31 completed, 12 unknown, 7 withdrawn, 6 recruiting. 17 Not applicable, 5 Phase 2, 4 Phase 3, 3 Phase 1, 2 Early Phase 1.
Follow Transfusion Reaction: new trials by email Literature Review of Transfusion Reaction trials Research Report on Transfusion Reaction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Challenge Transfusion of INTERCEPT Pathogen Reduced Red Blood Cells (RBCs) in Subjects With or Without Pre-existing Antibodies to INTERCEPT RBCs 30-40 mL of INTERCEPT RBCs, ~30 mL of INTERCEPT RBCs plus plus 10 mL biotinylated INTERCEPT RBCs - Transfusion Reaction, Hemolytic | Phase 2 | Not yet recruiting | Cerus Corporation | 25 | 2026-10-10 | 2026-10-14 |
| Antihistamine for Prevention of HTR After Blood Primed CPB Antihestamine, Placebo - Blood Transfusion Associated Adverse Reactions | Phase 4 | Recruiting | Kasr El Aini Hospital | 40 | 2026-03-01 | 2026-04-21 |
| Comparison of the Proteome in ICU Patients in Search for TRALI Biomarkers: A Case-control Study Using Both Retrospective and Prospective Samples Blood sample collection - Transfusion-Related Acute Lung Injury, ARDS, Human | Not yet recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 210 | 2025-12-01 | 2025-09-04 | |
| Hip Fracture Surgery Timing and Blood Transfusion Risk in Patients on DOACs Blood Transfusion, Hip Fracture Surgeries | Recruiting | St. Antonius Hospital | 374 | 2025-11-01 | 2025-12-30 | |
| Clinical Performance Study of Safety Test ABO Device Safety Test ABO and ABTest Card® - Transfusion Reaction | Not applicable | Unknown | Diagast | 100 | 2024-09-01 | 2024-08-09 |
| Clinical Performance Study of the ABTest Card® Device. ABTest Card®REF and ABTest Card®NEW - Transfusion Reaction | Not applicable | Unknown | Diagast | 200 | 2024-09-01 | 2024-08-16 |
| Respiratory Trends During Blood Transfusions in Newborns. lung ultrasound - Blood Transfusion Complication, Blood Transfusion Associated Adverse Reactions | Not applicable | Unknown | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 71 | 2024-07-01 | 2024-09-24 |
| Re-infusion of Unwashed Shed Blood During Off-pump Surgery Re-infusion of unwashed shed blood - Coronary Artery Disease, Blood Transfusion Complication | Not applicable | Completed | Damascus University | 50 | 2024-03-27 | 2026-09-01 |
| The Safety and Efficacy of Autologous Transfusion in Spinal Surgery for Lung Cancer With Spinal Metastasis Autoblood transfusion - Spinal Metastases, Blood Transfusion Complication | Not applicable | Recruiting | Guangdong Provincial People's Hospital | 118 | 2024-03-15 | 2024-07-12 |
| Investigation of the Relationship Between Blood Transfusion Volume and Development of Renal Failure in Pediatric Patients Undergoing Cardiovascular Surgery blood transfusion - Congenital Cardiac Defect, Acute Renal Injury | Completed | Hacettepe University | 205 | 2024-01-31 | 2025-03-21 | |
| INTERCEPT Safety Evaluation on Whole Blood Amustaline/GSH pathogen reduction technology, Standard of Care - Safety Issues | Not applicable | Withdrawn | Swiss Transfusion SRC | 2024-01-01 | 2024-03-15 | |
| Hepatitis B Vaccination After Neonatal Surgery Vaccination Reaction, Hepatitis B Virus Infection | Recruiting | Children's Hospital of Chongqing Medical University | 180 | 2022-11-01 | 2023-09-11 | |
| Transfusion Surveillance in Anaesthesia Transfusion - Transfusion Reaction, Transfusion Related Complication | Recruiting | Erasme University Hospital | 50000 | 2022-09-01 | 2025-09-02 | |
| Enhanced Recovery and Patient Blood Management in Colorectal Surgery Colorectal resection - Anastomotic Leak, Colorectal Neoplasms | Unknown | Ospedale Sandro Pertini, Roma | 5000 | 2022-07-01 | 2023-11-02 | |
| Anticoagulant/Antiaggregant Use and Postoperative Bleeding Risk in Patients With Bladder Tumor and Benign Prostatic Hyperplasia Hematuria, Retention, Urinary | Completed | Bezmialem Vakif University | 500 | 2022-03-10 | 2023-07-28 | |
| Blood Transfusion Education Using Blended Virtual Reality and Simulation for Nursing Undergraduate Students Evidence-based VR simulation - Blood Transfusion Complication | Not applicable | Completed | The University of Hong Kong | 151 | 2022-03-01 | 2023-06-28 |
| Blood Warming in Preterm Infants to Decrease Hypothermia Ranger blood warmer (3M Healthcare, Oakdale, Minnesota) - Preterm Birth, Blood Transfusion Complication | Not applicable | Recruiting | University of South Carolina | 140 | 2022-01-01 | 2024-12-11 |
| UltraMTP in Adult Trauma Patients Undergoing Surgery Within 24 Hours: Effects on Mortality and Clinical Outcomes Blood transfusion - Trauma, Blood Transfusion Complication | Completed | University of Southern California | 3000 | 2021-08-15 | 2024-03-05 | |
| ABTEST© Card Clinical Perfomance Study ABTEST card - Transfusion Reaction | Not applicable | Completed | Diagast | 100 | 2021-06-06 | 2021-12-01 |
| Perioperative Outcomes of Postpartum Hemorrhage in Patients Undergoing Cesarean Delivery Cesarean Section Complications, Postpartum Hemorrhage | Completed | Mahidol University | 649 | 2021-04-22 | 2025-12-22 |
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Transfusion-Related Acute Lung Injury (12) · Anemia (4) · Hemorrhage (4) · Gastrointestinal Hemorrhage (3) · Hypersensitivity (3) · Respiratory Distress Syndrome (3) · Acute Kidney Injury (2) · Acute Lung Injury (2) · Heart Defects, Congenital (2) · Hemostatic Disorders (2) · Hip Fractures (2) · Premature Birth (2) · Shock (2) · Thrombosis (2)
Hematologic Diseases (62) · Hemic and Lymphatic Diseases (62) · Immune System Diseases (62) · Pathological Conditions, Signs and Symptoms (16) · Lung Diseases (13) · Respiratory Tract Diseases (13) · Lung Injury (12) · Pathologic Processes (12) · Acute Lung Injury (10) · Digestive System Diseases (7) · Cardiovascular Diseases (6) · Female Urogenital Diseases and Pregnancy Complications (6) · Urogenital Diseases (6) · Gastrointestinal Diseases (5)
Blood Transfusion (7) · Saline Solution (2) · Ascorbic Acid (1) · Basophil Degranulation Test (1) · Blood Specimen Collection (1) · Blood Transfusion, Autologous (1) · Chlorpheniramine (1) · Colectomy (1) · Factor IX (1) · Fibrinogen (1) · Furosemide (1) · Liver Transplantation (1) · Phlebotomy (1) · Platelet Transfusion (1) · Proctectomy (1)
The Third Xiangya Hospital of Central South University (4) · Diagast (3) · National Institutes of Health Clinical Center (CC) (3) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (2) · Cerus Corporation (2) · Haukeland University Hospital (2) · Swiss Transfusion SRC (2) · University of Colorado, Denver (2) · Bezmialem Vakif University (1) · Centre Hospitalier Universitaire Vaudois (1) · Centre Hospitalier Universitaire de Besancon (1) · Children's Hospital of Chongqing Medical University (1) · Damanhour University (1) · Damascus University (1) · Erasme University Hospital (1)
United States (16) · China (7) · Italy (5) · Canada (4) · Egypt (3) · France (3) · Netherlands (3) · Turkey (Türkiye) (3) · Belgium (2) · Norway (2) · United Kingdom (2) · Hong Kong (1) · Ireland (1) · Israel (1) · Switzerland (1)
Torunn O Apelseth, MD, PhD (2) · Abdullah Ilktac, MD (1) · Alexander Vlaar, MD PhD MBA (1) · Alexander Vlaar, Professor (1) · Amira B Kassem, PHD (1) · Anthony Gallagher, PhD (1) · Beth Shaz, M.D. (1) · Catherine M Kuza, MD (1) · Christine M Csert-Gazdewich, MD (1) · Daryl Kor, MD (1) · David F Stroncek, M.D. (1) · Edward L Snyder, MD (1) · Eugene Oteng-Ntim (1)
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U01HL077863 (1)