23 completed, 10 unknown, 2 not yet recruiting, 1 recruiting. 13 Not applicable, 6 Phase 4, 5 Phase 3, 3 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 13 | Completed 6, Unknown 4, Not yet recruiting 2, Terminated 1 |
| Phase 4 | 6 | Completed 5, Unknown 1 |
| Phase 3 | 5 | Completed 5 |
| Phase 2 | 3 | Completed 2, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
Follow Reflux Esophagitis: new trials by email Literature Review of Reflux Esophagitis trials Research Report on Reflux Esophagitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Prospective Cohort Study on Endoscopic Features of Upper Gastrointestinal Tract at High Altitude (Zaduo County) Sedated gastroscopy - Reflux Esophagitis | Recruiting | Jilin University | 60 | 2025-12-01 | 2026-08-10 | |
| Preliminary Efficacy Analysis of "C" Single Flap Plasty Reconstruction After Laparoscopic Proximal Gastrectomy "C" Single Flap Plasty Reconstruction, Normal Reconstruction - Gastric Cancer, Reflux Esophagitis | Not applicable | Not yet recruiting | Daorong Wang | 50 | 2025-01-01 | 2024-12-19 |
| Preliminary Efficacy Analysis of 'λ+α' Double-Tract Reconstruction After Laparoscopic Proximal Gastrectomy proximal gastrectomy combined with 'λ+α' double-tract anastomosis - Gastric Cancer, Reflux Esophagitis | Not applicable | Unknown | Northern Jiangsu People's Hospital | 60 | 2024-08-01 | 2024-08-15 |
| FundoRing Roux-en-Y Gastric Bypass Versus FundoRing One Anastomosis Gastric Bypass Laparoscopic FundoRing gastric bypass - Obesity, Roux-en-y Anastomosis Site | Not applicable | Completed | The Society of Bariatric and Metabolic Surgeons of Kazakhstan | 200 | 2024-07-04 | 2026-03-20 |
| Protocol for Comparing the Efficacy of Three Reconstruction Methods of the Digestive Tract After Proximal Gastrectomy Kamikawa, STJI, SOFY - Proximal Gastric Adenocarcinoma, Gastrectomy | Not applicable | Not yet recruiting | Changzhi People's Hospital Affiliated to Changzhi Medical College | 180 | 2023-10-01 | 2023-10-05 |
| Jinghua Weikang Capsule in the Treatment of Reflux Esophagitis jinghua weikang capsule - Reflux Esophagitis | Phase 4 | Unknown | The First Affiliated Hospital of Dalian Medical University | 260 | 2023-10-01 | 2023-09-28 |
| Treatment of Reflux With Sleeve Gastrectomy Laparoscopic Sleeve Gastrectomy - Reflux Disease, Gastro-Esophageal, Hiatal Hernia | Not applicable | Unknown | Yusuf Emre ALTUNDAL | 80 | 2023-09-25 | 2023-12-27 |
| Role of ARMA in Selective Subset of Refractory GERD Patients. ARMA, UGI Endoscopy - GERD, Reflux | Not applicable | Completed | Asian Institute of Gastroenterology, India | 50 | 2023-03-30 | 2025-04-04 |
| A Study of Anaprazole Sodium Enteric-coated Tablets in the Treatment of Reflux Esophagitis Anaprazole sodium 40 mg, Anaprazole sodium 60 mg, Rabeprazole sodium 20 mg - Reflux Esophagitis, Gastroesophageal Reflux | Phase 2 | Unknown | Xuanzhu Biopharmaceutical Co., Ltd. | 156 | 2022-12-01 | 2022-11-03 |
| A Novel Endoloop Pre-test to Treat Gastroesophageal Reflux Endoscopic endoloop pre-test treatment - GERD, Reflux Esophagitis | Not applicable | Unknown | Affiliated Hospital to Academy of Military Medical Sciences | 30 | 2022-02-10 | 2022-03-16 |
| The Efficacy and Safety of DWP14012 in Chinese Patients With Reflux Esophagitis DWP14012 - Reflux Esophagitis | Phase 3 | Completed | Daewoong Pharmaceutical Co. LTD. | 332 | 2021-12-30 | 2023-04-14 |
| The Phase III Clinical Trial of X842 Capsules for Reflux Esophagitis X842, X842 Placebo, Lansoprazole - Reflux Esophagitis | Phase 3 | Completed | Jiangsu Sinorda Biomedicine Co., Ltd | 380 | 2021-06-24 | 2025-07-23 |
| Preliminary Efficacy Analysis of Cheng's Giraffe Reconstruction After Proximal Gastrectomy proximal gastrectomy combined with Cheng's Giraffe reconstruction - Gastric Cancer, Reflux Esophagitis | Not applicable | Unknown | Zhejiang Cancer Hospital | 100 | 2020-06-01 | 2020-12-08 |
| Study to Evaluate the Safety and Efficacy of X842 in Patients With Reflux Esophagitis X842, X842 Placebo, Lansoprazole - Reflux Esophagitis | Phase 2 | Completed | Jiangsu Sinorda Biomedicine Co., Ltd | 90 | 2020-01-21 | 2025-07-17 |
| A Study of Esomeplazole (D961H) in Japanese Paediatric Patients With Reflux Esophagitis, Gastric Ulcer or Duodenal Ulcer D961H capsule 10mg, D961H sachet 10mg - Reflux Esophagitis, Gastric Ulcer | Phase 3 | Completed | AstraZeneca | 50 | 2018-07-24 | 2026-03-04 |
| Feasibility of Multi-Spectral Endoscopic Imaging for Detection of Early Neoplasia in Barrett's Oesophagus Endoscopy with Polyscope (Polydiagnost TM) coupled with Multi-Spectral Imaging light-source - Barrett Esophagus, Esophageal Neoplasms | Not applicable | Completed | University of Cambridge | 20 | 2018-01-01 | 2021-04-28 |
| Vonoprazan Study of Investigating the Effect on Sleep Disturbance Associated With Reflux Esophagitis- Exploratory Evaluation Vonoprazan - Reflux Esophagitis | Phase 4 | Completed | Takeda | 3 | 2017-08-02 | 2019-03-29 |
| Special Drug Use Surveillance of Vonoprazan for "Maintenance Therapy of Reflux Esophagitis: Long-term Use" Vonoprazan - Reflux Esophagitis | Completed | Takeda | 1237 | 2016-03-01 | 2025-06-10 | |
| Trial to Assess the Effects of an Antimicrobial Mouthwash on the Esophageal Microbiome Chlorhexidine gluconate - Esophageal Adenocarcinoma, Barrett's Esophagus | Not applicable | Completed | Columbia University | 20 | 2015-08-01 | 2022-09-22 |
| Nexium Capsules S-CEI for Justification of Esomeprazole in Acid Related Disease for Reflux Symptom Healing Based on Patient Clinical Outcomes Reflux Esophagitis | Completed | AstraZeneca | 1595 | 2015-07-07 | 2017-06-21 |
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Esophagitis, Peptic (37) · Gastroesophageal Reflux (13) · Barrett Esophagus (3) · Stomach Neoplasms (3) · Duodenal Ulcer (2) · Esophagitis (2) · Heartburn (2) · Hernia, Hiatal (2) · Stomach Ulcer (2) · Adenocarcinoma (1) · Adenocarcinoma Of Esophagus (1) · Altitude Sickness (1) · Deglutition Disorders (1) · Esophageal Diseases (1) · Esophageal Motility Disorders (1)
Digestive System Diseases (37) · Duodenal Diseases (37) · Gastroenteritis (37) · Intestinal Diseases (37) · Peptic Ulcer (37) · Stomach Diseases (37) · Esophageal Diseases (36) · Gastrointestinal Diseases (36) · Esophagitis (35) · Deglutition Disorders (12) · Esophageal Motility Disorders (12) · Pathological Conditions, Signs and Symptoms (8) · Neoplasms (6) · Signs and Symptoms (5) · Digestive System Neoplasms (4)
Esomeprazole (6) · Lansoprazole (3) · Rabeprazole (3) · 1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine (2) · Omeprazole (2) · Dosage Forms (1) · Endoscopy (1) · chlorhexidine gluconate (1) · fexuprazan (1) · jinghua weikang (1)
AstraZeneca (8) · National Taiwan University Hospital (3) · Jiangsu Sinorda Biomedicine Co., Ltd (2) · Takeda (2) · Affiliated Hospital to Academy of Military Medical Sciences (1) · Asian Institute of Gastroenterology, India (1) · Changzhi People's Hospital Affiliated to Changzhi Medical College (1) · Chong Kun Dang Pharmaceutical (1) · Columbia University (1) · Daewoong Pharmaceutical Co. LTD. (1) · Dallas VA Medical Center (1) · Daorong Wang (1) · Janssen Korea, Ltd., Korea (1) · Jian-Kun Hu (1) · Jilin University (1)
China (10) · Japan (7) · South Korea (4) · United States (4) · Taiwan (3) · India (1) · Kazakhstan (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Bor-Ru Lin, M.D. (2) · Maotsugu Oyama, MD, PhD (2) · Pingsheng Hu, Ph.D (2) · Digvijay Chavan (1) · Dong Yang, Doctor (1) · Jongsun Rew, Ph.D (1) · Julian A. Abrams, MD, MS (1) · Makiko Abe (1) · Masataka Date (1) · Megumi Inoue, MD, PhD (1) · Myung Gyy Choi, M.D., Ph.D. (1) · Neeraj Singla, MD (1)
PMID 17305763, PMID 21356058, PMID 27187303, PMID 27694141, PMID 32010745, PMID 33512805, PMID 34628734, PMID 34754155, PMID 36109362, PMID 38251791, PMID 39836012, PMID 41982134
2018 (1), R01DK063621 (1)