6 terminated. 6 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Terminated 6 |
| Phase 2 | 2 | Terminated 2 |
Follow Status Epilepticus: new trials by email Literature Review of Status Epilepticus trials Research Report on Status Epilepticus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy Vatiquinone, Placebo - Mitochondrial Diseases, Drug Resistant Epilepsy | Phase 2 / Phase 3 | Terminated | PTC Therapeutics | 68 | 2020-09-28 | 2026-03-31 |
| Efficacy Study of Acetazolamide Versus Diazepam in Continuous Spike and Wave/Landau-Kleffner Syndrome Diazepam, Acetazolamide - Landau-Kleffner Syndrome, Status Epilepticus, Electrographic | Phase 2 / Phase 3 | Terminated | Mayo Clinic | 3 | 2016-09-01 | 2020-06-11 |
| Ketamine in Refractory Convulsive Status Epilepticus Ketamine - Status Epilepticus | Phase 3 | Terminated | Meyer Children's Hospital IRCCS | 57 | 2015-04-01 | 2020-10-08 |
| Clobazam Use in Epilepsia Partialis Continua - Pilot Study Clobazam, Clonazepam, Lorazepam - Epilepsia Partialis Continua, Kojewnikov's Epilepsy | Phase 3 | Terminated | The Cooper Health System | 7 | 2014-07-01 | 2018-05-09 |
| Randomized Trial Comparing 3 Routes of Delivering Lorazepam to Children. Lorazepam - Status Epilepticus, Convulsions | Phase 3 | Terminated | Kamuzu University of Health Sciences | 800 | 2006-06-01 | 2012-07-10 |
| Treatment of Refractory Status Epilepticus propofol, thiopental/pentobarbital - Status Epilepticus | Phase 3 | Terminated | Brigham and Women's Hospital | 23 | 2006-05-01 | 2013-04-09 |
Seizures (2) · Diffuse Cerebral Sclerosis of Schilder (1) · Drug Resistant Epilepsy (1) · Epilepsia Partialis Continua (1) · Epilepsy (1) · Epilepsy, Partial, Motor (1) · Landau-Kleffner Syndrome (1) · Leigh Disease (1) · MELAS Syndrome (1) · MERRF Syndrome (1) · Mitochondrial Diseases (1) · Mitochondrial encephalopathy (1) · Nerve Degeneration (1) · Pontocerebellar Hypoplasia Type 6 (1)
Nervous System Diseases (6) · Neurologic Manifestations (6) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (6) · Seizures (4) · Brain Diseases (3) · Central Nervous System Diseases (3) · Epilepsy (2) · Epileptic Syndromes (2) · Autoimmune Diseases (1) · Autoimmune Diseases of the Nervous System (1) · Brain Diseases, Metabolic (1) · Brain Diseases, Metabolic, Inborn (1) · Carbohydrate Metabolism, Inborn Errors (1) · Cardiovascular Diseases (1)
Lorazepam (2) · Acetazolamide (1) · Clobazam (1) · Clonazepam (1) · Diazepam (1) · Ketamine (1) · Pentobarbital (1) · Propofol (1) · Thiopental (1) · alpha-tocotrienol quinone (1)
Brigham and Women's Hospital (1) · Kamuzu University of Health Sciences (1) · Mayo Clinic (1) · Meyer Children's Hospital IRCCS (1) · PTC Therapeutics (1) · The Cooper Health System (1)
United States (4) · Italy (2) · Canada (1) · France (1) · Japan (1) · Malawi (1) · Poland (1) · Spain (1) · Sweden (1) · Switzerland (1) · United Kingdom (1)
Andrea O. Rossetti, MD (1) · Anna Rosati, MD, PhD (1) · Elizabeth Molyneux (1) · Katherine C. Nickels, M.D. (1) · Melissa Carran, MD (1) · Vinay Penematsa, MD (1)