26 completed, 2 unknown, 1 not yet recruiting, 1 recruiting. 18 Not applicable, 3 Phase 2, 3 Phase 3, 2 Phase 1, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 18 | Completed 14, Unknown 2, Not yet recruiting 1, Withdrawn 1 |
| Phase 2 | 3 | Completed 3 |
| Phase 3 | 3 | Completed 3 |
| Phase 1 | 2 | Completed 2 |
| Phase 4 | 2 | Completed 2 |
Follow Seasonal Affective Disorder: new trials by email Literature Review of Seasonal Affective Disorder trials Research Report on Seasonal Affective Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Virtual Reality Digital Therapeutics for Seasonal Affective Disorder Virtual Reality (VR) Intervention, Light Box (LB) intervention - Seasonal Affective Disorder (SAD) | Not applicable | Not yet recruiting | Anglia Ruskin University | 60 | 2025-10-27 | 2025-09-08 |
| Cohort of Patients Suffering From Major Depressive Episode With Evaluation of Sleep, Circadian Rhythms and Psychiatric Disorders Major Depressive Episode | Recruiting | Assistance Publique - Hôpitaux de Paris | 1000 | 2023-02-01 | 2026-08-12 | |
| Health Consequences of Wintering in the French Southern and Antarctic Territories Questionary - Environmental Exposure, Winter Depression | Not applicable | Completed | Centre Hospitalier Universitaire de la Réunion | 232 | 2021-04-20 | 2023-09-21 |
| Infrared Photomodulation Therapy for Seasonal Affective Disorder Joovv Mini - Seasonal Affective Disorder | Not applicable | Withdrawn | ProofPilot | 2020-02-27 | 2026-09-17 | |
| Vitamin D Supplementation and Effects on Mood in Emergency Medicine Residents Vitamin D, No Vitamin D - Seasonal Mood Disorder | Not applicable | Completed | Corewell Health South | 27 | 2018-10-01 | 2024-11-29 |
| Optimizing Long-Term Outcomes for Winter Depression With CBT-SAD and Light Therapy Cognitive-Behavioral Therapy (CBT-SAD), Light Therapy - Seasonal Affective Disorder | Not applicable | Completed | University of Vermont | 141 | 2018-09-01 | 2025-06-03 |
| Seasonal Affective Disorder and Visual Impairment light therapy - Seasonal Affective Disorder, Visual Impairment | Not applicable | Completed | Psychiatric Centre Rigshospitalet | 18 | 2017-12-01 | 2020-09-16 |
| Investigation of Seasonal Variations of Brain Structure and Connectivity in SAD Bright Light Therapy - Seasonal Affective Disorder, Major Depressive Disorder | Not applicable | Completed | Sunnybrook Health Sciences Centre | 23 | 2017-11-01 | 2021-03-16 |
| Influence of Light Exposure on Cerebral MAO-A in Seasonal Affective Disorder and Healthy Controls Measured by PET Light Therapy, Placebo Light - Seasonal Affective Disorder | Not applicable | Completed | Medical University of Vienna | 99 | 2013-11-01 | 2018-05-09 |
| Transcranial Bright Light Therapy in Seasonal Affective Disorder (SAD) Transcranial bright light therapy, Transcranial placebo treatment - Seasonal Affective Disorder (SAD) | Not applicable | Completed | University of Oulu | 60 | 2013-01-01 | 2013-06-28 |
| 30-Minute Light Exposure for the Treatment of Seasonal Affective Disorder goLITE, Control - Seasonal Affective Disorder | Not applicable | Completed | Philips Respironics | 35 | 2012-01-06 | 2019-01-30 |
| The Role of Vitamin D Supplementation on Well Being and Symptoms of Depression During the Winter Season in Health Service Staff Vitamin D3, Placebo - Seasonal Affective Disorder, Vitamin D3 | Phase 4 | Completed | Connie Thuree Nielsen, consultant, MD, ph.d | 50 | 2011-10-01 | 2012-03-29 |
| Bright Light Therapy in Seasonal Affective Disorder (SAD) Transcranial Brain-Targeted Bright Light Treatment - Seasonal Affective Disorder | Not applicable | Completed | University of Oulu | 90 | 2010-11-01 | 2011-06-01 |
| Bright Light Therapy in Seasonal Affective Disorder (SAD) Bright light therapy, Inactive "placebo-light" - Seasonal Affective Disorder | Not applicable | Unknown | University of Oulu | 60 | 2009-10-01 | 2009-12-11 |
| A Trial of Negative Ion Generation Versus Light-Emitting Diode Phototherapy for Seasonal Affective Disorder (SAD) Negative Ion Generator, Light-emitting Photodiode light treatment device - Seasonal Affective Disorder | Phase 2 / Phase 3 | Completed | Yale University | 106 | 2008-12-01 | 2013-03-06 |
| Study of Genes in Relation to Seasonal Affective Disorder and Major Depressive Disorder Seasonal Affective Disorder | Completed | University of Pittsburgh | 30 | 2008-10-01 | 2016-01-07 | |
| Low Intensity 'Blue Light' Treatment of Seasonal Affective Disorder Blue enriched light with a low intensity, standard light treatment - Seasonal Affective Disorder | Not applicable | Completed | University Medical Center Groningen | 22 | 2008-10-01 | 2011-08-10 |
| Cognitive-behavioral Therapy vs. Light Therapy for Preventing SAD Recurrence Cognitive-Behavioral Therapy (CBT), Light Therapy (LT) - Seasonal Affective Disorder (SAD), Winter Depression | Not applicable | Completed | University of Vermont | 177 | 2008-07-01 | 2023-05-09 |
| Predicting Effectiveness of Light Treatment for Winter Seasonal Affective Disorder Bright light, Red light placebo - Depression | Completed | University of Maryland, Baltimore | 41 | 2007-11-01 | 2019-11-21 | |
| Research Study of Treatment for Winter Depression With Different Colors of Light Blue Light Box 467 nm, Red Light Box 657 nm - Seasonal Affective Disorder | Phase 2 | Completed | Thomas Jefferson University | 9 | 2006-11-01 | 2016-03-28 |
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Depression (6) · Depressive Disorder, Major (6) · Recurrence (2) · Bipolar Disorder (1) · Depressive Disorder (1) · Disease (1) · Endocrine System Diseases (1) · Mental Disorders (1) · Mood Disorders (1) · Psychological Well-Being (1) · Sleep Wake Disorders (1) · Vision Disorders (1)
Depressive Disorder (30) · Mental Disorders (30) · Mood Disorders (30) · Behavior (7) · Behavioral Symptoms (6) · Pathological Conditions, Signs and Symptoms (5) · Pathologic Processes (3) · Disease Attributes (2) · Nervous System Diseases (2) · Neurologic Manifestations (2) · Signs and Symptoms (2) · Bipolar and Related Disorders (1) · Eye Diseases (1) · Personal Satisfaction (1) · Sensation Disorders (1)
Phototherapy (5) · Cognitive Behavioral Therapy (3) · Ultraviolet Therapy (2) · Cholecalciferol (1) · Exercise (1) · Methods (1) · Pharmaceutical Preparations (1) · Propranolol (1) · Sagittal Abdominal Diameter (1) · Vitamin D (1) · ramelteon (1)
GlaxoSmithKline (3) · University of Oulu (3) · National Institute of Mental Health (NIMH) (2) · University Medical Center Groningen (2) · University of Vermont (2) · Yale University (2) · Anglia Ruskin University (1) · Assistance Publique - Hôpitaux de Paris (1) · Brigham and Women's Hospital (1) · Centre Hospitalier Universitaire de la Réunion (1) · Connie Thuree Nielsen, consultant, MD, ph.d (1) · Corewell Health South (1) · Henry M. Jackson Foundation for the Advancement of Military Medicine (1) · Lehigh Valley Hospital (1) · Medical University of Vienna (1)
United States (18) · Canada (5) · Finland (3) · Netherlands (3) · Denmark (2) · Austria (1) · France (1) · Reunion (1)
Kelly J Rohan, Ph.D. (2) · Alfredo Rivera, MD (1) · Carol Glod, PhD (1) · Edward R. Norris, MD (1) · George C Brainard, Ph.D. (1) · Jane Scott, PhD (1) · Janis Anderson, PhD (1) · Janis L Anderson, Ph.D (1) · Kathryn A Roecklein, PhD (1) · Kelly J. Rohan, PhD (1) · Michael Terman (1)
PMID 17683643, PMID 19207131, PMID 21911257, PMID 23514124, PMID 25125215, PMID 25330838, PMID 25859764, PMID 26539881, PMID 32700956, PMID 35550645, PMID 36573644, PMID 36858765, PMID 37322010, PMID 37330257, PMID 38160889, PMID 40114401, PMID 41113438
R01MH042931 (1), R01MH078982 (1), R03MH065946 (1), R34MH073797 (1)