7 completed, 4 recruiting, 4 unknown, 2 not yet recruiting. 11 Not applicable, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 6, Not yet recruiting 2, Recruiting 1, Unknown 1, Withdrawn 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Terminated 1 |
Follow Skull Base Neoplasms: new trials by email Literature Review of Skull Base Neoplasms trials Research Report on Skull Base Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Surgical Outcomes of Extended Endoscopic Endonasal Approach for Skull Base Lesions. Endoscopic Endonasal Approach for Skull Base Lesions. - Skull Base Neoplasms | Not applicable | Not yet recruiting | Assiut University | 30 | 2026-09-01 | 2026-08-26 |
| Postoperative Complications Following Skull Base Tumor Resection Pulmonary ultrasound examination - Skull Base Tumor, Postoperative Complications | Recruiting | Beijing Tiantan Hospital | 122 | 2024-09-10 | 2025-02-14 | |
| Optic Nerve Stimulation To Prevent Visual Deficits After Endoscopic Cranial Approaches Optic Nerve Stimulation - Optic Nerve Injuries, Sellar Tumor | Not applicable | Not yet recruiting | University of California, San Francisco | 20 | 2024-08-01 | 2024-07-12 |
| ICG Angiogram as a Predictor of Postoperative Visual Function After EEA Surgery Indocyanine Green - Indocyanine Green, Skull Base Neoplasms | Unknown | University of California, San Francisco | 40 | 2024-07-01 | 2024-07-22 | |
| Role of Novel RADA16 Hydrogel in Endoscopic Skull Base Surgery Non-Absorbable Packing (Silastic Splint), PuraGel (RADA16) Hydrogel - Skull Base Neoplasms, Cerebrospinal Fluid Leakage | Not applicable | Recruiting | Indiana University | 30 | 2023-10-09 | 2026-08-27 |
| Chemosensory Dysfunction and Recovery in Endoscopic Endonasal Skull Base Surgery Olfactory training, Placebo training - Anosmia, Skull Base Neoplasms | Not applicable | Completed | Johns Hopkins University | 41 | 2023-02-01 | 2026-02-18 |
| Utility of Indocyanine Green Fluorescence in Endoscopic Sinonasal and Skull Base Surgery Sinonasal Benign or Malignant Tumor Resection, Skull Base Surgery (Assessment of Nasoseptal Flap), Endoscopic Sinus Surgery - Chronic Sinusitis, Tumor of Nasal Sinus | Not applicable | Unknown | St. Paul's Sinus Centre | 40 | 2023-01-01 | 2022-11-14 |
| Prospective Study of Sinonasal and Skull-base Tumours Management Nasal Neoplasm, Nasal Neoplasm Benign | Recruiting | University Medical Centre Ljubljana | 120 | 2022-01-01 | 2026-04-29 | |
| The Role of 5-Aminolevulinic Acid Fluorescence-Guided Surgery in Head and Neck Cancers: a Pilot Trial 5-Aminolevulinic acid Hydrochloride - Neoplasm, Skull Base Neoplasm | Phase 2 | Terminated | Icahn School of Medicine at Mount Sinai | 7 | 2021-09-14 | 2025-07-28 |
| Auditory Nerve Test System During Vestibular Schwannoma Resection Auditory Nerve Test System - Vestibular Schwannoma, Acoustic Neuroma | Not applicable | Completed | Washington University School of Medicine | 10 | 2020-01-20 | 2024-04-25 |
| Evaluation of Acupuncture Effects for Complications After Surgery of Cerebellopontine Angle Tumor in Skull Base Acupuncture, Tumor, Brain | Unknown | Taipei Veterans General Hospital, Taiwan | 32 | 2019-11-20 | 2020-01-31 | |
| Observational Trial of the Impact of Radiation Dose in Children With Brain and Skull Base Tumors. Brain Tumor, Brain Cancer | Active not recruiting | Baptist Health South Florida | 60 | 2019-03-08 | 2026-07-14 | |
| Molecular and Cellular Characterization of Skull Base Tumors Observation - Skull Base Neoplasm, Cellular Pathology | Recruiting | University of Pittsburgh | 4000 | 2018-10-03 | 2026-09-25 | |
| Skull Base Reconstruction After Endonasal Cranio-endoscopic Resection Using Autologus Grafts Skull Base Neoplasms | Unknown | Assiut University | 50 | 2018-01-01 | 2018-02-28 | |
| Proposal for Intraoperative Administration of Intravenous Indocyanine Green to Evaluate Position of the Optic Canal, Position of the Internal Carotid Arteries, Tumor Vascularization, and Vessel Encasement in Endoscopic Endonasal Cranial Base Surgery near-infrared light nasal endoscope used with ICG - Skull Base Neoplasms, Skull Neoplasms | Not applicable | Completed | Ohio State University | 23 | 2017-11-06 | 2021-04-26 |
| Effects on the Awakening With Laryngeal Mask vs Endotracheal Tube in Endoscopic Endonasal Transsphenoidal Base Surgery endotracheal tube, Laryngeal mask - Skull Base Neoplasms | Not applicable | Completed | Fundacion Clinic per a la Recerca Biomédica | 45 | 2017-01-20 | 2020-05-29 |
| Improvement of Outcomes in Draf III/Endoscopic Modified Lothrop Procedure Porcine Intestinal submucosal xenograft - Chronic Sinusitis, Frontal Sinusitis | Not applicable | Withdrawn | University of California, Los Angeles | 2016-11-01 | 2020-10-30 | |
| ICG Use in Angiography for Nasoseptal Flap Harvest indocyanine green - Skull Base Neoplasms | Not applicable | Completed | Ohio State University | 5 | 2015-03-01 | 2017-04-17 |
| In-Room PET in Proton Radiation Therapy PET scan - Brain Tumor, Head and Neck Tumor | Not applicable | Completed | Massachusetts General Hospital | 59 | 2010-10-01 | 2020-08-18 |
| Fluorescence Guided Resection of Brain Tumors 5-aminolevulinic acid - Brain Tumors | Phase 1 | Completed | David W. Roberts | 105 | 2007-05-01 | 2019-06-14 |
Brain Neoplasms (4) · Head and Neck Neoplasms (2) · Neoplasms (2) · Neuroma, Acoustic (2) · Anosmia (1) · Bone Diseases (1) · Bone Neoplasms (1) · Cerebrospinal Fluid Leak (1) · Frontal Sinusitis (1) · Glioma (1) · Hearing Loss, Sensorineural (1) · Hypertrophy (1) · Meningioma (1) · Musculoskeletal Diseases (1)
Neoplasms by Site (20) · Bone Diseases (19) · Bone Neoplasms (19) · Musculoskeletal Diseases (19) · Skull Neoplasms (19) · Neoplasms (18) · Nervous System Diseases (8) · Nervous System Neoplasms (5) · Otorhinolaryngologic Diseases (5) · Brain Diseases (4) · Central Nervous System Diseases (4) · Central Nervous System Neoplasms (4) · Otorhinolaryngologic Neoplasms (4) · Pathological Conditions, Signs and Symptoms (4) · Cranial Nerve Diseases (3)
Aminolevulinic Acid (2) · Indocyanine Green (2) · Laryngeal Masks (1) · Magnetic Resonance Spectroscopy (1) · Observation (1) · Olfactory Training (1)
Assiut University (2) · Ohio State University (2) · University of California, San Francisco (2) · Baptist Health South Florida (1) · Beijing Tiantan Hospital (1) · David W. Roberts (1) · Fundacion Clinic per a la Recerca Biomédica (1) · Icahn School of Medicine at Mount Sinai (1) · Indiana University (1) · Johns Hopkins University (1) · Massachusetts General Hospital (1) · St. Paul's Sinus Centre (1) · Taipei Veterans General Hospital, Taiwan (1) · University Medical Centre Ljubljana (1) · University of California, Los Angeles (1)
United States (13) · Egypt (2) · China (1) · Slovenia (1) · Spain (1) · Taiwan (1)
Daniel Prevedello, MD (2) · Ezequiel Goldschmidt, MD, PhD (2) · Alfred-Marc Iloreta, MD (1) · Cameron C Wick, MD (1) · David W Roberts, MD (1) · Domen Vozel, MD, PhD (1) · Helen A. Shih, MD (1) · Jeffrey D Suh, MD (1) · Keith Paulsen, PhD (1) · Matthew D Hall, MD (1) · Nicholas Rowan, MD (1) · Paola Hurtado, MD (1) · Paul Gardner, MD (1) · Ta-Peng Wu, MD/Master (1)
PMID 10449559, PMID 12943357, PMID 15519876, PMID 17562049, PMID 18769654, PMID 19650013, PMID 20592851, PMID 20592852, PMID 20851113, PMID 22858054, PMID 23573135, PMID 24904885, PMID 25745609, PMID 28811848, PMID 30666464, PMID 31083225, PMID 31511780, PMID 41560283
R01NS052274 (1)