4 completed, 2 unknown, 1 recruiting, 1 suspended. 9 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 9 | Completed 4, Unknown 2, Recruiting 1, Suspended 1, Withdrawn 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow Unipolar Depression: new trials by email Literature Review of Unipolar Depression trials Research Report on Unipolar Depression
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Title: Safety and Feasibility of Individualized Low Amplitude Seizure Therapy (iLAST) MRI, MagPro TMS stimulator and coil, Thymatron (R) System IV paired with 4X1 HDECT - Unipolar Depression | Phase 1 | Withdrawn | National Institute of Mental Health (NIMH) | 2025-02-26 | 2025-02-27 | |
| Enoxolone in Major Depression - Biomarker-outcome Relationship Enoxolone - Unipolar Depression | Phase 1 / Phase 2 | Recruiting | Philipps University Marburg | 80 | 2022-09-23 | 2025-12-08 |
| Home-administered tDCS for Treatment of Depression Soterix Medical mini-CT tDCS stimulator - Unipolar Depression, Treatment Resistant Depression | Phase 1 | Completed | Soterix Medical | 50 | 2021-02-10 | 2023-01-30 |
| Ketamine as an Adjunctive Therapy for Major Depression Ketamine, Midazolam - Major Depressive Episode, Unipolar Depression | Phase 1 | Completed | St Patrick's Hospital, Ireland | 25 | 2017-09-07 | 2020-01-18 |
| Ketamine Trial for the Treatment of Depression Ketamine, Placebo - Unipolar Depression | Phase 1 | Completed | The University of New South Wales | 10 | 2015-03-01 | 2023-03-30 |
| Effects of Repeated Attachment Security Priming on Depressed Mood: a Clinical Study Attachment security priming - Unipolar Depression | Phase 1 | Unknown | University of Southampton | 100 | 2012-11-01 | 2012-09-26 |
| Depression Outcomes Study of Exercise Public Health Dose of Exercise (PHD), Low Dose Exercise (LD) - Unipolar Depression | Phase 1 | Completed | National Institute of Mental Health (NIMH) | 9 | 2012-09-01 | 2013-03-14 |
| Open Study Assessing the Feasibility of Minocycline in Patients With Unipolar Depression Minocycline - Unipolar Depression | Phase 1 | Unknown | Shalvata Mental Health Center | 30 | 2012-06-01 | 2012-07-04 |
| Low Field Magnetic Stimulation (LFMS) in Mood Disorders: 6 Treatments Low Field Magnetic Stimulation Device - Bipolar Depression, Unipolar Depression | Phase 1 | Suspended | Mclean Hospital | 200 | 2010-05-01 | 2016-04-13 |
Depressive Disorder (9) · Bipolar Disorder (2) · Depression (2) · Consciousness Disorders (1) · Depressive Disorder, Major (1) · Depressive Disorder, Treatment-Resistant (1) · Motor Activity (1)
Mental Disorders (9) · Mood Disorders (9) · Behavior (2) · Behavioral Symptoms (2) · Bipolar and Related Disorders (2) · Nervous System Diseases (1) · Neurobehavioral Manifestations (1) · Neurocognitive Disorders (1) · Neurologic Manifestations (1) · Pathological Conditions, Signs and Symptoms (1) · Signs and Symptoms (1)
Ketamine (2) · Exercise (1) · Glycyrrhetinic Acid (1) · Midazolam (1) · Minocycline (1)
National Institute of Mental Health (NIMH) (2) · Mclean Hospital (1) · Philipps University Marburg (1) · Shalvata Mental Health Center (1) · Soterix Medical (1) · St Patrick's Hospital, Ireland (1) · The University of New South Wales (1) · University of Southampton (1)
United States (3) · Australia (1) · Germany (1) · Ireland (1) · Israel (1) · United Kingdom (1)
Abhishek Datta, PhD (1) · Andrea L Dunn, PhD (1) · Colleen K Loo, MBBS, MD (1) · Declan M McLoughlin, PhD (1) · Harald Murck, MD PhD (1) · Michael L. Rohan, Ph.D. (1) · Sarah H Lisanby, M.D. (1) · Yechiel Levkovitz, MD, PhD (1)
PMID 14702256, PMID 15780843, PMID 35036831, PMID 39428602
2016 (1)