3 completed, 2 active not recruiting, 2 not yet recruiting. 7 Phase 2, 2 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 3, Active not recruiting 2, Not yet recruiting 2 |
| Phase 1 | 2 | Completed 2 |
| Phase 3 | 2 | Active not recruiting 1, Completed 1 |
Follow Respiratory Depression: new trials by email Literature Review of Respiratory Depression trials Research Report on Respiratory Depression
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oxytocin for Respiratory Compromise and Hypoventilation Induced by Drugs Intranasal Oxytocin 40 i.u., Intranasal Placebo Spray - Obesity & Overweight, Respiratory Depression | Phase 2 | Not yet recruiting | George Washington University | 100 | 2027-05-15 | 2026-10-29 |
| ENA-001 for Post Operative Respiratory Depression (PORD) ENA-001 - Respiratory Depression | Phase 2 | Not yet recruiting | Enalare Therapeutics Inc. | 200 | 2026-12-15 | 2026-02-27 |
| Pupillary Unrest as an Indicator of Central Opioid Effect in Subjects 40-60 Years of Age Remifentanil Hydrochloride, Pupillometry measurement - Opioid Toxicity, Pupillary Miosis | Phase 2 / Phase 3 | Completed | University of California, San Francisco | 10 | 2022-10-01 | 2025-05-02 |
| Vital Signs-Integrated Patient-Assisted Intravenous Opioid Analgesia for Post Surgical Pain VPIA pump, Morphine - Pain, Respiratory Depression | Phase 2 / Phase 3 | Active not recruiting | KK Women's and Children's Hospital | 40 | 2021-03-31 | 2026-08-07 |
| Vital-signs-integrated Patient-assisted Intravenous Opioid Analgesia VPIA analgesia, Morphine - Respiratory Depression | Phase 2 | Active not recruiting | KK Women's and Children's Hospital | 20 | 2016-12-29 | 2026-08-06 |
| Testing of the Apnea Prevention Device Verbal prompt, Skin Stimulus - Respiratory Depression, Elective Surgery | Phase 1 / Phase 2 | Completed | Oregon Health and Science University | 30 | 2009-03-01 | 2019-06-18 |
| Dexmedetomidine for the Control of Post-Operative Pain in Thoracotomy Patients Dexmedetomidine, Placebo (Normal Saline) - Post-operative Pain, Respiratory Depression | Phase 1 / Phase 2 | Completed | Baylor Research Institute | 38 | 2008-05-01 | 2016-02-08 |
Respiratory Insufficiency (7) · Pain, Postoperative (2) · Hypoventilation (1) · Miosis (1) · Obesity (1) · Obesity Hypoventilation Syndrome (1) · Overweight (1) · Pain (1)
Respiration Disorders (7) · Respiratory Tract Diseases (7) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Neurologic Manifestations (3) · Nervous System Diseases (2) · Pathologic Processes (2) · Postoperative Complications (2) · Apnea (1) · Body Weight (1) · Dyssomnias (1) · Eye Diseases (1) · Hypoventilation (1) · Nutrition Disorders (1) · Nutritional and Metabolic Diseases (1)
Morphine (2) · Dexmedetomidine (1) · Remifentanil (1) · Saline Solution (1)
KK Women's and Children's Hospital (2) · Baylor Research Institute (1) · Enalare Therapeutics Inc. (1) · George Washington University (1) · Oregon Health and Science University (1) · University of California, San Francisco (1)
United States (3) · Singapore (2)
Ban L Sng, FANZCA (1) · Ban Leong Sng, MBBS, MMED (1) · Michael Ramsay, MD, MD (1) · Rachel Eshima McKay, MD (1)
UG3DA062506-02 (1)