7 terminated. 7 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Terminated 7 |
| Phase 3 | 2 | Terminated 2 |
| Phase 1 | 1 | Terminated 1 |
Follow Stroke, Acute: new trials by email Literature Review of Stroke, Acute trials Research Report on Stroke, Acute
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Maimonides Minocycline in Stroke Study Minocycline - Stroke, Acute, Ischemic Stroke | Phase 2 / Phase 3 | Terminated | Maimonides Medical Center | 2 | 2023-11-01 | 2025-12-17 |
| Exploring the Effect of Lactate Administration After Ischemic Stroke on Brain Metabolism Lactate, Placebo - Stroke, Acute | Phase 2 | Terminated | Centre Hospitalier Universitaire Vaudois | 28 | 2021-08-05 | 2025-04-17 |
| Pioglitazone Treatment for Hyperglycemic Acute Ischemic Stroke Pioglitazone 45 mg, Placebo oral tablet - Stroke, Acute, Hyperglycemia | Phase 1 / Phase 2 | Terminated | Milton S. Hershey Medical Center | 1 | 2020-09-01 | 2022-09-15 |
| Efficacy and Safety of Trans Sodium Crocetinate (TSC) for Treatment of Suspected Stroke Trans-Sodium Crocetinate, Placebo - Stroke, Acute | Phase 2 | Terminated | Diffusion Pharmaceuticals Inc | 6 | 2019-08-22 | 2021-06-18 |
| Study of Human Placenta-derived Cells (PDA001) to Evaluate the Safety and Effectiveness for Patients With Ischemic Stroke Human Placenta-Derived Cells PDA001- (cenplacel-L), Placebo - Stroke, Acute, Middle Cerebral Artery Stroke | Phase 2 | Terminated | Celularity Incorporated | 44 | 2011-03-01 | 2018-03-01 |
| The Intravascular Cooling in the Treatment of Stroke 2/3 Trial hypothermia and anti-shivering treatment, Group1: IV t-PA and normothermia - Stroke, Acute | Phase 2 / Phase 3 | Terminated | University of California, San Diego | 120 | 2010-06-01 | 2017-04-05 |
| FRALYSE Trial: Comparison of the Classical Rt-PA Procedure With a Longer Procedure in Acute Ischemic Stroke DFIL, NINDS - Stroke, Acute | Phase 2 | Terminated | Hospices Civils de Lyon | 500 | 2001-09-01 | 2011-07-22 |
Stroke (7) · Ischemic Stroke (2) · Body Temperature Changes (1) · Brain Diseases (1) · Brain Infarction (1) · Brain Ischemia (1) · Cardiovascular Diseases (1) · Central Nervous System Diseases (1) · Cerebral Infarction (1) · Cerebrovascular Disorders (1) · Diabetes Mellitus (1) · Hemorrhagic Stroke (1) · Hyperglycemia (1) · Hypothermia (1) · Infarction, Middle Cerebral Artery (1)
Brain Diseases (6) · Cardiovascular Diseases (6) · Central Nervous System Diseases (6) · Cerebrovascular Disorders (6) · Nervous System Diseases (6) · Vascular Diseases (6) · Infarction (2) · Ischemia (2) · Necrosis (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Brain Infarction (1) · Brain Ischemia (1) · Cerebral Arterial Diseases (1) · Cerebral Infarction (1)
Cool-Down Exercise (1) · Lactic Acid (1) · Minocycline (1) · National Institute of Neurological Disorders and Stroke (U.S.) (1) · Pioglitazone (1) · trans-sodium crocetinate (1)
Celularity Incorporated (1) · Centre Hospitalier Universitaire Vaudois (1) · Diffusion Pharmaceuticals Inc (1) · Hospices Civils de Lyon (1) · Maimonides Medical Center (1) · Milton S. Hershey Medical Center (1) · University of California, San Diego (1)
United States (5) · Switzerland (2) · Austria (1) · France (1)
Andrew Southerland, MD (1) · James C. Grotta, MD (1) · Jeffrey Saver, MD (1) · Karen Johnston, MD (1) · Kerstin Bettermann, MD, PhD (1) · Lorenz Hirt, MD (1) · Monica E Luchi, MD (1) · Nerses Sanossian, MD (1) · Patrick D. Lyden, MD (1) · Thomas M. Hemmen, MD, PhD (1)
2019 (1), P50NS044148 (1), P50NS044227 (1)