 6mg, Placebo, Emetine Hydrochloride 12mg - Dengue | Phase 2 / Phase 3 | Recruiting | Johns Hopkins University | 600 | 2026-09-01 | 2026-10-13 |
| An Ultra-short Course of Primaquine for the Radical Cure of Vivax Malaria High dose ultra short Primaquine, Placebo - Malaria | Phase 3 | Not yet recruiting | Menzies School of Health Research | 1019 | 2026-06-01 | 2026-03-12 |
| An Efficacy, Safety, and Immunogenicity Study of CHIKV VLP Vaccine for the Prevention of Chikungunya Disease in Adolescents and Adults CHIKV VLP vaccine, Placebo - Chikungunya Virus | Phase 3 | Recruiting | Bavarian Nordic | 6144 | 2026-05-26 | 2026-11-13 |
| A Seamless Phase II/III, Observer-blind, to Evaluate Immunogenicity and Safety of Chikungunya Virus Vaccine in Healthy Subjects 12-65Years of Age. BBV87 Chikungunya vaccine, Placebo - Active Immunisation for Chikungunya Virus Infection | Phase 2 / Phase 3 | Recruiting | Bharat Biotech International Limited | 1000 | 2026-04-20 | 2026-04-29 |
| A Study of CP-COV03 Compared With Placebo in Participants With Dengue (Part 1) and Dengue-like Illness (Part 2) CP-COV03, Placebo - Dengue | Phase 2 / Phase 3 | Recruiting | Hyundai Bioscience Co., Ltd. | 210 | 2026-04-09 | 2026-07-10 |
| A Study to Learn About the Safety, Tolerability, and Immunogenicity of a Fifth Dose of 6-Valent OspA-Based Lyme Disease Vaccine VLA15, Placebo - Lyme Disease | Phase 3 | Recruiting | Pfizer | 1712 | 2026-04-08 | 2026-05-06 |
| Postpartum 8-aminoquinoline Breast Milk Study Daily primaquine (0.5 mg/kg per day) for 14 days given with food food and water, Daily primaquine 1 mg/kg per day for 7 days given with food and water, Single-dose tafenoquine given with food and water to prevent gastrointestinal discomfort - Drug Pharmacokinetics in Healthy Volunteers | Phase 2 / Phase 3 | Not yet recruiting | Curtin University | 60 | 2026-04-01 | 2026-03-18 |
| Arnica Tincture Fot the Treatment of Cutaneous Leishmaniasis II. Arnica Tincture, Meglumine antimoniate. - Leishmaniasis, Cutaneous | Phase 3 | Recruiting | Universidad de Antioquia | 96 | 2026-03-11 | 2026-04-02 |
| Butantan-DV Vaccine in Elderly Populations (DEN-04-IB) Dengue 1,2,3,4 (attenuated) vaccine - Dengue | Phase 3 | Active not recruiting | Butantan Institute | 997 | 2026-03-03 | 2026-11-10 |
| A Trial to Evaluate the Safety and Immunogenicity of VLA1553 in Healthy Children VLA1553, Control - Chikungunya Virus Infection | Phase 3 | Withdrawn | Valneva Austria GmbH | 2026-02-06 | 2025-12-31 | |
| A Study of Dengue Tetravalent Vaccine (TDV) in Adults (Age 45 to 60 and >60 to 79 Years) TDV, Placebo - Dengue Fever | Phase 3 | Active not recruiting | Takeda | 800 | 2026-01-20 | 2026-09-22 |
| A Study to Learn About Different Dosing Schedules of a Lyme Disease Vaccine in Healthy Adults VLA15, Placebo - Lyme Borreliosis | Phase 3 | Active not recruiting | Pfizer | 207 | 2025-11-19 | 2026-05-06 |
| A Study on a New Tetravalent Dengue Vaccine (TDV) Formulation in Healthy Adults Tetravalent Dengue Vaccine (TDV) - Dengue Fever | Phase 3 | Active not recruiting | Takeda | 496 | 2025-11-07 | 2026-07-17 |
| Phase 3 Single Arm, Open Study on vYF in Adults Yellow fever vaccine (live) - Yellow Fever | Phase 3 | Completed | Sanofi Pasteur, a Sanofi Company | 254 | 2025-10-23 | 2026-02-03 |
Showing 20 of 406. Sign in to see all of them.
Malaria (169) · Malaria, Falciparum (60) · Dengue (33) · Encephalitis, Japanese (32) · Leishmaniasis, Cutaneous (24) · Malaria, Vivax (22) · Chikungunya Fever (15) · Anemia (13) · Chagas Disease (13) · Leishmaniasis, Visceral (13) · Severe Dengue (13) · Encephalitis, Tick-Borne (10) · Lyme Disease (10) · Schistosomiasis (10) · Yellow Fever (10)
Infections (401) · Mosquito-Borne Diseases (297) · Parasitic Diseases (289) · Protozoan Infections (269) · Virus Diseases (108) · RNA Virus Infections (106) · Arbovirus Infections (96) · Flaviviridae Infections (83) · Flavivirus Infections (81) · Euglenozoa Infections (65) · Central Nervous System Diseases (51) · Central Nervous System Infections (51) · Nervous System Diseases (50) · Neuroinflammatory Diseases (44)
fanasil, pyrimethamine drug combination (39) · Artemether, Lumefantrine Drug Combination (36) · Chloroquine (29) · Primaquine (21) · Amodiaquine (19) · Artesunate (19) · Azithromycin (15) · miltefosine (14) · Meglumine Antimoniate (12) · Praziquantel (12) · Doxycycline (11) · Paromomycin (11) · amodiaquine, artesunate drug combination (11) · pyronaridine tetraphosphate, artesunate drug combination (11) · Ivermectin (10)
London School of Hygiene and Tropical Medicine (52) · Pfizer (17) · Sanofi Pasteur, a Sanofi Company (17) · Valneva Austria GmbH (16) · University of Oxford (15) · Drugs for Neglected Diseases (14) · GlaxoSmithKline (11) · Institute of Tropical Medicine, Belgium (11) · University of California, San Francisco (11) · Takeda (10) · Menzies School of Health Research (8) · Liverpool School of Tropical Medicine (7) · Sanofi (7) · Medicines for Malaria Venture (6) · National Institute of Allergy and Infectious Diseases (NIAID) (6)
Uganda (34) · Kenya (33) · Burkina Faso (32) · United States (31) · Brazil (29) · Tanzania (22) · Thailand (21) · Mali (20) · Colombia (18) · Ghana (18) · Democratic Republic of the Congo (17) · The Gambia (15) · India (13) · Philippines (13) · Ethiopia (12)
Grant Dorsey, MD, PhD (6) · Diane V Havlir, MD (4) · Astrid Kaltenboeck, Ph.D. (3) · Brian Greenwood, FRCP, FRS (3) · Brian Greenwood, MD (3) · Eric Ottesen, MD (3) · Jayaram Menon, MBBS (3) · Nigel Hill, PhD (3) · Paul J Milligan, PhD (3)
PMID 39324693, PMID 40099800, PMID 23433102, PMID 26666916, PMID 11873261, PMID 22610930, PMID 32228663, PMID 39116904, PMID 10656038, PMID 20934459, PMID 21849081, PMID 22993389, PMID 25425434, PMID 26214039, PMID 27007959, PMID 27418050, PMID 27459266, PMID 28379954, PMID 28871961, PMID 29300876, PMID 29324864, PMID 29547881, PMID 29897841, PMID 33020153, PMID 33212068, PMID 33822015, PMID 34003796, PMID 34219653, PMID 35659904, PMID 35709798, PMID 35732155, PMID 36534705, PMID 37321235, PMID 38294972, PMID 8937280, PMID 9790423, PMID 11500748, PMID 12510893, PMID 16235350, PMID 16503464, PMID 16551365, PMID 16640611, PMID 16702588, PMID 16837678, PMID 17046467, PMID 17239256, PMID 17519409, PMID 17519410, PMID 17582067, PMID 17940319
2019 (3), 2023 (3), 2008 (2), 2014 (2), P01HD059454 (2), 2009 (1), 2015 (1), 2016 (1), 2018 (1), 2025 (1), P60AR036308 (1), R01AI031561 (1), R01AI104702 (1), R01AI184979 (1), U01AI126610 (1)