6 recruiting, 5 completed, 3 active not recruiting, 2 not yet recruiting. 10 Not applicable, 3 Early Phase 1, 1 Phase 1, 1 Phase 2.
Follow Tooth Extraction Site Healing: new trials by email Literature Review of Tooth Extraction Site Healing trials Research Report on Tooth Extraction Site Healing
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Volumetric Efficacy of Alveolar Ridge Preservation Spontaneous Healing, d-PTFE Membrane, Leukocyte- and Platelet-Rich Fibrin (L-PRF) - Alveolar Ridge Preservation, Tooth Loss | Not applicable | Recruiting | Universidad del Desarrollo | 70 | 2026-09-15 | 2026-09-10 |
| Biomaterials Exposed to Oral Environment: Which One is the Appropriate Option? Alveolar Ridge Reconstruction - Tooth Extraction Site Healing, Alveolar Ridge Preservation | Not applicable | Enrolling by invitation | Pontificia Universidade Católica do Rio Grande do Sul | 60 | 2026-05-05 | 2026-09-17 |
| Effect of a Bioactive Mineral-Ionic Mouthrinse on Periodontal Soft Tissue Healing Normal Saline, chlorhexidine (CHX), Theravex Bioactive Solutions (Tissue Care Plus and Oral) - Tooth Extraction Site Healing | Not applicable | Completed | Biointelligent Technology Systems SL | 94 | 2026-04-28 | 2026-05-29 |
| Wound Healing Following Extraction and Ridge Preservation in Smokers and Non-smokers observational study - Smoking, Cigarette, Alveolar Bone Grafting | Not yet recruiting | Marquette University | 12 | 2026-01-25 | 2026-01-28 | |
| Assessment of the Impact of Neocement Inject P® (Beta-Tricalcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction Neocement Inject P® (Beta-Tricalcium Phosphate) - Tooth Extraction, Tooth Extraction Site Healing | Early Phase 1 | Recruiting | Egas Moniz - Cooperativa de Ensino Superior, CRL | 30 | 2025-12-01 | 2026-06-11 |
| Improving Healing in Children After Tooth Extraction Using Laser Therapy or Hyaluronic Acid Low-Level Laser Therapy, Hyaluronic Acid (HA) - Mesh, Healthy Volunteer | Not applicable | Not yet recruiting | Cairo University | 36 | 2025-12-01 | 2025-10-03 |
| Assessment of the Impact of Neobone® (Biphasic Calcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction Neobone® (Biphasic Calcium Phosphate) - Tooth Extraction Site Healing, Alveolar Ridge Preservation | Early Phase 1 | Recruiting | Egas Moniz - Cooperativa de Ensino Superior, CRL | 30 | 2025-12-01 | 2026-06-11 |
| Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva Low-level laser therapy - Wound Healing and Prevention, Oral Inflammation | Not applicable | Recruiting | Medical University of South Carolina | 39 | 2025-11-05 | 2025-11-12 |
| Determinants of Bone Dimensional Changes After Extraction and Alveolar Ridge Preservation observational study - Alveolar Bone Grafting, Bone Healing | Recruiting | Marquette University | 160 | 2025-10-08 | 2025-11-17 | |
| Efficacy of Albumin Platelet Rich Fibrin on Complications After Mandibular Third Molar Extraction. Alb-PRF Autologous Albumin Gel, Surgical extraction of impacted third molar - Tooth Extraction Site Healing | Not applicable | Completed | Mansoura University | 16 | 2025-09-20 | 2026-04-21 |
| Safety and Performance, and Dose, of OsteoAdapt DE in Localized Alveolar Ridge Augmentations OsteoAdapt DE (0.8 mg), OsteoAdapt DE (2.0 mg), Xenograft Bone Graft - Tooth Extraction Site Healing, Ridge Augmentation | Phase 1 / Phase 2 | Active not recruiting | Theradaptive, Inc | 45 | 2025-07-17 | 2026-04-06 |
| Socket Preservation Using Autogenous Dentin Tooth extraction left to heal spontaneously, Tooth extraction plus collagen sponge, Tooth extraction plus tricalcium phosphate - Tooth Extraction Site Healing | Not applicable | Recruiting | University of Ostrava | 80 | 2025-01-01 | 2026-05-27 |
| Autogenous Tooth Bone Graft for Alveolar Socket Preservation "Autogenous Tooth Bone Graft" - Alveolar Bone Grafting, Bone Regeneration Following Wisdom Teeth Extraction | Not applicable | Active not recruiting | Haifaa Mohammed Al-hussini | 20 | 2024-07-14 | 2025-12-05 |
| Effect of Injectable Platelet Rich Fibrin (i-PRF) on Extraction Socket Healing: A Split-Mouth Randomized Study. Surgical extraction of lower third molars. - Wound Healing, Tooth Extraction Site Healing | Not applicable | Completed | Saglik Bilimleri Universitesi | 32 | 2024-05-01 | 2025-12-02 |
| Comparison of Intraligamentary Anesthesia With the Inferior Alveolar Nerve Block for the Extraction of Mandibular Molars. Intraligamentary anaesthesia, Inferior alveolar nerve block - Tooth Extraction, Tooth Extraction Site Healing | Not applicable | Completed | Hamza Zia Ahmed | 535 | 2024-03-15 | 2024-09-25 |
| Alveolar Ridge Preservation With Cortico-cancellous Porcine Bone tooth extraction with alveolar ridge preservation, Implant placement - Alveolar Ridge Preservation, Implant Therapy | Active not recruiting | University of Pisa | 22 | 2021-06-15 | 2025-05-20 | |
| Topical Analgesic Versus Saline Mouth Rinses in Post Extraction Healing Aspirin Powder, Normal saline - Tooth Extraction Site Healing | Early Phase 1 | Completed | Aga Khan University | 60 | 2016-01-01 | 2018-06-28 |
Alveolar Bone Loss (1) · Cigarette Smoking (1) · Dry Socket (1) · Inflammation (1) · Pain, Postoperative (1) · Periodontal Diseases (1) · Tooth Loss (1)
Mouth Diseases (4) · Stomatognathic Diseases (4) · Periodontal Diseases (2) · Behavior (1) · Bone Diseases (1) · Bone Resorption (1) · Musculoskeletal Diseases (1) · Neurologic Manifestations (1) · Pain (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1) · Periodontal Atrophy (1) · Postoperative Complications (1) · Signs and Symptoms (1) · Smoking (1)
Low-Level Light Therapy (2) · Observation (2) · Saline Solution (2) · Tooth Extraction (2) · Chlorhexidine (1) · Hyaluronic Acid (1) · Leukocyte Count (1) · Sodium Chloride (1) · tricalcium phosphate (1)
Egas Moniz - Cooperativa de Ensino Superior, CRL (2) · Marquette University (2) · Aga Khan University (1) · Biointelligent Technology Systems SL (1) · Cairo University (1) · Haifaa Mohammed Al-hussini (1) · Hamza Zia Ahmed (1) · Mansoura University (1) · Medical University of South Carolina (1) · Pontificia Universidade Católica do Rio Grande do Sul (1) · Saglik Bilimleri Universitesi (1) · Theradaptive, Inc (1) · Universidad del Desarrollo (1) · University of Ostrava (1) · University of Pisa (1)
United States (3) · Egypt (2) · Pakistan (2) · Portugal (2) · Armenia (1) · Brazil (1) · Chile (1) · Czechia (1) · Israel (1) · Italy (1) · Saudi Arabia (1) · Turkey (Türkiye) (1) · Yemen (1)
Vrisiis Kofina, DDS, MS (2) · Amjad Bari, MDS (1) · Claudio M Miranda, dds (1) · Dusan M Marinkovic, DDS (1) · Farhan R Khan, BDS MS FCPS (1) · Haifaa Alhussini, BDS, MSc (1) · Martin Starosta, Assoc. Prof. (1) · Mona Ali Abd Elhafiz, BDS (1) · Pinar Emecen-Huja (1)