26 completed, 12 unknown, 6 not yet recruiting, 5 recruiting. 27 Not applicable, 6 Phase 2, 4 Phase 1, 1 Early Phase 1, 1 Phase 3.
Follow Skull Neoplasms: new trials by email Literature Review of Skull Neoplasms trials Research Report on Skull Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ficerafusp Alfa, Pembrolizumab, and Stereotactic Body Radiotherapy (SBRT) for Head and Neck Squamous Cell Carcinoma (HNSCC) Hypofractionated Stereotactic Body Radiotherapy (SBRT), Pembrolizumab, Ficerafusp alfa - Head and Neck Squamous Cell Carcinoma, HPV-Negative Squamous Cell Carcinoma | Phase 1 / Phase 2 | Not yet recruiting | Washington University School of Medicine | 45 | 2026-09-30 | 2026-08-13 |
| Surgical Outcomes of Extended Endoscopic Endonasal Approach for Skull Base Lesions. Endoscopic Endonasal Approach for Skull Base Lesions. - Skull Base Neoplasms | Not applicable | Not yet recruiting | Assiut University | 30 | 2026-09-01 | 2026-08-26 |
| Functional and Aesthetic Comparison of Surgical Nasal Reconstruction Versus Nasal Prosthesis (Epithesis) After Total or Subtotal Nasal Amputation SCHNOS score - Nose Cancer, Rhinectomy | Not yet recruiting | Hôpital NOVO | 20 | 2026-07-01 | 2026-07-01 | |
| Assessment of Accuracy and Aesthetics Following Automated Mandibular Defect Reconstruction Using AI patient specific reconstruction plates - Mandibular Tumor | Not applicable | Not yet recruiting | Cairo University | 4 | 2025-05-01 | 2025-04-25 |
| Somesthesia in Cancer Patients: Variability and Influence on Eating Experience Salivary test, Food tasting, Questionnaires - Digestive Cancers, Breast Cancer | Not yet recruiting | Hospices Civils de Lyon | 96 | 2025-03-13 | 2025-02-06 | |
| Postoperative Complications Following Skull Base Tumor Resection Pulmonary ultrasound examination - Skull Base Tumor, Postoperative Complications | Recruiting | Beijing Tiantan Hospital | 122 | 2024-09-10 | 2025-02-14 | |
| Optic Nerve Stimulation To Prevent Visual Deficits After Endoscopic Cranial Approaches Optic Nerve Stimulation - Optic Nerve Injuries, Sellar Tumor | Not applicable | Not yet recruiting | University of California, San Francisco | 20 | 2024-08-01 | 2024-07-12 |
| Evaluating the Usefulness of 18F-AlF-FAPI PET/ CT in Orbital Neoplasms 18F-AlF-FAPI PET/CT, 18F-FDG PET/CT - Orbital Neoplasms | Not applicable | Recruiting | Peking University Third Hospital | 50 | 2024-07-16 | 2025-01-24 |
| ICG Angiogram as a Predictor of Postoperative Visual Function After EEA Surgery Indocyanine Green - Indocyanine Green, Skull Base Neoplasms | Unknown | University of California, San Francisco | 40 | 2024-07-01 | 2024-07-22 | |
| Role of Novel RADA16 Hydrogel in Endoscopic Skull Base Surgery Non-Absorbable Packing (Silastic Splint), PuraGel (RADA16) Hydrogel - Skull Base Neoplasms, Cerebrospinal Fluid Leakage | Not applicable | Recruiting | Indiana University | 30 | 2023-10-09 | 2026-08-27 |
| Bone Lid Technique Versus Standard Technique for Treatment of Mandibular Lesions bone lid technique, standard technique - Mandible Cyst, Mandible Tumor | Not applicable | Completed | Tanta University | 24 | 2023-06-20 | 2024-01-11 |
| A Clinical Study on Oncolytic Virus Injection (R130 OV) for the Treatment of Relapsed/Refractory Head and Neck Cancer Recombinant oncolytic herpes simplex virus type 1 (R130) - Head and Neck Cancer, Esophageal Cancer | Early Phase 1 | Unknown | Shanghai Yunying Medical Technology | 9 | 2023-03-27 | 2023-04-26 |
| Chemosensory Dysfunction and Recovery in Endoscopic Endonasal Skull Base Surgery Olfactory training, Placebo training - Anosmia, Skull Base Neoplasms | Not applicable | Completed | Johns Hopkins University | 41 | 2023-02-01 | 2026-02-18 |
| Perioperative Supplementation With Immunonutrition and Its Impact on Surgical Outcome and Pain in Oral Cavity or Mandibular Tumours Standard feeding, Omega 3 and dipeptiven - Immunonutrition, Surgical Outcome | Not applicable | Completed | Cairo University | 176 | 2023-02-01 | 2024-04-02 |
| Descriptive Study of a Cohort of Orbital Solitary Fibrous Tumors Phone call - Orbital Tumor | Completed | Fondation Ophtalmologique Adolphe de Rothschild | 10 | 2023-01-26 | 2023-10-23 | |
| Utility of Indocyanine Green Fluorescence in Endoscopic Sinonasal and Skull Base Surgery Sinonasal Benign or Malignant Tumor Resection, Skull Base Surgery (Assessment of Nasoseptal Flap), Endoscopic Sinus Surgery - Chronic Sinusitis, Tumor of Nasal Sinus | Not applicable | Unknown | St. Paul's Sinus Centre | 40 | 2023-01-01 | 2022-11-14 |
| Mandibular Reconstruction Bone Plate Mandibular marginal resection and reconstruction, mandibular osteosynthesis a 2.3mm reconstruction bone plate - Mandible Tumor | Not applicable | Enrolling by invitation | Tanta University | 16 | 2022-12-22 | 2025-04-10 |
| Artificial Intelligence-assisted Screening of Malignant Pigmented Tumors on the Ocular Surface screening system for ocular surface malignant tumors - Orbital Neoplasms, Conjunctival Neoplasms | Completed | Sun Yat-sen University | 535 | 2022-12-05 | 2024-08-05 | |
| Phase 2 Study of Bintrafusp Alfa in Recurrent/Metastatic Olfactory Neuroblastoma (BARON). Bintrafusp alfa/M7824, Ibuprofen, PET scan - Olfactory Neuroblastoma, Esthesioneuroblastoma | Phase 2 | Completed | National Cancer Institute (NCI) | 11 | 2022-06-21 | 2025-08-08 |
| Application of CAD-CAM Technology in Orbital Bone Reconstruction orbital bone reconstruction with patient specific titanium implant, orbital bone reconstruction with preformed titanium plate preoperatively bended on stereolithographic model - Orbital Bone Fracture, Maxillary Cyst | Not applicable | Unknown | Hatem Adel Aboelhassan | 34 | 2022-06-01 | 2022-06-30 |
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Skull Base Neoplasms (20) · Nose Neoplasms (10) · Mandibular Neoplasms (9) · Orbital Neoplasms (9) · Head and Neck Neoplasms (7) · Maxillary Neoplasms (6) · Brain Neoplasms (4) · Jaw Neoplasms (4) · Neoplasms (4) · Laryngeal Neoplasms (3) · Mouth Neoplasms (3) · Pharyngeal Neoplasms (3) · Tongue Neoplasms (3) · Breast Neoplasms (2) · Dentofacial Deformities (2)
Bone Diseases (54) · Bone Neoplasms (54) · Musculoskeletal Diseases (54) · Neoplasms by Site (54) · Neoplasms (51) · Stomatognathic Diseases (21) · Jaw Diseases (17) · Otorhinolaryngologic Diseases (16) · Nervous System Diseases (15) · Jaw Neoplasms (14) · Otorhinolaryngologic Neoplasms (13) · Respiratory Tract Diseases (13) · Nose Diseases (12) · Respiratory Tract Neoplasms (12)
Aminolevulinic Acid (2) · Indocyanine Green (2) · Radiotherapy (2) · pembrolizumab (2) · Carboplatin (1) · Cetuximab (1) · Deglutition (1) · Docosahexaenoic Acids (1) · Echocardiography, Doppler (1) · Electrocardiography (1) · Fluorouracil (1) · Hydroxyurea (1) · Ibuprofen (1) · Laryngeal Masks (1) · Machine Learning Algorithms (1)
Cairo University (4) · Fondation Ophtalmologique Adolphe de Rothschild (4) · The University of Hong Kong (3) · Assiut University (2) · Hospices Civils de Lyon (2) · Ohio State University (2) · Sun Yat-sen University (2) · Tanta University (2) · University of California, San Francisco (2) · Washington University School of Medicine (2) · Atara Biotherapeutics (1) · Baptist Health South Florida (1) · Beijing Tiantan Hospital (1) · Beijing Tongren Hospital (1) · David W. Roberts (1)
United States (21) · Egypt (9) · France (7) · China (5) · Hong Kong (3) · Taiwan (2) · Brazil (1) · India (1) · Malaysia (1) · Singapore (1) · Slovenia (1) · Spain (1) · Switzerland (1) · Thailand (1) · United Kingdom (1)
Daniel Prevedello, MD (2) · Ezequiel Goldschmidt, MD, PhD (2) · A Goodson, MBBS (1) · Aditi Mehta, DO (1) · Alfred-Marc Iloreta, MD (1) · Bhishamjit Chera, MD (1) · Brian R Gastman, MD (1) · Cameron C Wick, MD (1) · Charalampos Floudas, M.D. (1) · David W Roberts, MD (1) · Domen Vozel, MD, PhD (1) · Gamal Ashour (1) · Haitao Wu, Phd (1)
PMID 38597586, PMID 10449559, PMID 12943357, PMID 15519876, PMID 17562049, PMID 18769654, PMID 19650013, PMID 20592851, PMID 20592852, PMID 20830768, PMID 20851113, PMID 22858054, PMID 23573135, PMID 24904885, PMID 25745609, PMID 28811848, PMID 29496055, PMID 30561067, PMID 30666464, PMID 31083225, PMID 31230767, PMID 31501989, PMID 31511780, PMID 31892445, PMID 32572853, PMID 38453407, PMID 39095818, PMID 39241963, PMID 39500789, PMID 41560283, PMID 42240998, PMID 42307670
R01NS052274 (1)