50 completed, 38 unknown, 9 recruiting, 6 active not recruiting. 92 Not applicable, 8 Phase 2, 2 Phase 1, 2 Phase 3, 2 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Evaluation of Two Post Systems for Single Crown Restoration of Anterior Teeth Custom-Fit UHMWPE Fiber Post with Composite Core - Cairo University, Nonvital Tooth | Not applicable | Not yet recruiting | Cairo University | 84 | 2026-10-02 | 2026-10-20 |
| Predictable Method for Restoring Endodontically Treated Teeth, Comparing Indirect and Direct Methods and Materials in Aesthetic Dentistry. Cementation with Panavia V5, Cementation with Panavia SA, Injection moulding - Endodontically Treated Teeth Requiring Indirect Restorative Treatment | Not applicable | Not yet recruiting | Riga Stradins University | 30 | 2026-08-18 | 2026-08-21 |
| Bite Force and Occlusal Force Distribution Following Root Canal Treatment. Endodontically Treated Teeth | Not yet recruiting | Chulalongkorn University | 70 | 2026-06-08 | 2026-06-04 | |
| Additive vs Subtractive Manufacturing for Endocrown Fabrication: A 24-Month RCT CAD/CAM Milled HC Hard Block Endocrown, 3D-Printed VarseoSmile TriniQ Endocrown - Tooth, Nonvital, Dental Restoration | Not applicable | Not yet recruiting | Cairo University | 60 | 2026-06-01 | 2026-06-08 |
| Milled vs 3D-Printed Partial-Coverage Restorations in Endodontically Treated Molars Milled Composite Resin Onlay/Overlay Restoration, 3D-Printed Composite Resin Onlay/Overlay Restoration - Endodontically Treated Teeth | Not applicable | Recruiting | Hospital San Jose | 142 | 2026-05-29 | 2026-06-11 |
| Deep Margin Elevation in Endodontically Treated Posterior Teeth Deep Margin Elevation, CAD/CAM Restoration Without DME - Periodontal Health, Endodontically Treated Teeth | Not applicable | Active not recruiting | Hacettepe University | 45 | 2026-03-24 | 2026-07-02 |
| Antimicrobial Photodynamic Therapy in the Endodontic Treatment of Anterior Primary Teeth With Pulp Necrosis Conventional Endodontic Treatment, Antimicrobial Photodynamic Therapy - Dental Pulp Necroses, Tooth, Nonvital | Not applicable | Completed | University of Nove de Julho | 7 | 2025-11-01 | 2026-09-16 |
| Clinical Comparison of Lithium Disilicate and 3D-Printed Resin Endocrowns IPS e.max CAD Lithium Disilicate Endocrown, BEGO VarseoSmile TriniQ Resin Endocrown - Endodontically Treated Teeth, Nonvital Teeth | Not applicable | Active not recruiting | Medipol University | 60 | 2025-10-08 | 2026-10-15 |
| Conservative Versus Conventional Restorative Approach for Endodontically Treated Posterior Teeth Fiber reinforced composite core and an overlay, Fiber post with composite core build up and lithium disilicate full coverage crown - Root Canal Treated Posterior Teeth, Endodontically-Treated Teeth | Not applicable | Recruiting | Moataz Mostafa Anwar | 50 | 2025-09-20 | 2026-10-06 |
| Comparison of the Clinical Performance of High Strength Hybrid Ceramic Indirect Restorations Cemented on Endodontically Treated Teeth Using Bioactive Versus Conventional Self Adhesive Resin Cements. Resin Cement - Endodontically Treated Molar | Not applicable | Not yet recruiting | Cairo University | 50 | 2025-06-23 | 2025-06-10 |
| Clinical Success of Onlays Fabricated With Different Types of Resin Saremco print resin, Varseosmile Crownplus resin, Varseosmile TriniQ resin - Endodontically-Treated Teeth | Not applicable | Recruiting | Mersin University | 48 | 2025-06-18 | 2025-09-10 |
| Post Operative Sensitivity of MTA Obturation MTA - Dental Pulp Disease, Endodontically Treated Teeth | Completed | TC Erciyes University | 54 | 2025-01-30 | 2026-01-02 | |
| Clinical Performance of Printed Hybrid Resin in Indirect Restorations Indirect adhesive overlay restoration, Enamel Plus HRi, RelyX Universal - Endodontically Treated Teeth, Indirect Restoration | Not applicable | Recruiting | Universitat Internacional de Catalunya | 60 | 2024-12-13 | 2026-03-16 |
| Multiple-Visit RCT in Teeth With SAP: Interappointment Dressing or Not? Ca(OH)2 as intracanal medicament - Endodontically Treated Teeth, Calcium Hydroxide | Not applicable | Active not recruiting | Aristotle University Of Thessaloniki | 110 | 2024-09-12 | 2026-06-15 |
| Digital, Conventional, And Biomimetic Approaches for Restoring Endodontically Treated Teeth EverX Posterior - Endodontically Treated Teeth | Not applicable | Recruiting | October University for Modern Sciences and Arts | 42 | 2024-09-01 | 2024-12-16 |
| Shade Matching and Patient Satisfaction of Yttria Stabilized Multilayered Zirconia and Lithium Disilicate Restorations Yttria stabilized multilayered (YML) zirconia restorations, Lithium disilicate restorations - Mutilated Teeth, Endodontically Treated Teeth | Not applicable | Completed | Cairo University | 22 | 2024-09-01 | 2026-10-21 |
| Effectiveness of GentleWave System in Endodontic Treatment GentleWave, Conventional Protocol - Pain, Postoperative, Root Canal Infection | Not applicable | Unknown | University of Salamanca | 70 | 2024-08-20 | 2024-08-21 |
| Effect of Photobiomodulation on Pain and Healing of the Vertical Releasing Incision After Endodontic Microsurgery PBM treatment, PBM sham treatment, EMS - Apical Periodontitis, Endodontically Treated Teeth | Not applicable | Recruiting | The University of Texas Health Science Center, Houston | 90 | 2024-08-20 | 2026-08-17 |
| No Code Artificial Intelligence to Detect Radiographic Features Associated With Unsatisfactory Endodontic Treatment AI guidance for finding radiographic features - Endodontically Treated Teeth, Endodontic Underfill | Not applicable | Unknown | University of Copenhagen | 80 | 2024-07-30 | 2024-06-25 |
| The Performance of Posterior Partial Coverage Coronal Restorations Luted With Two Differrent Systems. IPS Empress Direct, Bisco Duo-Link Universal - Unsatisfactory or Defective Restoration of Tooth | Not applicable | Recruiting | King Abdullah University Hospital | 70 | 2024-05-01 | 2025-03-14 |
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Pain, Postoperative (14) · Dental Pulp Diseases (7) · Periapical Periodontitis (6) · Dental Caries (5) · Tooth Abnormalities (4) · Dental Pulp Necrosis (3) · Tooth Attrition (3) · Tooth Discoloration (3) · Tooth Injuries (3) · Anodontia (2) · Periapical Diseases (2) · Periapical Granuloma (2) · Tooth Fractures (2) · Agnosia (1)
Stomatognathic Diseases (111) · Tooth Diseases (111) · Dental Pulp Diseases (104) · Pathological Conditions, Signs and Symptoms (20) · Pathologic Processes (19) · Neurologic Manifestations (15) · Pain (15) · Signs and Symptoms (15) · Postoperative Complications (14) · Mouth Diseases (9) · Periodontal Diseases (9) · Jaw Diseases (8) · Periodontitis (8) · Periapical Diseases (6) · Congenital Abnormalities (5)
Endodontics (3) · Cryotherapy (2) · Lasers, Semiconductor (2) · Low-Level Light Therapy (2) · Pemetrexed (2) · Root Canal Obturation (2) · formocresol (2) · Anesthesia, Local (1) · Cementation (1) · Composite Resins (1) · Control Groups (1) · Crowns (1) · Dental Impression Technique (1) · Dental Occlusion (1) · Dry Needling (1)
Cairo University (29) · Federal University of Pelotas (5) · Istanbul Medipol University Hospital (4) · Ain Shams University (3) · Cukurova University (2) · Hacettepe University (2) · Okan University (2) · Universitat Internacional de Catalunya (2) · University of Bologna (2) · University of Health Sciences Lahore (2) · University of Nove de Julho (2) · University of Sao Paulo (2) · Abant Izzet Baysal University (1) · Afyonkarahisar Health Sciences University (1) · Ajman University (1)
Egypt (29) · Turkey (Türkiye) (19) · Brazil (12) · Spain (4) · United States (4) · Pakistan (3) · Jordan (2) · Chile (1) · France (1) · Germany (1) · Greece (1) · Iran (1) · Israel (1) · Italy (1) · Serbia (1)
Keziban Olcay, DDS, Phd (2) · Shazia Naz, BDS, MDS (2) · Abeer Darrag, Phd (1) · Abeer H Mahran, professor (1) · Alexis Gaudin, MD (1) · Amnon Singer, DMD (1) · Angie Ghoneim, PHD (1) · Anna Carolina RT Horliana (1) · Anne-Margaux Collignon, MD (1) · Ashraf M Zaazou, PhD (1) · Asmaa FE Mohamed, B.D.S (1) · Brigitte Grosgogeat, MD, PhD (1) · Carmela Bresolin (1)
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