24 completed, 6 unknown, 4 terminated, 2 recruiting. 38 Phase 2, 10 Phase 1, 1 Phase 3.
Follow Radiation Toxicity: new trials by email Literature Review of Radiation Toxicity trials Research Report on Radiation Toxicity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Clinical Study of Post-operative Proton Radiotherapy for Thymus Tumor Proton radiotherapy, combined platinum based chemotherapy - Thymus Epithelial Tumor, Proton Radiotherapy | Phase 2 | Recruiting | Jian Chen | 55 | 2024-05-06 | 2025-06-13 |
| The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study Short Chain Fatty Acid, Tapioca Flour - Toxicity, Radiation Toxicity | Phase 1 / Phase 2 | Recruiting | UNC Lineberger Comprehensive Cancer Center | 122 | 2023-12-15 | 2026-10-05 |
| Stereotactic Arrhythmia Radioablation for Ventricular Tachycardia (StAR-VT) stereotactic body radiotherapy, 20 Gy in 1 fraction - Ventricular Tachycardia, Arrhythmia | Phase 2 | Enrolling by invitation | McGill University Health Centre/Research Institute of the McGill University Health Centre | 9 | 2023-07-01 | 2025-03-18 |
| Deep-sea Fish Oil for Prevention of Acute Radiation-induced Esophagitis Deep-sea fish oil, Placebo - Radiation Toxicity, Esophagitis | Phase 2 | Unknown | First Affiliated Hospital of Chengdu Medical College | 120 | 2023-01-15 | 2024-05-01 |
| Hypo-Combi Trial: Hypofractionated EBRT Plus HDR-BT Boost for Prostate Cancer External beam radiation therapy, High-dose-rate brachytherapy, Goserelin 10.8 mg - Prostate Adenocarcinoma, Radiation Toxicity | Phase 1 / Phase 2 | Active not recruiting | German Oncology Center, Cyprus | 40 | 2021-08-01 | 2026-09-17 |
| Efficacy of the Mepitel® Film on the Prevention of Radiodermatitis in the Inguinal Fold. Mepitel® film, Flamigel® - Radiodermatitis, Radiation Toxicity | Phase 1 / Phase 2 | Unknown | Jules Bordet Institute | 35 | 2021-01-01 | 2020-11-05 |
| Mesenchymal Stem Cells for Radiation-induced Xerostomia Autologous adipose-derived mesenchymal stem/stromal cells, Placebo - Radiation Toxicity, Xerostomia Due to Radiotherapy | Phase 1 / Phase 2 | Unknown | Copenhagen University Hospital, Rigshospitalet | 30 | 2020-08-01 | 2020-10-22 |
| Feasibility of Combined Focused Ultrasound and Radiotherapy Treatment in Patients With Painful Bone Metastasis combined radiotherapy and MR-HIFU - Bone Metastases, Bone Neoplasm | Phase 1 / Phase 2 | Completed | UMC Utrecht | 10 | 2019-04-11 | 2024-02-07 |
| Photobiomodulation for Breast Cancer Radiodermatitis Photobiomodulation - Breast Cancer, Radiodermatitis | Phase 2 / Phase 3 | Completed | AC Camargo Cancer Center | 48 | 2018-09-26 | 2021-08-13 |
| Re-irradiation for Pelvic Recurrences in Rectal Cancer Patients Hyperfractionated external beam radiation - Rectal Cancer, Recurrence | Phase 2 | Completed | Aarhus University Hospital | 16 | 2015-01-01 | 2023-04-18 |
| Rituximab, Methotrexate, Vincristine Sulfate, Procarbazine Hydrochloride, and Cytarabine With or Without Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma Rituximab, Cytarabine, Methotrexate - Chemotherapeutic Agent Toxicity, Cognitive/Functional Effects | Phase 2 | Completed | Radiation Therapy Oncology Group | 91 | 2011-09-01 | 2023-07-20 |
| Radiation Therapy in Treating Patients With Prostate Cancer 36.25 Gy IMRT, 51.6 Gy IMRT - Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment | Phase 2 | Completed | Radiation Therapy Oncology Group | 255 | 2011-09-01 | 2022-06-09 |
| L-Arginine Supplementation With or Without Enzyme Inhibitors Treating Erectile Function of Prostate Cancer Survivors Placebo, Oral L-Arginine - Male Erectile Disorder, Prostate Cancer | Phase 2 | Completed | Wake Forest University Health Sciences | 140 | 2010-10-01 | 2021-09-28 |
| Alkaline Water in Reducing Skin Toxicity in Women With Breast Cancer Undergoing Radiation Therapy alkaline water, distilled water, external beam radiation therapy (EBRT) - Radiation Toxicity, Recurrent Breast Cancer | Phase 2 | Completed | Case Comprehensive Cancer Center | 45 | 2010-05-01 | 2015-06-18 |
| Prospective Randomised Phase II Trial Evaluating Adjuvant Pelvic Radiotherapy Using Either IMRT or 3-Dimensional Planning for Endometrial Cancer. ICORG 09-06 45 Gy/25 fractions - Endometrial Cancer, Gastrointestinal Complications | Phase 2 | Terminated | Cancer Trials Ireland | 92 | 2010-03-01 | 2026-04-13 |
| Selenomethionine in Reducing Mucositis in Patients With Locally Advanced Head and Neck Cancer Who Are Receiving Cisplatin and Radiation Therapy selenomethionine, placebo, cisplatin - Chemotherapeutic Agent Toxicity, Mucositis | Phase 2 | Terminated | Roswell Park Cancer Institute | 18 | 2009-06-01 | 2014-08-22 |
| Lovastatin in Reducing Side Effects After Radiation Therapy in Women With Breast Cancer lovastatin, questionnaire administration, adjuvant therapy - Breast Cancer, Radiation Toxicity | Phase 2 | Terminated | Virginia Commonwealth University | 3 | 2009-04-01 | 2013-06-20 |
| Image-Guided Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Shoulder, Arm, Hip, or Leg Chemotherapy, Radiation therapy, Surgery - Lymphedema, Musculoskeletal Complications | Phase 2 | Completed | Radiation Therapy Oncology Group | 98 | 2008-03-01 | 2019-06-12 |
| Spinal Cord Compression Re-Treat Study Cumulative BED ≤ 100, Cumulative BED ≤ 130 Gy2 - Pain, Radiation Toxicity | Phase 2 | Completed | Cancer Trials Ireland | 22 | 2007-10-01 | 2019-07-29 |
| Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer bevacizumab, placebo, magnetic resonance imaging - Adult Anaplastic Astrocytoma, Adult Anaplastic Ependymoma | Phase 2 | Completed | National Cancer Institute (NCI) | 11 | 2007-06-01 | 2014-05-09 |
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Radiation Injuries (38) · Head and Neck Neoplasms (8) · Drug-Related Side Effects and Adverse Reactions (7) · Squamous Cell Carcinoma of Head and Neck (7) · Breast Neoplasms (4) · Prostatic Neoplasms (4) · Xerostomia (4) · Brain Neoplasms (3) · Lung Neoplasms (3) · Lymphoma (3) · Astrocytoma (2) · Choroid Plexus Neoplasms (2) · Ependymoma (2) · Glioma (2) · Laryngeal Neoplasms (2)
Wounds and Injuries (38) · Neoplasms (31) · Neoplasms by Site (29) · Neoplasms by Histologic Type (13) · Neoplasms, Glandular and Epithelial (9) · Carcinoma (8) · Chemically-Induced Disorders (8) · Pathological Conditions, Signs and Symptoms (8) · Carcinoma, Squamous Cell (7) · Pathologic Processes (7) · Stomatognathic Diseases (7) · Genital Diseases (6) · Mouth Diseases (6) · Salivary Gland Diseases (6) · Urogenital Diseases (6)
Radiotherapy (13) · Amifostine (9) · Cisplatin (9) · Etoposide (4) · Paclitaxel (4) · Carboplatin (2) · Filgrastim (2) · Radiation (2) · Androgen Antagonists (1) · ArginMax (1) · Arginine (1) · Bevacizumab (1) · Brachytherapy (1) · Butyric Acid (1) · Chemotherapy, Adjuvant (1)
Radiation Therapy Oncology Group (8) · Cancer Trials Ireland (2) · National Cancer Institute (NCI) (2) · Wake Forest University Health Sciences (2) · AC Camargo Cancer Center (1) · Aarhus University Hospital (1) · Alliance for Clinical Trials in Oncology (1) · Case Comprehensive Cancer Center (1) · Copenhagen University Hospital, Rigshospitalet (1) · Dana-Farber Cancer Institute (1) · European Organisation for Research and Treatment of Cancer - EORTC (1) · First Affiliated Hospital of Chengdu Medical College (1) · German Oncology Center, Cyprus (1) · Jian Chen (1) · Jonsson Comprehensive Cancer Center (1)
United States (23) · Canada (6) · China (2) · Denmark (2) · Ireland (2) · United Kingdom (2) · Belgium (1) · Brazil (1) · Cyprus (1) · France (1) · Hungary (1) · Israel (1) · Italy (1) · Netherlands (1) · New Zealand (1)
Scott Okuno, MD (2) · Antonio Omuro, MD (1) · Anurag Singh (1) · Avraham Eisbruch, MD (1) · Burton L. Eisenberg, MD (1) · Charles Gillham, Dr (1) · Charles Kunos, MD (1) · Charlotte Lynggaard, MD (1) · Christos E. Emmanouilides, MD (1) · David G. Kirsch, MD, PhD (1) · Dean L. McCarley, MD (1) · Dian Wang, MD, PhD (1) · Edward G. Shaw, MD (1) · Fred R. Rosen, MD (1)
PMID 16549835, PMID 16823067, PMID 17336213, PMID 17398031, PMID 17418968, PMID 19540060, PMID 19564532, PMID 19634161, PMID 20441239, PMID 21892091, PMID 22541957, PMID 24619017, PMID 25667281, PMID 36482188, PMID 36925074, PMID 36995690
U10CA081851 (2), 2014 (1), N01CM62202 (1), P30CA006516 (1), P30CA016672 (1), P30CA023074 (1)