10 recruiting. 10 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Recruiting 10 |
| Phase 3 | 1 | Recruiting 1 |
Follow Respiratory Insufficiency: new trials by email Literature Review of Respiratory Insufficiency trials Research Report on Respiratory Insufficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT ALS) Non-invasive ventilation - Amyotrophic Lateral Sclerosis (ALS), Chronic Respiratory Failure | Phase 2 | Recruiting | University of Pennsylvania | 48 | 2026-06-11 | 2026-06-26 |
| A Clinical Trial to Evaluate agenT-797 Plus Standard of Care in Participants With Severe Pneumonia With Moderate to Severe Acute Hypoxemic Respiratory Failure agenT-797, Placebo, Standard of Care (SOC) - Pneumonia | Phase 2 | Recruiting | MiNK Therapeutics | 90 | 2026-05-26 | 2026-06-26 |
| Transpulmonary Assessment for Individualized Lung Optimization in Obese Patients Esophageal pressure-guided PEEP titration, Standard care PEEP management - Respiratory Failure | Phase 2 | Recruiting | University of Alberta | 30 | 2026-02-05 | 2026-04-13 |
| Interleukin-6 Guided Treatment With Dexamethasone or Tocilizumab in Patients Hospitalized With Acute Respiratory Symptoms - a Feasibility Study Tocilizumab (Actemra®), Dexamethasone - Acute Hypoxemic Respiratory Failure | Phase 2 | Recruiting | Lorenzo delSorbo | 60 | 2025-10-20 | 2026-10-09 |
| COMBO Endoscopy Oropharyngeal Airway in Sedated Endoscopic Retrograde Cholangiopancreatography for Patients The COMBO Endoscopy Oropharyngeal Airway - Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice | Phase 2 | Recruiting | Zhejiang University | 50 | 2025-06-12 | 2025-06-24 |
| Feasibility and Safety of Supraglottic Oxygen Delivery Via an Endotracheal Tube for Non-intubated ERCP Anesthesia: A Two-Stage Phase II Clinical Study Supraglottic Oxygen Delivery via an Endotracheal Tube - Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice | Phase 2 | Recruiting | Zhejiang University | 50 | 2025-06-12 | 2025-07-17 |
| A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma PF-07275315, Placebo - Asthma | Phase 2 | Recruiting | Pfizer | 252 | 2025-05-20 | 2026-10-13 |
| Nasal Obstruction With Oxymetazoline and Corticosteroids Oxymetazoline Nasal Spray, Budesonide nasal spray - Nasal Obstruction | Phase 2 | Recruiting | Washington University School of Medicine | 80 | 2024-10-15 | 2025-09-11 |
| Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS) Rhu-pGSN, normal saline - Acute Respiratory Distress Syndrome, Infections | Phase 2 | Recruiting | BioAegis Therapeutics Inc. | 600 | 2024-10-03 | 2026-10-20 |
| The Evaluation of the Effectiveness and Safety of Nalbuphine Hydrochloride Injection for Analgesia in ICU Patients: A Multicenter, Randomized, Single-blinded, Parallel, Two-step Trial Nalbuphine hydrochloride injection, Hydromorphone hydrochloride injection - Respiratory Insufficiency | Phase 2 / Phase 3 | Recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 204 | 2023-08-30 | 2025-01-21 |
Cholelithiasis (2) · Hypoxia (2) · Jaundice, Obstructive (2) · Pancreatitis (2) · Airway Obstruction (1) · Amyotrophic Lateral Sclerosis (1) · Asthma (1) · Dyspnea (1) · Infections (1) · Lung Diseases (1) · Nasal Obstruction (1) · Neuromuscular Diseases (1) · Obesity (1) · Pneumonia (1)
Respiration Disorders (10) · Respiratory Tract Diseases (9) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Signs and Symptoms, Respiratory (3) · Biliary Tract Diseases (2) · Digestive System Diseases (2) · Hyperbilirubinemia (2) · Jaundice (2) · Lung Diseases (2) · Nutritional and Metabolic Diseases (2) · Pancreatic Diseases (2) · Pathologic Processes (2) · Skin Manifestations (2)
Budesonide (1) · Continuous Positive Airway Pressure (1) · Dexamethasone (1) · Hydromorphone (1) · Nalbuphine (1) · Noninvasive Ventilation (1) · Oxymetazoline (1) · Saline Solution (1) · Standard of Care (1) · tocilizumab (1)
Zhejiang University (2) · BioAegis Therapeutics Inc. (1) · Lorenzo delSorbo (1) · MiNK Therapeutics (1) · Pfizer (1) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (1) · University of Alberta (1) · University of Pennsylvania (1) · Washington University School of Medicine (1)
United States (5) · China (4) · Canada (3) · Belgium (2) · Bulgaria (2) · Czechia (2) · Hungary (2) · Italy (2) · Spain (2) · United Kingdom (2) · Argentina (1) · France (1) · Germany (1) · Japan (1) · Netherlands (1)
Jason T Ackrivo, MD, MSCE (1) · Nyssa F Farrell, MD (1)