8 recruiting. 8 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 8 | Recruiting 8 |
| Phase 2 | 3 | Recruiting 3 |
Follow Smoking Cessation: new trials by email Literature Review of Smoking Cessation trials Research Report on Smoking Cessation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Studying NMDA and Sigma-1 in Smoking Cessation Treatment (SUMMIT) AXS-05 (dextromethorphan-bupropion), Bupropion, Placebo - Smoking Cessation | Phase 3 | Recruiting | Axsome Therapeutics, Inc. | 705 | 2026-08-27 | 2026-11-06 |
| A Study Of Vagal Nerve Stimulation In Conjunction With NRT For Smoking Cessation Non-invasive vagus nerve stimulator plus nicotine replacement patches, nicotine replacement patches - Smoking Cessation | Phase 2 / Phase 3 | Recruiting | Mayo Clinic | 150 | 2026-06-04 | 2026-09-25 |
| Empowering Cessation ACS South Region Empowering Cessation for the ACS South - Smoking Cessation | Phase 2 / Phase 3 | Recruiting | University of Oklahoma | 400 | 2025-08-14 | 2026-05-11 |
| Tobacco Education and Lung Health Study (TEAL) Phone-based Tobacco Treatment, Nicotine Replacement, and Stepped Care Intervention, E-Referral to the Tobacco Quitline - Smoking Cessation | Phase 3 | Recruiting | Georgetown University | 1188 | 2024-02-22 | 2026-02-17 |
| V+PSF-M for Tobacco Cessation in HIV Care in India Varenicline, Positively Smoke Free Mobile (PSF-M), Standard Care - Human Immunodeficiency Virus, Smoking Cessation | Phase 3 | Recruiting | University of Colorado, Denver | 400 | 2024-01-02 | 2025-06-15 |
| Evaluating Smoking Cessation Interventions for PWH in South Africa Varenicline, Nicotine patch, Nicotine gum - Smoking Cessation, HIV | Phase 2 / Phase 3 | Recruiting | Johns Hopkins University | 660 | 2023-11-27 | 2026-10-19 |
| Improving Smoking Abstinence Outcomes in the African American Community Through Extended Treatment Bupropion - Smoking Cessation | Phase 3 | Recruiting | University of Kansas Medical Center | 500 | 2023-02-28 | 2026-02-23 |
| Aggressive Smoking Cessation Trial (ASAP) Combination Therapy Arm (Varenicline and Nicotine E-Cigarettes Plus Counseling), Varenicline Plus Counseling - Acute Coronary Syndrome, Cardiovascular Diseases | Phase 3 | Recruiting | Sir Mortimer B. Davis - Jewish General Hospital | 798 | 2023-02-02 | 2025-04-29 |
Smoking (2) · Acquired Immunodeficiency Syndrome (1) · Acute Coronary Syndrome (1) · Cardiovascular Diseases (1) · Tobacco Smoking (1) · Tobacco Use Disorder (1) · Vaping (1)
Behavior (8) · Health Behavior (8) · Smoking (2) · Blood-Borne Infections (1) · Chemically-Induced Disorders (1) · Communicable Diseases (1) · Genital Diseases (1) · HIV Infections (1) · Heart Diseases (1) · Immune System Diseases (1) · Immunologic Deficiency Syndromes (1) · Infections (1) · Lentivirus Infections (1) · Mental Disorders (1) · Myocardial Ischemia (1)
Varenicline (3) · Bupropion (2) · Nicotine Replacement Therapy (2) · Tobacco Use Cessation Devices (2) · Counseling (1) · Nicotine Chewing Gum (1) · Standard of Care (1)
Axsome Therapeutics, Inc. (1) · Georgetown University (1) · Johns Hopkins University (1) · Mayo Clinic (1) · Sir Mortimer B. Davis - Jewish General Hospital (1) · University of Colorado, Denver (1) · University of Kansas Medical Center (1) · University of Oklahoma (1)
United States (6) · Canada (1) · India (1) · South Africa (1)
Gina Kruse, MD (1) · Ivana T Croghan, PhD (1) · Jonathan E Golub, PhD MPH (1) · Julia McQuoid, PhD (1) · Lisa Sanderson Cox, PhD (1) · Neil Martison (1) · Ryan T Hurt, MD, PhD (1)
R21CA302802 (1), U01CA261614 (1), U01CA261626 (1)