5 terminated, 4 completed, 1 withdrawn. 10 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 10 | Terminated 5, Completed 4, Withdrawn 1 |
Follow Renal Impairment: new trials by email Literature Review of Renal Impairment trials Research Report on Renal Impairment
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Gla-300 and IDeg-100 in Insulin-Naïve People With Type 2 Diabetes Mellitus and Renal Impairment Insulin glargine 300 U/mL, Insulin degludec 100 U/mL - Type 2 Diabetes Mellitus, Renal Impairment | Phase 4 | Terminated | Sanofi | 62 | 2022-12-05 | 2025-09-08 |
| Neurotoxic Adverse Effects of Morphine and Oxycodone for Pain in Terminal Patients With Diminished Renal Function Oxycodone, Morphine - Pain, Terminal Illness | Phase 4 | Terminated | Maastricht University Medical Center | 8 | 2018-06-04 | 2019-03-18 |
| Enoxaparin 20mg Versus 30mg Subcutaneously Once Daily in Elderly Patients With Impaired Renal Function Enoxaparin 20Mg/0.2mL Prefilled Syringe, Enoxaparin 60Mg/0.6Ml Inj Syringe 0.6Ml - Venous Thromboembolism, Renal Impairment | Phase 4 | Completed | Lebanese American University | 32 | 2015-10-24 | 2017-09-11 |
| An Open-label, Non-randomized, Parallel Group Study in Subjects With Mild, Moderate, Severe, or No Renal Impairment Deferiprone - Renal Impairment | Phase 4 | Completed | ApoPharma | 32 | 2013-01-01 | 2014-08-26 |
| Study of Daptomycin Safety and Efficacy for Complicated Skin and Skin Structure Infections (cSSSI) and Bacteremia in Renal Impairment Vancomycin, Daptomycin, Semi-Synthetic Penicillin - Complicated Skin and Skin Structure Infections, S. Aureus Bacteremia | Phase 4 | Terminated | Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 92 | 2010-04-19 | 2018-09-05 |
| A Post-Marketing Clinical Pharmacokinetics Study Of Gabapentin In Japanese Epileptic Subjects With Renal Impairment Gabapentin - Renal Impairment | Phase 4 | Terminated | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 1 | 2010-03-01 | 2021-02-03 |
| Effects of Contrast Media on Subjects With Stable Reduced Renal Function Undergoing Contrast-Enhanced Computed Tomography Ioversol 320 mgI/mL, Iodixanol 320 mgI/mL - Renal Impairment | Phase 4 | Terminated | Guerbet | 6 | 2009-01-01 | 2019-03-06 |
| Safety of Gadovist in Renally Impaired Patients Gadobutrol (Gadovist, BAY86-4875) - Fibrosis, Renal Impairment | Phase 4 | Completed | Bayer | 927 | 2008-12-01 | 2016-02-18 |
| Renal Effects of Three Iodinated Contrast Media (CM) in Patients at Risk Undergoing Coronary Angiography Iodixanol, Ioversol, Iopromide - Coronary Artery Disease (CAD), Renal Impairment | Phase 4 | Withdrawn | GE Healthcare | 2006-06-01 | 2019-04-29 | |
| Renal Effects of Two Iodinated Contrast Media in Patients at Risk Undergoing Coronary Angiography Iodixanol 320 mgI/mL - Coronary Artery Disease, Renal Impairment | Phase 4 | Completed | GE Healthcare | 408 | 2005-08-01 | 2007-10-31 |
Renal Insufficiency (10) · Coronary Artery Disease (2) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 2 (1) · Fibrosis (1) · Kidney Diseases (1) · Pain (1) · Venous Thromboembolism (1)
Female Urogenital Diseases (10) · Female Urogenital Diseases and Pregnancy Complications (10) · Male Urogenital Diseases (10) · Urogenital Diseases (10) · Urologic Diseases (10) · Kidney Diseases (9) · Cardiovascular Diseases (3) · Vascular Diseases (3) · Arterial Occlusive Diseases (2) · Arteriosclerosis (2) · Coronary Disease (2) · Endocrine System Diseases (2) · Glucose Metabolism Disorders (2) · Heart Diseases (2) · Metabolic Diseases (2)
iodixanol (2) · ioversol (2) · Cloxacillin (1) · Daptomycin (1) · Deferiprone (1) · Enoxaparin (1) · Gabapentin (1) · Insulin Glargine (1) · Isoflurophate (1) · Long Interspersed Nucleotide Elements (1) · Morphine (1) · Nafcillin (1) · Oxacillin (1) · Oxycodone (1) · Vancomycin (1)
GE Healthcare (2) · ApoPharma (1) · Bayer (1) · Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (1) · Guerbet (1) · Lebanese American University (1) · Maastricht University Medical Center (1) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (1) · Sanofi (1)
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Caroline Widlund, BSc RN (1) · Eddie Darton, MD (1) · Ellie Hershberger, Pharm.D. (1) · Fernando Tricta, MD (1) · Johnny Gibbs, Jr., B.S., CCRA (1) · Johnny Gibbs, Jr., CCRA (1) · Jos MG Schols, MD PhD (1) · Marc Pignot, PhD (1) · Mark JM Martens, MD (1) · Nibal R Chamoun, PharmD (1) · Sander MJ van Kuijk, PhD (1)
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