86 completed, 45 unknown, 28 recruiting, 13 not yet recruiting. 65 Not applicable, 10 Phase 3, 8 Phase 2, 7 Phase 4, 4 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Right Heart and Lung Blood Flow During Exercise (RIGHT-NET 2.0) Right Ventricular Dysfunction, Cardiopulmonary Diseases | Not yet recruiting | IRCCS SYNLAB SDN | 2000 | 2027-01-01 | 2026-10-01 | |
| Stromal Desmoplastic Reaction as a Predictive Factor for Lymph Node Metastasis in Medullary Thyroid Cancer lobectomy with lymph node dissection - Medullary Thyroid Carcinoma | Not yet recruiting | Aristotle University Of Thessaloniki | 74 | 2026-09-30 | 2026-10-01 | |
| Alpelisib Challenge Test (ACT) Alpelisib 300 mg, Alpelisib Challenge Test (ACT): Mixed Meal Tolerance Test (MMTT) after taking alpelisib, Hyperglycemic clamp - Insulin Resistance, Type 2 Diabetes | Phase 1 | Recruiting | Columbia University | 15 | 2026-09-02 | 2026-09-03 |
| Can Exercise Electrocardiography Discriminate Hypertensive Heart Disease From Obstructive Coronary Artery Disease? A Multimodality Imaging Study Obstructive Coronary Artery Disease, Left Ventricular Hypertrophy | Recruiting | University of Pisa | 30 | 2026-09-01 | 2026-09-29 | |
| Efficacy of a Bilateral Robotic Treatment in Chronic Patients Bilateral robotic treatment for the upper limbs, Standard physiotherapy - Stroke | Not applicable | Not yet recruiting | University of Pisa | 60 | 2026-07-01 | 2026-04-28 |
| Evaluation of the Impact of Virtual Park on Training Motivation in Adult Patients Dual-task training with Virtual Reality, Cycling training - Post-stroke, Parkinson Disease | Not applicable | Not yet recruiting | Marta Mondellini | 70 | 2026-06-01 | 2026-05-29 |
| Alter-Ego as an Assistive Robotic Device. Amyotrophic Lateral Sclerosis, Health Adult Subjects | Not yet recruiting | University of Pisa | 52 | 2026-05-01 | 2026-05-07 | |
| PACE Study: School-Based Mindfulness and Compassion Interventions for Children Mindfulness-based intervention, Social Emotional Learning Program, Compassion-focused Training - School-based Intervention, Mindfulness-based Intervention | Not applicable | Recruiting | IRCCS Fondazione Stella Maris | 500 | 2026-04-13 | 2026-03-19 |
| Virtual Twins as Tools for Personalized Clinical Care in Renal Denervation - Pilot Study Data collection in order to train the digital twin - Hypertension | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 60 | 2026-04-01 | 2026-03-10 | |
| Oral Biopsy Bleeding in Patients on Direct Oral Anticoagulants (DOACs) Direct Oral Anticoagulants (DOACs), Oral Surgical Procedures | Recruiting | University of Pisa | 100 | 2026-04-01 | 2026-04-09 | |
| Team-Based Learning Integrated Into Clinical Simulation in Nursing Students Team-Based Learning Integrated Clinical Simulation, Traditional Clinical Simulation - Nursing Education | Not applicable | Not yet recruiting | University of Pisa | 150 | 2026-03-01 | 2026-03-17 |
| Evaluation of a Multimodal Tactile Feedback System for Upper Limb-loss Users: Embodiment and Performance Pressure and vibrotactile feedbak, Pressure feedback, Vibrotactile feedback - Amputees | Not applicable | Recruiting | University of Pisa | 9 | 2026-01-09 | 2026-02-18 |
| Effects of Statins and Hormone Replacement Therapy in Coagulation Profile of Menopausal Women With Dyslipidemia estroprogestins, Statin - Menopausal Complaints, Hypercholerolemia | Recruiting | University of Pisa | 70 | 2025-10-15 | 2026-08-03 | |
| Genetic and Clinical Correlates of Disruptive Behavior Disorder With and Without Callous-Unemotional Traits Conduct Disorder, Oppositional Defiant Disorder | Active not recruiting | IRCCS Fondazione Stella Maris | 200 | 2025-10-07 | 2026-01-26 | |
| Nicotinamide Levels in Serum, Aqueous Humor, and Tear Film in Glaucoma and Correlations With Mitochondrial Damage-Associated Molecular Patterns (mtDAMPs) and Senescence-Associated Secretory Phenotype (SASP) Nicotinamide Tablet - Glaucoma | Not applicable | Not yet recruiting | Università degli Studi 'G. d'Annunzio' Chieti e Pescara | 360 | 2025-10-01 | 2025-06-05 |
| Validation of Energy Expenditure Measures Study Obesity Prevention, Healthy | Recruiting | University of Leipzig | 49 | 2025-08-26 | 2026-09-14 | |
| 24-h Energy Expenditure and Anti-obesity Medication anti obesity medication - Obesity | Enrolling by invitation | University of Pisa | 30 | 2025-07-01 | 2026-05-05 | |
| Sarcopenia in Gestational Diabetes Sarcopenia tests (for muscle mass, muscle function, physical performance), Oral Glucose Tolerance Test, Montreal Cognitive Assessment - Sarcopenia, Gestational Diabetes Mellitus (GDM) | Recruiting | Istituto di Neuroscienze Consiglio Nazionale delle Ricerche | 200 | 2025-05-28 | 2025-11-21 | |
| Assessing Intellectual and Motor Outcomes in High-risk Infants Cerebral Palsy, Cerebral Palsy (CP) | Recruiting | University College Cork | 600 | 2025-03-21 | 2026-05-13 | |
| Closed-System Bladder Irrigation to Reduce Urinary Tract Infections After Endoscopic Urologic Surgery (IRIS Trial) Closed-System Bladder Irrigation Flow Switch Device, Standard Bladder Irrigation - Urinary Tract Infection Bacterial, Benign Prostatic Hyperplasia | Not applicable | Completed | University of Pisa | 240 | 2025-02-01 | 2026-04-03 |
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Graves Ophthalmopathy (11) · Obesity (10) · Cerebral Palsy (9) · Diabetes Mellitus, Type 2 (8) · Periodontal Diseases (7) · Periodontitis (7) · Insulin Resistance (5) · Heart Failure (4) · Pancreatic Neoplasms (4) · Wounds and Injuries (4) · Breast Neoplasms (3) · Ciliary Motility Disorders (3) · Cognitive Dysfunction (3) · Colonic Neoplasms (3) · Diabetes Mellitus (3)
Methylprednisolone (4) · Root Planing (4) · dapagliflozin (3) · Atorvastatin (2) · Electrocardiography (2) · Hydroxymethylglutaryl-CoA Reductase Inhibitors (2) · Iodine-131 (2) · Methimazole (2) · Sirolimus (2) · Tooth Exfoliation (2) · empagliflozin (2) · saxagliptin (2) · 4-amino-4'-hydroxylaminodiphenylsulfone (1) · Abciximab (1) · Alpelisib (1)
Italy (142) · Germany (8) · United States (7) · Spain (5) · France (4) · Austria (3) · Switzerland (3) · United Kingdom (3) · Belgium (2) · Portugal (2) · Greece (1) · Hungary (1) · Ireland (1) · Netherlands (1) · Romania (1)
Anna Solini, MD, PhD (6) · Natalia Maximova, MD (4) · Filippo Graziani, DDS, PhD (3) · Guido Bocci, MD, PhD (3) · Joshua R Cook, MD, PhD (3) · Stefano Del Prato, MD (3) · Andrea Poli, Psy.D. (2) · Karen L. Andrews, M.D. (2) · Nicola Pagnucci, RN, MSN, PhD (2) · Adamasco Cupisti, MD, PhD (1) · Alberto Piaggesi, Doctor (1) · Alessandro Ventura, MD (1) · Alessandro Zucchi, Professor (1)
PMID 20618550, PMID 11159059, PMID 12795787, PMID 15161421, PMID 16049943, PMID 16307569, PMID 1647413, PMID 17915573, PMID 18723240, PMID 19203740, PMID 19220406, PMID 19269895, PMID 19419444, PMID 19541547, PMID 20238325, PMID 20411900, PMID 20546085, PMID 20830598, PMID 2099210, PMID 21491763, PMID 21689019, PMID 21786296, PMID 21932013, PMID 22392031, PMID 22471941, PMID 22531139, PMID 22582745, PMID 22843083, PMID 23062125, PMID 23151314, PMID 23151831, PMID 23257370, PMID 23539736, PMID 23612465, PMID 23705111, PMID 23881919, PMID 24022110, PMID 24146165, PMID 24281461, PMID 24589344, PMID 24589908, PMID 24993976, PMID 25101284, PMID 25180278, PMID 25256816, PMID 25391139, PMID 25501898, PMID 25521357, PMID 26343356, PMID 26411871
K23DK140614 (1)