12 completed, 6 unknown, 1 not yet recruiting, 1 recruiting. 10 Not applicable, 5 Phase 4, 3 Phase 3, 2 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 5, Unknown 4, Not yet recruiting 1 |
| Phase 4 | 5 | Completed 4, Unknown 1 |
| Phase 3 | 3 | Completed 2, Unknown 1 |
| Early Phase 1 | 2 | Completed 1, Recruiting 1 |
Follow Ropivacaine: new trials by email Literature Review of Ropivacaine trials Research Report on Ropivacaine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Liposomal Bupivacaine Versus Ropivacaine With Perineural Dexamethasone or Dexmedetomidine as Adjuncts for Adductor Canal Block Combined With IPACK Block in Total Knee Arthroplasty Liposomal bupivacaine (LB), Ropivacaine with Perineural Dexamethasone, Ropivacaine with Perineural Dexmedetomidine - Total Knee Anthroplasty, Nerve Block | Not applicable | Completed | Huazhong University of Science and Technology | 90 | 2026-04-09 | 2026-10-06 |
| Dexmedetomidine-esketamine-ropivacaine Versus Sufentanil-ropivacaine for Epidural Labor Analgesia sufentanil-ropivacaine combination, dexmedetomidine-esketamine-ropivacaine combination 1, dexmedetomidine-esketamine-ropivacaine combination 2 - Epidural Analgesia, Labor Pain | Phase 4 | Completed | Peking University First Hospital | 300 | 2025-09-05 | 2026-04-13 |
| Effects of Ropivacaine Concentrations on Prolonged Labor Analgesia High-concentration Ropivacaine, Low concentration ropivacaine group - Labor Analgesia, Prolonged | Not applicable | Not yet recruiting | Chengdu Jinjiang Maternity and Child Health Hospital | 100 | 2025-06-14 | 2025-06-06 |
| Testing the Feasibility of Using Ropivacaine in Spinal Anesthesia for Patients With Lower Back Surgery Spinal anesthesia for lumbar surgery: ropivacaine, Spinal anesthesia for lumbar surgery: bupivacaine, General anesthesia for lumbar surgery - Anesthesia, Spinal, Neurosurgery | Early Phase 1 | Recruiting | Fraser Health | 45 | 2024-08-27 | 2024-10-08 |
| Ultrasound-guided Infraclavicular Block With Lidocaine or Ropivacaine for Closed Reduction of Distal Radius Fractures Ropivacaine 0.2% Injectable Solution, Lidocaine epinephrine, Ropivacaine 0.5% Injectable Solution - Distal Radius Fractures, Lidocaine | Phase 3 | Completed | Nordsjaellands Hospital | 67 | 2024-04-23 | 2025-06-26 |
| Analgesic Efficacy of Peritonsillar Ropivacaine Infiltration After Tonsillectomy in Children Peritonsillar infiltration with ropivacaine, Peritonsillar infiltration with normal saline, Normal Saline - Tonsillectomy, Ropivacaine | Not applicable | Completed | University Hospital, Mahdia | 60 | 2024-03-01 | 2026-09-17 |
| Effect of Intraperitoneal Ropivacaine on Visceral Pain After Laparoscopic Gastrectomy 0.5% Ropivacaine, Saline - Laparoscopic Gastrectomy, Ropivacaine | Not applicable | Unknown | SanQing Jin | 72 | 2023-11-25 | 2023-11-28 |
| Liposomal Bupivacaine vs Ropivacaine for TAPBs Liposomal Bupivacaine, Ropivacaine - Abdominal Tumor, Postoperative Analgesia | Phase 3 | Unknown | Sun Yat-sen University | 74 | 2023-11-01 | 2024-05-28 |
| Effect of Subperiosteal Ropivacaine After Third Molar Extraction Ropivacaine 0.75%, Saline (0.9% NaCl) - Wisdom Tooth Removal, Dental Anesthesia | Phase 4 | Completed | University of Zagreb | 30 | 2023-10-02 | 2026-09-28 |
| Comparative Study on Postoperative Analgesia With Transversus Abdominis Plane Block to Local Anesthetic Infiltration With Ropivacaine in Laparoscopic Abdominal Surgery Ropivacaine in Transversus abdominis plane, Ropivacaine in Local infiltration at port site - Analgesia, Ropivacaine | Not applicable | Completed | National Academy of Medical Sciences, Nepal | 100 | 2022-03-12 | 2023-08-28 |
| Dexamethasone and Dexmedetomidine as Adjuvants to Ropivacaine in Ultrasound-guided Multilevel Thoracic Paravertebral Block for Lobectomy: A Prospective, Randomized, Triple-blind Study dexamethasone; dexmedetomidine; ropivacaine - Dexamethasone, Dexmedetomidine | Phase 4 | Unknown | Gansu Provincial Hospital | 90 | 2021-03-20 | 2021-02-21 |
| The Optimal Dosage of Ropivacaine for Arthroscopic Knee Surgery ropivacaine - Arthroscopic Knee Surgery, Ropivacaine | Early Phase 1 | Completed | Yanchao Yang | 115 | 2021-03-01 | 2023-08-15 |
| EFFECT - EFFectiveness of ESPB (Erector Spinae Plane Block) in Laparoscopic Cοlectomies Trial Ropivacaine injection - Pain, Postoperative, Acute Pain | Not applicable | Unknown | Democritus University of Thrace | 40 | 2021-01-01 | 2021-05-10 |
| Caudal Ropivacaine With or Without Dexmedetomidine for Post Operative Analgesia ropivacaine with dexmedetomidine, Ropivacaine with placebo - Ropivacaine, Infraumbilical Surgery | Not applicable | Completed | National Academy of Medical Sciences, Nepal | 62 | 2020-06-16 | 2023-08-07 |
| Minimal Effective Concentration (EC90) of Ropivacaine Intravenous dexamethasone, Intravenous saline, Perineural ropivacaine - Anesthesia, Conduction, Ropivacaine | Phase 3 | Completed | Centre Hospitalier Universitaire de Besancon | 146 | 2018-10-05 | 2020-12-21 |
| Ropivacaine vs Lidocaine in the Endotracheal Tube Cuff on Post-Operative Sore Throat Ropivacaine 0.5% Injectable Solution, Lidocaine 2% Preservative-Free Injectable Solution, Air - Pharyngitis, Lidocaine | Not applicable | Completed | University of Saskatchewan | 63 | 2018-08-01 | 2019-01-17 |
| Labour Epidural Top-up With Warmed Ropivacaine warming of ropivacaine for BT, Ropivicaine - Epidural Top-up, Labour | Not applicable | Unknown | Guy's and St Thomas' NHS Foundation Trust | 90 | 2016-07-01 | 2018-02-22 |
| Effect of Nervus Cutaneous Femoris Lateralis-Blockade on Moderate Pain Responders After Total Hip Arthroplasty Ropivacaine, Saline - Pain, Postoperative, Ropivacaine | Phase 4 | Completed | Daniel Hägi-Pedersen | 60 | 2015-01-01 | 2015-09-25 |
| Ropivacaine Use Intraincisionally Versus Intraperitoneally for Post-Laparoscopic Cholecystectomy Pain 0.2% ropivacaine - Ropivacaine, Laparoscopic Cholecystectomy | Phase 4 | Completed | Jawaharlal Nehru Medical College | 353 | 2014-04-01 | 2017-08-30 |
| Effect of 0.5% vs 0.375% Ropivacaine on Autonomous Nervous System Interscalene nerve block - Shoulder Surgery, Interscalene Nerve Block | Not applicable | Unknown | Larissa University Hospital | 100 | 2014-03-01 | 2014-04-29 |
Agnosia (4) · Pain (2) · Pain, Postoperative (2) · Abdominal Neoplasms (1) · Acute Pain (1) · Colles' Fracture (1) · Colorectal Neoplasms (1) · Fracture Dislocation (1) · Labor Pain (1) · Pharyngitis (1) · Postoperative Complications (1) · Shoulder Pain (1) · Visceral Pain (1) · Wrist Fractures (1)
Neurologic Manifestations (8) · Pathological Conditions, Signs and Symptoms (8) · Signs and Symptoms (8) · Nervous System Diseases (4) · Neurobehavioral Manifestations (4) · Perceptual Disorders (4) · Pain (3) · Joint Diseases (2) · Musculoskeletal Diseases (2) · Neoplasms (2) · Neoplasms by Site (2) · Pathologic Processes (2) · Arm Injuries (1) · Arthralgia (1) · Colonic Diseases (1)
Ropivacaine (14) · Sodium Chloride (3) · Dexmedetomidine (2) · Lidocaine (2) · Air (1) · Anesthesia, General (1) · Anesthesia, Spinal (1) · Bupivacaine (1) · Dexamethasone (1) · Intubation, Intratracheal (1) · Saline Solution (1)
National Academy of Medical Sciences, Nepal (2) · Centre Hospitalier Universitaire de Besancon (1) · Chengdu Jinjiang Maternity and Child Health Hospital (1) · Daniel Hägi-Pedersen (1) · Democritus University of Thrace (1) · Fraser Health (1) · Gansu Provincial Hospital (1) · Guy's and St Thomas' NHS Foundation Trust (1) · Huazhong University of Science and Technology (1) · Jawaharlal Nehru Medical College (1) · Larissa University Hospital (1) · Nordsjaellands Hospital (1) · Peking University First Hospital (1) · SanQing Jin (1) · Sun Yat-sen University (1)
China (6) · Canada (2) · Denmark (2) · Greece (2) · Nepal (2) · Croatia (1) · France (1) · Tunisia (1) · United Kingdom (1)
Alan Tung, MD (1) · Aristeidis Zibis, Medicine (1) · Bidur K Baral, MBBS,MD (1) · Brihaspati K C, MD (1) · Davor Brajdic, DMD, PhD (1) · Dong-Xin Wang, MD,PhD (1) · George Basdekis, Medicine (1) · Jingdun Xie (1) · Jonathan Gamble, MD, FRCPC (1) · Kate Cheesman, MBBS (1) · Kaushal D Singh, MS Surgery (1) · Kaushal Tamang, MBBS,MD (1)
PMID 20410515, PMID 26832926, PMID 33078536, PMID 33533982, PMID 35157756, PMID 35281318, PMID 35443838, PMID 37302963, PMID 39488417, PMID 39753406, PMID 39773190, PMID 39806707, PMID 42104772
2014 (1)