6 completed, 3 unknown, 1 active not recruiting, 1 recruiting. 12 Phase 1, 10 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 12 | Completed 6, Unknown 3, Active not recruiting 1, Recruiting 1, Terminated 1 |
| Phase 2 | 10 | Completed 5, Unknown 3, Active not recruiting 1, Recruiting 1 |
Follow Radiation Toxicity: new trials by email Literature Review of Radiation Toxicity trials Research Report on Radiation Toxicity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study Short Chain Fatty Acid, Tapioca Flour - Toxicity, Radiation Toxicity | Phase 1 / Phase 2 | Recruiting | UNC Lineberger Comprehensive Cancer Center | 122 | 2023-12-15 | 2026-10-05 |
| Hypo-Combi Trial: Hypofractionated EBRT Plus HDR-BT Boost for Prostate Cancer External beam radiation therapy, High-dose-rate brachytherapy, Goserelin 10.8 mg - Prostate Adenocarcinoma, Radiation Toxicity | Phase 1 / Phase 2 | Active not recruiting | German Oncology Center, Cyprus | 40 | 2021-08-01 | 2026-09-17 |
| Efficacy of the Mepitel® Film on the Prevention of Radiodermatitis in the Inguinal Fold. Mepitel® film, Flamigel® - Radiodermatitis, Radiation Toxicity | Phase 1 / Phase 2 | Unknown | Jules Bordet Institute | 35 | 2021-01-01 | 2020-11-05 |
| Mesenchymal Stem Cells for Radiation-induced Xerostomia Autologous adipose-derived mesenchymal stem/stromal cells, Placebo - Radiation Toxicity, Xerostomia Due to Radiotherapy | Phase 1 / Phase 2 | Unknown | Copenhagen University Hospital, Rigshospitalet | 30 | 2020-08-01 | 2020-10-22 |
| Feasibility of Combined Focused Ultrasound and Radiotherapy Treatment in Patients With Painful Bone Metastasis combined radiotherapy and MR-HIFU - Bone Metastases, Bone Neoplasm | Phase 1 / Phase 2 | Completed | UMC Utrecht | 10 | 2019-04-11 | 2024-02-07 |
| Phone or Email Reminder in Increasing Vaginal Dilator Use in Patients With Gynecologic Cancers Undergoing Brachytherapy survey administration, computer-assisted intervention, telephone-based intervention - Cervical Cancer, Endometrial Cancer | Phase 1 | Completed | Stanford University | 72 | 2014-09-01 | 2021-08-17 |
| Flaxseed Supplement in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Undergoing Chemotherapy and Radiation Therapy flaxseed, placebo - Lung Cancer, Radiation Toxicity | Phase 1 | Terminated | Abramson Cancer Center at Penn Medicine | 48 | 2007-12-01 | 2020-04-02 |
| Radiation Therapy and Cisplatin With or Without Amifostine for Patients With Stage IIIB or IVA Cervical Cancer Amifostine trihydrate, Cisplatin, Intracavitary brachytherapy - Cervical Cancer, Radiation Toxicity | Phase 1 / Phase 2 | Completed | Radiation Therapy Oncology Group | 45 | 2001-08-01 | 2015-01-07 |
| Radiation Therapy in Treating Patients With Stage II or Stage III Oropharyngeal Cancer radioprotection, radiation therapy - Head and Neck Cancer, Radiation Toxicity | Phase 1 / Phase 2 | Completed | Radiation Therapy Oncology Group | 2001-02-01 | 2020-10-22 | |
| Combination Chemotherapy and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer filgrastim, amifostine trihydrate, cisplatin - Drug/Agent Toxicity by Tissue/Organ, Lung Cancer | Phase 1 / Phase 2 | Completed | Alliance for Clinical Trials in Oncology | 73 | 2001-02-01 | 2016-07-06 |
| Amifostine Plus Chemotherapy and Radiation Therapy in Treating Patients With Advanced, Unresectable Head and Neck Cancer amifostine trihydrate, cisplatin, paclitaxel - Drug/Agent Toxicity by Tissue/Organ, Head and Neck Cancer | Phase 1 / Phase 2 | Unknown | University of Illinois at Chicago | 46 | 1997-12-01 | 2013-12-04 |
| Monoclonal Antibody Therapy in Treating Patients With Leukemia pentetic acid calcium, yttrium Y 90 daclizumab - Lymphoma, Radiation Toxicity | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 1996-10-01 | 2013-06-20 |
Radiation Injuries (12) · Drug-Related Side Effects and Adverse Reactions (2) · Head and Neck Neoplasms (2) · Lung Neoplasms (2) · Squamous Cell Carcinoma of Head and Neck (2) · Uterine Cervical Neoplasms (2) · Bone Neoplasms (1) · Carcinoma, Non-Small-Cell Lung (1) · Endometrial Neoplasms (1) · Gastrointestinal Neoplasms (1) · Hypopharyngeal Neoplasms (1) · Laryngeal Neoplasms (1) · Long Term Adverse Effects (1) · Lymphoma (1) · Mouth Neoplasms (1)
Wounds and Injuries (12) · Neoplasms (9) · Neoplasms by Site (9) · Genital Diseases (3) · Neoplasms by Histologic Type (3) · Respiratory Tract Diseases (3) · Respiratory Tract Neoplasms (3) · Urogenital Diseases (3) · Urogenital Neoplasms (3) · Carcinoma (2) · Carcinoma, Squamous Cell (2) · Chemically-Induced Disorders (2) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Genital Diseases, Female (2)
Amifostine (3) · Cisplatin (3) · Radiotherapy (3) · Paclitaxel (2) · Androgen Antagonists (1) · Brachytherapy (1) · Butyric Acid (1) · Daclizumab (1) · Etoposide (1) · Fatty Acids, Volatile (1) · Filgrastim (1) · Goserelin (1) · Linseed Oil (1) · Pentetic Acid (1) · Radiation Protection (1)
Radiation Therapy Oncology Group (2) · Abramson Cancer Center at Penn Medicine (1) · Alliance for Clinical Trials in Oncology (1) · Copenhagen University Hospital, Rigshospitalet (1) · German Oncology Center, Cyprus (1) · Jules Bordet Institute (1) · National Cancer Institute (NCI) (1) · Stanford University (1) · UMC Utrecht (1) · UNC Lineberger Comprehensive Cancer Center (1) · University of Illinois at Chicago (1)
United States (8) · Canada (1) · Cyprus (1) · Denmark (1) · Netherlands (1)
Alexander Lin, MD (1) · Avraham Eisbruch, MD (1) · Charlotte Lynggaard, MD (1) · Elizabeth Kidd (1) · Fred R. Rosen, MD (1) · Helena M Verkooijen, MD, PhD (1) · Iosif Strouthos, MD PhD (1) · Scott Okuno, MD (1) · Shivani Sud, MD (1) · Thomas A. Waldmann, MD (1) · William Small, MD (1)
PMID 17336213, PMID 17398031, PMID 19540060, PMID 21892091, PMID 36925074
2014 (1)