66 completed, 31 unknown, 20 recruiting, 9 terminated. 38 Phase 2, 37 Not applicable, 23 Phase 3, 12 Phase 1, 2 Early Phase 1.
Follow Radiation Toxicity: new trials by email Literature Review of Radiation Toxicity trials Research Report on Radiation Toxicity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oral Care Program for Mouth Side Effects During Head and Neck Radiation Therapy ORAL CARE PRODUCT KIT - Head and Neck Cancer (H&N), Oral Mucositis (Ulcerative) Due to Radiation | Not applicable | Not yet recruiting | UNCANCER LLC | 50 | 2026-11-01 | 2026-10-21 |
| Retrospective Observational Study of Oral Complications and Quality of Life in Head and Neck Cancer Patients Treated With Radiotherapy or Chemoradiotherapy. Oral Mucositis, Quality of Life | Not yet recruiting | Mucosa Innovations, S.L. | 60 | 2026-08-01 | 2026-07-31 | |
| DENTOFACIAL-PBT Stage 2 - Feasibility Study Orthopantomogram (or a set of Lateral Oblique Radiographs) - Head and Neck Cancer, Radiotherapy Side Effect | Enrolling by invitation | Manchester University NHS Foundation Trust | 255 | 2026-01-16 | 2026-01-26 | |
| Gut Microbiome in Gynecological Cancer Patients With Pelvic Toxicity: Controls Versus Ozone Treatment. (MicrOzoGineTox) Pelvic Toxicity, Radiation Toxicity | Recruiting | Bernardino Clavo, MD, PhD | 38 | 2026-01-15 | 2026-09-23 | |
| Patients Referred to the Chronic Pain Unit for Palliative Treatment With Ozone Therapy Between 2026 and 2029. Ozone Therapy - Chemotherapy-Induced Peripheral Neuropathy, Radiation Toxicity | Recruiting | Bernardino Clavo, MD, PhD | 120 | 2026-01-14 | 2026-09-23 | |
| Curatively Intended Thoracic Reirradiation Radiotherapy - Radiotherapy Side Effect, Radiation Toxicity | Recruiting | University of Aarhus | 500 | 2025-10-10 | 2026-03-04 | |
| Bevacizumab Versus Corticosteroids as First-line Treatment in Patients With Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain Metastases Bevacizumab, Dexamethasone - Radiation Necrosis, High Grade Glioma (III or IV) | Phase 3 | Recruiting | The Netherlands Cancer Institute | 408 | 2025-06-19 | 2026-07-13 |
| A MAajor RAdiation-based PCI Study in STEMI and NSTEMI Non Complex PCI, Complex PCI - Myocardial Infarction (MI), Radiation Toxicity | Active not recruiting | Centre Cardiologique du Nord | 15630 | 2025-03-01 | 2026-08-21 | |
| Feasibility of the Maastro Applicator in Rectal Cancer Maastro applicator - Rectal Cancer, Feasibility | Not applicable | Active not recruiting | Maastricht Radiation Oncology | 10 | 2024-08-27 | 2025-08-14 |
| The Clinical Study of Post-operative Proton Radiotherapy for Thymus Tumor Proton radiotherapy, combined platinum based chemotherapy - Thymus Epithelial Tumor, Proton Radiotherapy | Phase 2 | Recruiting | Jian Chen | 55 | 2024-05-06 | 2025-06-13 |
| A Study to Determine the Preferred Dose of the Drug, Lisinopril, for Preventing Urinary Toxicity Following Radiotherapy for Prostate Cancer Lisinopril Tablets - Prostate Cancer, Radiation Toxicity | Early Phase 1 | Recruiting | University of Rochester | 30 | 2024-02-20 | 2026-07-23 |
| A Novel Target Delineation Scheme in High-grade Glioma Patients: a Randomized Single-blind Clinical Trial reduced target volume, EORTC (European organisation for research and treatment of cancer) target volume - Radiation Toxicity, MRI Simulated Positioning | Not applicable | Recruiting | Zhujiang Hospital | 88 | 2024-02-18 | 2024-03-15 |
| Pre-Rehabilitation for Female Patients Undergoing Pelvic Radiotherapy Pelvic health therapy, Dilator feasability - Dyspareunia, Pelvic Pain | Not applicable | Recruiting | Indiana University | 20 | 2024-01-16 | 2026-09-18 |
| The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study Short Chain Fatty Acid, Tapioca Flour - Toxicity, Radiation Toxicity | Phase 1 / Phase 2 | Recruiting | UNC Lineberger Comprehensive Cancer Center | 122 | 2023-12-15 | 2026-10-05 |
| Integrative Molecular Analysis of Individual Radiosensitivity in Pediatric Oncology Blood sample - Radiosensitivity, Pediatric Cancer | Not applicable | Recruiting | Neolys | 100 | 2023-12-02 | 2024-11-22 |
| Atrial Fibrillation and Other Cardiac Arrhythmias and Diseases After Radiotherapy for Breast Cancer : Watch Your HeaRT Screening for atrial fibrillation and other cardiac arrhythmias and diseases - Breast Cancer, Radiation Toxicity | Unknown | Sophie JACOB | 200 | 2023-10-25 | 2023-11-08 | |
| Neurocognitive Impact of Different Irradiation Modalities for Patients With Grade I-II Skull Base Meningioma: Normo-fractionated intensity-modulated brain irradiation with or without stereotactic positioning, Hypo-fractionated stereotactic brain irradiation, Normo-fractionated proton therapy brain irradiation - Meningioma, Radiation Toxicity | Not applicable | Recruiting | Centre Francois Baclesse | 108 | 2023-09-13 | 2025-06-24 |
| Precision Radiotherapy for Tumours Using Magnetic Resonance-guided Linear Accelerator (MR-Linac) MR-Linac - Overall Response Rate, Oncology | Recruiting | The Second Affiliated Hospital of Hainan Medical University | 3000 | 2023-08-19 | 2025-02-13 | |
| Stereotactic Arrhythmia Radioablation for Ventricular Tachycardia (StAR-VT) stereotactic body radiotherapy, 20 Gy in 1 fraction - Ventricular Tachycardia, Arrhythmia | Phase 2 | Enrolling by invitation | McGill University Health Centre/Research Institute of the McGill University Health Centre | 9 | 2023-07-01 | 2025-03-18 |
| Deep-sea Fish Oil for Prevention of Acute Radiation-induced Esophagitis Deep-sea fish oil, Placebo - Radiation Toxicity, Esophagitis | Phase 2 | Unknown | First Affiliated Hospital of Chengdu Medical College | 120 | 2023-01-15 | 2024-05-01 |
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Radiation Injuries (141) · Head and Neck Neoplasms (27) · Breast Neoplasms (17) · Brain Neoplasms (14) · Prostatic Neoplasms (14) · Lung Neoplasms (13) · Neoplasms (12) · Uterine Cervical Neoplasms (12) · Squamous Cell Carcinoma of Head and Neck (11) · Drug-Related Side Effects and Adverse Reactions (9) · Salivary Gland Neoplasms (8) · Xerostomia (8) · Carcinoma, Non-Small-Cell Lung (7) · Endometrial Neoplasms (6) · Nasopharyngeal Neoplasms (6)
Wounds and Injuries (141) · Neoplasms (105) · Neoplasms by Site (105) · Pathological Conditions, Signs and Symptoms (36) · Neoplasms by Histologic Type (32) · Genital Diseases (26) · Neoplasms, Glandular and Epithelial (26) · Pathologic Processes (26) · Urogenital Diseases (26) · Urogenital Neoplasms (25) · Nervous System Diseases (24) · Respiratory Tract Diseases (23) · Respiratory Tract Neoplasms (21) · Skin and Connective Tissue Diseases (21) · Stomatognathic Diseases (21)
Radiotherapy (23) · Cisplatin (11) · Amifostine (10) · Radiotherapy, Intensity-Modulated (9) · Paclitaxel (6) · Carboplatin (4) · Chemotherapy, Adjuvant (4) · Etoposide (4) · Brachytherapy (3) · Diet Therapy (3) · Donepezil (3) · Filgrastim (3) · Magnetic Resonance Spectroscopy (3) · Neuropsychological Tests (3) · Radiosurgery (3)
Radiation Therapy Oncology Group (15) · Alliance for Clinical Trials in Oncology (5) · Wake Forest University Health Sciences (5) · Case Comprehensive Cancer Center (4) · Royal Marsden NHS Foundation Trust (4) · University of Aarhus (4) · Bernardino Clavo, MD, PhD (3) · National Cancer Institute (NCI) (3) · UMC Utrecht (3) · Abramson Cancer Center at Penn Medicine (2) · Cancer Trials Ireland (2) · Centre Francois Baclesse, Luxembourg (2) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (2) · King Hussein Cancer Center (2) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (2)
United States (61) · Canada (16) · Denmark (10) · United Kingdom (9) · China (8) · France (7) · Spain (6) · Italy (5) · Netherlands (5) · Belgium (4) · Ireland (3) · Cyprus (2) · Egypt (2) · Jordan (2) · Mexico (2)
Scott Okuno, MD (3) · Aminah Jatoi, MD (2) · Benjamin Movsas, MD (2) · Bernardino Clavo, MD, PhD (2) · Chris Nutting (2) · Helena M Verkooijen, MD, PhD (2) · James J. Urbanic, MD (2) · Stewart Gaede, PhD (2) · Alan Dal Pra, MD (1) · Alessio G Morganti, MD (1) · Alessio G. Morganti, MD (1) · Alex A. Adjei, MD, PhD (1) · Alexander Lin, MD (1) · Amy LeJeune, MS, RD (1)
PMID 15992242, PMID 22105041, PMID 23102757, PMID 23215625, PMID 26357522, PMID 30271455, PMID 32379556, PMID 33738491, PMID 11917283, PMID 12800204, PMID 15050309, PMID 15480814, PMID 15800308, PMID 16015544, PMID 16549835, PMID 16823067, PMID 17293228, PMID 17336213, PMID 17394940, PMID 17398031, PMID 17418968, PMID 17869014, PMID 18501528, PMID 18973181, PMID 19332518, PMID 19395195, PMID 19409733, PMID 19515514, PMID 19540060, PMID 19564532, PMID 19596158, PMID 19634161, PMID 19858383, PMID 19910132, PMID 20441239, PMID 20610037, PMID 20800381, PMID 20888137, PMID 21109081, PMID 21235716, PMID 21236730, PMID 21656740, PMID 21892091, PMID 22248793, PMID 22354624, PMID 22541957, PMID 22580119, PMID 23477890, PMID 24403270, PMID 24619017
U10CA081851 (3), 2014 (1), N01CM62202 (1), P30CA006516 (1), P30CA012197 (1), P30CA014520 (1), P30CA015083 (1), P30CA016042 (1), P30CA016672 (1), P30CA023074 (1), P30CA043703 (1), R01CA107080 (1), U10CA027469 (1)