5 completed. 5 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Completed 5 |
Follow Syphilis: new trials by email Literature Review of Syphilis trials Research Report on Syphilis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Trial of Doxycycline VS BPG for Early Syphilis (SY-DOXY) BPG, Doxycycline - Syphilis | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 200 | 2021-12-06 | 2025-11-20 |
| Alternative Antibiotics for Syphilis Linezolid 600 mg (post-interim), Benzathine Penicilllin G (post-interim) - Early Latent Syphilis, Primary Syphilis | Phase 3 | Completed | Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia | 165 | 2021-10-14 | 2026-07-29 |
| Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases in Neurological Disorders in DRC Immunochromatographic HAT tests (DSD), Card Agglutination Trypanosoma Test, TB POC Nucleic Acid Amplification Test (Molbio Diagnostics) - Neurological Disorders, Cerebral Malaria | Phase 3 | Completed | Institute of Tropical Medicine, Belgium | 352 | 2012-09-01 | 2016-01-18 |
| Male Circumcision for HIV Prevention in Rakai, Uganda Adult male circumcision - HIV Infections, Herpesvirus 2, Human | Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 5000 | 2002-08-01 | 2007-08-24 |
| Azithromycin/Bicillin Syphilis Azithromycin, Benzathine Penicillin, Doxycycline - Syphilis | Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 593 | 2000-06-01 | 2013-04-29 |
Chancroid (1) · Genital Diseases, Male (1) · HIV Infections (1) · Malaria, Cerebral (1) · Meningitis, Bacterial (1) · Meningitis, Cryptococcal (1) · Neglected Diseases (1) · Nervous System Diseases (1) · Neurosyphilis (1) · Sexually Transmitted Diseases (1) · Syphilis, Latent (1) · Syphilis, primary (1) · Syphilis, secondary (1) · Treponemal Infections (1)
Bacterial Infections (5) · Bacterial Infections and Mycoses (5) · Gram-Negative Bacterial Infections (5) · Infections (5) · Spirochaetales Infections (5) · Communicable Diseases (4) · Genital Diseases (4) · Sexually Transmitted Diseases, Bacterial (4) · Treponemal Infections (4) · Urogenital Diseases (4) · Sexually Transmitted Diseases (3) · Disease Attributes (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Actinomycetales Infections (1)
Doxycycline (2) · Azithromycin (1) · Linezolid (1) · Penicillin G Benzathine (1)
National Institute of Allergy and Infectious Diseases (NIAID) (2) · Assistance Publique - Hôpitaux de Paris (1) · Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia (1) · Institute of Tropical Medicine, Belgium (1)
Democratic Republic of the Congo (1) · France (1) · Madagascar (1) · Spain (1) · Uganda (1) · United Kingdom (1) · United States (1)
Emmanuel Bottieau, MD (1) · Marleen Boelaert, MD, PhD (1) · Ronald H. Gray, MD (1)
PMID 17321311, PMID 17545184, PMID 18086100, PMID 18532873, PMID 19220138, PMID 19321868, PMID 19389002, PMID 19571722, PMID 19936044, PMID 20370483, PMID 20402591, PMID 21216000, PMID 21998287, PMID 22210632, PMID 26094162, PMID 38211601, PMID 38914204
2019 (1)