3 recruiting, 2 completed. 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Recruiting 3, Completed 2 |
Follow Tuberculous Meningitis: new trials by email Literature Review of Tuberculous Meningitis trials Research Report on Tuberculous Meningitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| BPaLMZ for TB Meningitis BPaLMZ Regimen - Tuberculous Meningitis, HIV | Phase 2 | Recruiting | David Boulware | 312 | 2026-07-28 | 2026-10-16 |
| Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide Versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents With Tuberculous Meningitis Rifampicin (RIF), Isoniazid (INH), Linezolid (LZD) - Tuberculous Meningitis | Phase 2 | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 330 | 2023-12-07 | 2026-06-02 |
| Tnf Inhibitors to Reduce Mortality in HIV-1 Infected PAtients With Tuberculosis meNIngitis Adalimumab Injection - Tuberculous Meningitis, HIV I Infection | Phase 2 | Recruiting | ANRS, Emerging Infectious Diseases | 130 | 2023-04-11 | 2025-12-15 |
| A Pilot Study of Adjunctive Aspirin for the Treatment of HIV Negative Adults With Tuberculous Meningitis 81mg aspirin, 1000mg aspirin, Placebo - Tuberculous Meningitis | Phase 2 | Completed | Oxford University Clinical Research Unit, Vietnam | 120 | 2014-10-17 | 2017-03-07 |
| Rifampicin Explorative PK Study for Tuberculous Meningitis Comparing Oral and Intravenous Preparation Rifampicin intravenous, Oral rifampicin - Tuberculous Meningitis | Phase 2 | Completed | Universitas Padjadjaran | 30 | 2013-06-01 | 2014-06-17 |
Tuberculosis, Meningeal (5) · Central Nervous System Diseases (1) · Latent Tuberculosis (1) · Meningitis (1) · Tuberculosis (1)
Actinomycetales Infections (5) · Bacterial Infections (5) · Bacterial Infections and Mycoses (5) · Central Nervous System Bacterial Infections (5) · Central Nervous System Infections (5) · Gram-Positive Bacterial Infections (5) · Infections (5) · Meningitis, Bacterial (5) · Mycobacterium Infections (5) · Nervous System Diseases (5) · Neuroinflammatory Diseases (5) · Tuberculosis, Central Nervous System (5) · Tuberculosis, Extrapulmonary (5) · Central Nervous System Diseases (4) · Meningitis (4)
Rifampin (2) · Adalimumab (1) · Aspirin (1) · Ethambutol (1) · Isoniazid (1) · Linezolid (1) · Pyrazinamide (1)
ANRS, Emerging Infectious Diseases (1) · David Boulware (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Oxford University Clinical Research Unit, Vietnam (1) · Universitas Padjadjaran (1)
Brazil (2) · Vietnam (2) · India (1) · Indonesia (1) · Kenya (1) · Malawi (1) · Mexico (1) · Mozambique (1) · Peru (1) · Philippines (1) · South Africa (1) · Tanzania (1) · Thailand (1) · Uganda (1) · Zambia (1)
David Boulware, MD (1) · Guy Thwaites, MD, PhD (1) · Nguyen H Phu, MD, PhD (1) · Rovina Ruslami, M.D., PhD (1)