49 completed, 8 terminated, 5 withdrawn, 4 unknown. 23 Phase 4, 10 Phase 3, 9 Phase 2, 7 Phase 1, 6 Not applicable.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of the Efficacy and Safety of Magnetic Resonance Angiography (MRA) Using Gadopiclenol Compared to Gadoterate Meglumine in the Assessment of Steno-occlusive Disease in Adult Patients With Suspected Vascular Disease gadopiclenol, Gadoterate meglumine (Dotarem) - Steno-occlusive Disease | Phase 3 | Recruiting | Guerbet | 315 | 2026-07-28 | 2026-10-07 |
| High Relaxivity Contrast Agent for Cardiac MR in the Myocardial Scar Assessment Elucirem (Gadopiclenol) - Myocardial Fibrosis | Phase 4 | Recruiting | Johns Hopkins University | 25 | 2025-08-01 | 2026-04-13 |
| Developing MRI Technologies for Atrial Fibrillation Atrial Fibrillation (AF) | Enrolling by invitation | The Cleveland Clinic | 50 | 2025-01-16 | 2026-03-23 | |
| MRI Gadopiclenol Enhanced Imaging of CNS Tumors CE MRI on 0.064T Scanner, Gadopiclenol - Image | Withdrawn | Medical University of South Carolina | 2024-12-30 | 2025-02-04 | ||
| Lipiodol Prior to FET (LIFE) Lipiodol® uterine treatment prior to IVF/ICSI - IVF, Frozen Embryo Transfer | Not applicable | Not yet recruiting | Mỹ Đức Hospital | 784 | 2024-08-10 | 2024-08-21 |
| Gadopiclenol vs Gadoxetate MRI for Liver Lesions Radiology, Gadopiclenol - Liver Lesion | Enrolling by invitation | Icahn School of Medicine at Mount Sinai | 23 | 2024-07-01 | 2026-04-22 | |
| Guerbet Liver Fibrosis Metabolic Dysfunction-associated Steatotic Liver Disease | Enrolling by invitation | Icahn School of Medicine at Mount Sinai | 50 | 2024-02-28 | 2026-04-21 | |
| Gadopiclenol in Contrast Enhanced MRI of the Prostate Gadopiclenol - Prostate Cancer | Phase 4 | Suspended | Columbia University | 150 | 2024-02-14 | 2026-07-20 |
| Preoperative Embolization of Hypervascular Head and Neck Tumors to Improve Surgical Outcomes Iodixanol, Angiogram, Arterial Embolization - Malignant Neoplasm in the Head and Neck, Metastatic Malignant Neoplasm in the Head and Neck | Phase 1 | Withdrawn | University of Washington | 2023-12-21 | 2023-12-12 | |
| Performance of Elucirem in DSC-MRI Perfusion of Brain Gliomas Elucirem, Dotarem - Brain Tumor, Primary, Brain Tumor, Recurrent | Phase 3 | Completed | Guerbet | 138 | 2023-09-07 | 2026-01-29 |
| TACE Using Idarubicin Versus Doxorubicin Chemoemulsion in Patients With Hepatocellular Carcinoma IDA-TACE, DOX-TACE - Hepatocellular Carcinoma, Liver Cancer | Phase 2 | Completed | Seoul National University Hospital | 128 | 2023-07-28 | 2026-08-20 |
| Evaluation of Gadopiclenol for Magnetic Resonance Imaging (MRI) in Japanese Adults and Children Gadopiclenol, Comparator (gadobutrol) - Lesion in Body Region, CNS Lesion | Phase 3 | Completed | Guerbet | 240 | 2023-07-21 | 2026-06-25 |
| Safety and Performance of Optivantage Multi-use When Injecting Contrast Media for Contrast Enhanced CT Examination CT examination - Patient Participation | Unknown | Guerbet | 100 | 2022-10-01 | 2022-09-13 | |
| Gadopiclenol Pharmacokinetics, Safety and Efficacy in Children < 2 Years of Age Gadopiclenol - Central Nervous System Diseases, Pediatric Disorder | Phase 2 | Completed | Guerbet | 36 | 2022-09-21 | 2025-10-28 |
| Safety and Performance of Vectorio® in Conventional Trans-Arterial Chemo-Embolization (cTACE): A Post-Market Clinical Follow-up Oncology | Unknown | Guerbet | 50 | 2022-08-30 | 2022-09-15 | |
| Genicular Artery Embolization (GAE) for the Treatment of Chronic Post Knee Arthroplasty Pain Embozene Microspheres - Knee Pain Chronic, Knee Swelling Pain | Not applicable | Withdrawn | Brigham and Women's Hospital | 2022-07-01 | 2023-03-09 | |
| A Zero Acute Kidney Injury Strategy for Percutaneous Coronary Intervention in Patients With ChronicKidney Disease Standard of care Ultra Low Contrast PCI - Acute Kidney Injury, Coronary Artery Disease | Withdrawn | Virginia Commonwealth University | 2022-01-01 | 2022-02-04 | ||
| Pharmacokinetics and Safety of Gadopiclenol in Japanese Healthy Volunteers gadopiclenol, Placebo - Pharmacokinetics | Phase 1 | Completed | Guerbet | 27 | 2021-05-10 | 2021-10-07 |
| Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years Motor Tests, Cognitive Tests, Unenhanced-MRI of the brain - Motor Function, Cognitive Function | Phase 4 | Recruiting | Guerbet | 2076 | 2021-03-24 | 2026-01-22 |
| Safety and Efficacy of a Lipiodol Emulsion for the Embolization of Hypervascularizations in Patients With Knee Pain (LipioJoint1) Lipiodol - Knee Osteoarthritis | Phase 1 | Completed | Assistance Publique - Hôpitaux de Paris | 22 | 2021-03-03 | 2023-08-03 |
Showing 20 of 74. Sign in to see all of them.
Carcinoma, Hepatocellular (9) · Renal Insufficiency (6) · Coronary Artery Disease (5) · Arterial Occlusive Diseases (2) · Brain Neoplasms (2) · Breast Diseases (2) · Breast Neoplasms (2) · Central Nervous System Diseases (2) · Cerebral Arterial Diseases (2) · Liver Neoplasms (2) · Neuroendocrine Tumors (2) · Peripheral Arterial Disease (2) · Prostatic Neoplasms (2) · Acute Kidney Injury (1) · Arteriovenous Malformations (1)
gadoterate meglumine (23) · gadopiclenol (16) · gadobutrol (8) · Ethiodized Oil (4) · iobitridol (4) · iodixanol (4) · Sodium Chloride (3) · gadolinium 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetate (3) · Gadolinium DTPA (2) · Solutions (2) · gadobenic acid (2) · ioversol (2) · Contrast Media (1) · Gadolinium (1) · Idarubicin (1)
United States (36) · France (18) · South Korea (17) · Italy (12) · Germany (10) · Spain (9) · Hungary (8) · Poland (8) · Austria (7) · Belgium (7) · Argentina (4) · Mexico (4) · Canada (3) · Japan (3) · Switzerland (3)
Corinne Dubourdieu, PhD (3) · Eddie Darton, MD (2) · Sara Lewis, MD (2) · Ari Goldberg, MD (1) · Binita Shah, MD, MS (1) · Christoph Lohmann, Professor MD (1) · Christopher Nguyen, PhD (1) · Dipan Shah, MD (1) · Do Lim (1) · Donna R Roberts, MD (1)
PMID 24016489, PMID 25147030, PMID 30016989, PMID 30870257, PMID 31014090, PMID 33053612, PMID 34197356, PMID 35318970, PMID 36042629, PMID 36729404, PMID 37233207, PMID 37462494, PMID 38102013, PMID 38147153
2017 (2), 2018 (1)