16 unknown. 16 Phase 2, 4 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 16 | Unknown 16 |
| Phase 3 | 4 | Unknown 4 |
Follow Respiratory Insufficiency: new trials by email Literature Review of Respiratory Insufficiency trials Research Report on Respiratory Insufficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MRG-001 as an Immunoregulatory and Regenerative Therapy for ARDS Patients MRG-001 (Low-dose), MRG-001 (High-dose), Placebo - Acute Respiratory Distress Syndrome, Respiratory Failure | Phase 2 | Unknown | MedRegen LLC | 60 | 2024-12-01 | 2024-08-23 |
| Biological Effects of Quercetin in COPD Phase II Quercetin 1000 mg, Quercetin 500 MG, Placebo - Chronic Obstructive Pulmonary Disease, Emphysema | Phase 2 | Unknown | Temple University | 30 | 2023-11-01 | 2024-04-08 |
| Angiotensin-(1,7) Treatment in COVID-19: the ATCO Trial Angiotensin 1-7, Placebos - Coronavirus, Respiratory Failure | Phase 2 / Phase 3 | Unknown | Erasme University Hospital | 60 | 2021-12-30 | 2021-08-02 |
| High Flow Nasal Cannula Oxygen During Sedation for Video-assisted Thoracoscopic Surgery High flow nasal cannula, CONTROL - Chronic Obstructive Pulmonary Disease, Respiratory Failure | Phase 2 | Unknown | Alexandria University | 60 | 2020-08-01 | 2020-08-20 |
| Study to Assess Efficacy and Safety Relative to Standard of Care in Patients With COVID-19 Pneumonia Standard of Care (SOC) + ANG-3777, Standard Of Care (SOC) + Placebo - COVID-19, Pneumonia | Phase 2 | Unknown | Angion Biomedica Corp | 100 | 2020-07-31 | 2021-04-15 |
| Hemostasis in COVID-19: an Adaptive Clinical Trial acetylsalicylic acid, Unfractionated heparin nebulized - COVID-19 | Phase 2 | Unknown | University of Sao Paulo General Hospital | 379 | 2020-07-11 | 2021-06-09 |
| Airway Clearance Using Non-Invasive Oscillating Device NIOD Frequencer - Respiratory Insufficiency | Phase 2 / Phase 3 | Unknown | St. Justine's Hospital | 20 | 2020-06-01 | 2020-03-17 |
| Immunoregulatory Therapy for 2019-nCoV PD-1 blocking antibody+standard treatment, Thymosin+standard treatment, standard treatment - 2019 nCoV, PD-1 | Phase 2 | Unknown | Southeast University, China | 120 | 2020-02-10 | 2020-02-13 |
| Fluid Restriction Keeps Children Dry Restrictive fluid regimen, Liberal fluid regimen - Respiratory Infection, Fluid Overload | Phase 2 / Phase 3 | Unknown | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 34 | 2016-09-01 | 2016-12-12 |
| Non-invasive Measurements of Elastance and Resistance Invasive method, Non invasive method - Respiratory Insufficiency | Phase 2 | Unknown | University of Turin, Italy | 15 | 2012-02-01 | 2012-02-09 |
| Airway Pressure Release Ventilation (APRV) Versus AC/VC Conventional Ventilation Mechanical Ventilation - Respiratory Failure, Acute Lung Injury (ALI) | Phase 2 | Unknown | Intermountain Health Care, Inc. | 246 | 2011-10-01 | 2015-08-26 |
| Strategies to Optimize Positive End-expiratory Pressure (PEEP) in Patients With Acute Lung Injury PEEP titration - Acute Lung Injury, Acute Respiratory Distress Syndrome | Phase 2 | Unknown | University Hospital, Bonn | 40 | 2011-03-01 | 2011-03-30 |
| Comparison Between High-flow Nasal Cannula System and Non-invasive Ventilation in Acute Hypoxemic Respiratory Failure Non-invasive ventilation, High flow nasal cannula system - Acute Hypoxemic Respiratory Failure | Phase 2 / Phase 3 | Unknown | Asan Medical Center | 74 | 2010-07-01 | 2010-07-21 |
| Negative Pressure Ventilation Imapcts Weaning Ventilator In Medical Intensive Care Units (ICUs) negative pressure ventilator use - Respiratory Failure | Phase 2 | Unknown | Chang Gung Memorial Hospital | 120 | 2010-03-01 | 2010-07-02 |
| Comparison of High Dose and Low Dose Dexamethasone in Preventing Post-Extubation Airway Obstruction in Adults dexamethasone (Oradexon, Nederland) - Airway Obstruction | Phase 2 | Unknown | Mackay Memorial Hospital | 80 | 2007-04-01 | 2008-05-28 |
| Dexamethasone and the Prevention of Post-Extubation Airway Obstruction in Adults Dexamethasone - Airway Obstruction | Phase 2 | Unknown | Mackay Memorial Hospital | 70 | 2004-10-01 | 2007-03-26 |
Respiratory Distress Syndrome (4) · Acute Lung Injury (3) · Airway Obstruction (3) · COVID-19 (2) · Pulmonary Disease, Chronic Obstructive (2) · Coronavirus Infections (1) · Critical Illness (1) · Cytokine Release Syndrome (1) · Edema (1) · Emphysema (1) · Hemostatic Disorders (1) · Laryngeal Edema (1) · Parkinson Disease 4, Autosomal Dominant Lewy Body (1) · Pneumonia (1)
Respiration Disorders (16) · Respiratory Tract Diseases (15) · Lung Diseases (7) · Infections (4) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Coronaviridae Infections (3) · Disease Attributes (3) · Lung Injury (3) · Nidovirales Infections (3) · RNA Virus Infections (3) · Virus Diseases (3) · Chronic Disease (2) · Coronavirus Infections (2)
Dexamethasone (2) · Aspirin (1) · Noninvasive Ventilation (1) · Quercetin (1) · Respiration, Artificial (1) · Standard of Care (1) · angiotensin I (1-7) (1) · terevalefim (1)
Mackay Memorial Hospital (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Alexandria University (1) · Angion Biomedica Corp (1) · Asan Medical Center (1) · Chang Gung Memorial Hospital (1) · Erasme University Hospital (1) · Intermountain Health Care, Inc. (1) · MedRegen LLC (1) · Southeast University, China (1) · St. Justine's Hospital (1) · Temple University (1) · University Hospital, Bonn (1) · University of Sao Paulo General Hospital (1) · University of Turin, Italy (1)
Taiwan (3) · Brazil (2) · United States (2) · Egypt (1) · Germany (1) · Netherlands (1) · South Korea (1)
Chao-Hsien Lee, MD (2) · Atsushi Kawaguchi (1) · Chae-Man Lim, M.D. (1) · Christian Putensen, MD, Prof (1) · Eliotte Hirshberg, MD (1) · Filippo Annoni, MD (1) · Gordon R Bernard, MD (1) · John Neylan, MD (1) · Nathaniel Marchetti (1) · Rehab A. Abd Elaziz, Ass.Prof. (1) · Robson AS Santos, MD,PhD (1) · Thomas Muders, MD (1) · Vanderson Rocha (1)
PMID 15141377, PMID 16424722, PMID 16540947, PMID 17605780, PMID 20920189, PMID 20937093, PMID 22315264, PMID 22465313, PMID 23849147, PMID 23919993, PMID 24038922, PMID 29264361, PMID 29975735, PMID 31921715, PMID 31986264, PMID 32071149, PMID 32142651, PMID 32155444, PMID 32192578, PMID 32212240, PMID 32227760, PMID 32246450, PMID 32271988, PMID 32275452, PMID 32283155, PMID 32291094, PMID 32291954, PMID 32294295, PMID 32302438, PMID 32302462, PMID 32305740, PMID 32311448, PMID 32320517, PMID 32329246, PMID 32353746, PMID 32367170, PMID 32369666, PMID 32387623, PMID 32437596, PMID 32445064, PMID 32450344, PMID 32459672, PMID 32462179, PMID 32469410, PMID 33020101, PMID 37633275, PMID 8874303
R33AT009991 (1)