2 completed, 1 not yet recruiting, 1 terminated, 1 unknown. 5 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 2, Not yet recruiting 1, Terminated 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
Follow Transfusion Reaction: new trials by email Literature Review of Transfusion Reaction trials Research Report on Transfusion Reaction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Challenge Transfusion of INTERCEPT Pathogen Reduced Red Blood Cells (RBCs) in Subjects With or Without Pre-existing Antibodies to INTERCEPT RBCs 30-40 mL of INTERCEPT RBCs, ~30 mL of INTERCEPT RBCs plus plus 10 mL biotinylated INTERCEPT RBCs - Transfusion Reaction, Hemolytic | Phase 2 | Not yet recruiting | Cerus Corporation | 25 | 2026-10-10 | 2026-10-14 |
| ZEPLAST- PED: ZEro_PLASma Trial in Small Infants Undergoing Cardiac Surgery Fibrinogen Concentrate Human, Prothrombin Complex Concentrate, Fresh Frozen Plasma - Bleeding, Cardiac Defect | Phase 2 | Terminated | IRCCS Policlinico S. Donato | 40 | 2020-02-27 | 2021-11-03 |
| Role of Ascorbic Acid Infusion in Critically Ill Patients With Transfusion Related Acute Lung Injury Ascorbic Acid Injectable Product, Placebo - Acute Lung Injury, Transfusion Related | Phase 2 | Completed | Damanhour University | 40 | 2019-11-30 | 2023-07-19 |
| TAPS2 Transfusion Antenatally in Pregnant Women With SCD Serial prophylactic exchange blood transfusion (SPEBT). - Sickle Cell Disease, Pregnancy, High Risk | Phase 2 | Unknown | Guy's and St Thomas' NHS Foundation Trust | 50 | 2019-05-02 | 2019-08-02 |
| Point-of-Care RBC Washing to Prevent Transfusion-Related Pulmonary Complications Point-of-care washed red blood cell transfusion., Standard of care red blood cell transfusion. - Blood Transfusion Complications | Phase 1 / Phase 2 | Completed | Mayo Clinic | 171 | 2016-01-01 | 2021-04-06 |
Transfusion-Related Acute Lung Injury (3) · Acute Lung Injury (1) · Afibrinogenemia (1) · Anemia, Sickle Cell (1) · Heart Defects, Congenital (1) · Hemophilia B (1) · Hemorrhage (1)
Hematologic Diseases (5) · Hemic and Lymphatic Diseases (5) · Immune System Diseases (5) · Lung Diseases (3) · Lung Injury (3) · Respiratory Tract Diseases (3) · Acute Lung Injury (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Genetic Diseases, Inborn (2) · Anemia (1) · Anemia, Hemolytic (1) · Anemia, Hemolytic, Congenital (1) · Blood Coagulation Disorders (1) · Blood Coagulation Disorders, Inherited (1) · Cardiovascular Abnormalities (1)
Ascorbic Acid (1) · Factor IX (1) · Fibrinogen (1) · Saline Solution (1)
Cerus Corporation (1) · Damanhour University (1) · Guy's and St Thomas' NHS Foundation Trust (1) · IRCCS Policlinico S. Donato (1) · Mayo Clinic (1)
United States (2) · Egypt (1) · Italy (1) · United Kingdom (1)
Amira B Kassem, PHD (1) · Daryl Kor, MD (1) · Eugene Oteng-Ntim (1) · Gamal A Omran, PHD (1) · Islam E Ahmed, PharmD (1) · Marco Ranucci, MD (1) · Mohamed M Megahed, MD (1) · Tamer N Zakhary, MD (1)
PMID 28821525, PMID 32312326, PMID 34866234, PMID 36408876, PMID 38954844