59 completed, 21 unknown, 15 recruiting, 10 terminated. 59 Not applicable, 27 Phase 2, 18 Phase 3, 13 Phase 1, 3 Early Phase 1.
Follow Radiodermatitis: new trials by email Literature Review of Radiodermatitis trials Research Report on Radiodermatitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oral or Topical Catechins for Radiation Dermatitis Epicatechin, Epigallocatechin Gallate (EGCG), Microcrystalline Cellulose NF (placebo) - Radiation Dermatitis Acute, Radiation Dermatitis | Phase 3 | Enrolling by invitation | CARLOS FRANCISCO SAAVEDRA GARCIA | 162 | 2026-10-01 | 2026-09-11 |
| Topical Boswellia Serrata 2% to Prevent Radiation Dermatitis in Head and Neck Cancer Boswellia serrata 2% topical cream - Head and Neck Neoplasms, Radiodermatitis | Not applicable | Recruiting | Youssef Hashem Hafez | 60 | 2026-08-18 | 2026-08-21 |
| Artificial Intelligence Powered Digital Education Based on the Neuman Systems Model for Breast Cancer Patients Receiving Radiotherap Neuman-Based AI-Supported Digital Education Program, Standard Care (in control arm) - Breast Cancer, Radiodermatitis | Not applicable | Not yet recruiting | Ataturk University | 38 | 2026-08-01 | 2026-06-16 |
| Superoxide Dismutase Skin Spray for the Prevention of Acute Radiation Dermatitis in Head and Neck Cancer A topical superoxide dismutase skin spray, Placebo Spray - Radiation-induced Dermatitis | Phase 2 | Not yet recruiting | West China Hospital | 140 | 2026-07-15 | 2026-07-15 |
| Polarized Light Therapy for Radiation Dermatitis in Breast Cancer Polarized Polychromatic Light Therapy, Standard Skin Care - Radio Dermatitis, Polarized Light | Not applicable | Recruiting | Beni-Suef University | 60 | 2026-05-21 | 2026-05-26 |
| Effectiveness of 0.9% Normal Saline Soaking in Managing Acute Radiation Dermatitis Normal Saline Soaks (0.9% Sodium Chloride) - Acute Radiation Dermatitis, Head and Neck Cancer (H&N) | Not applicable | Not yet recruiting | King Hussein Cancer Center | 150 | 2026-05-01 | 2026-04-27 |
| Topical Periplaneta Americana-Derived Meilian Fuxin Liquid for Radiation Dermatitis Topical application of Periplaneta americana-derived Meilian Fuxin Solution, Topical application of placebo, Radiotherapy - Radiation-induced Dermatitis | Phase 2 / Phase 3 | Recruiting | West China Hospital | 60 | 2026-03-01 | 2026-03-25 |
| Adapalene Gel for Acute Radiation-Induced Skin Injury Adapalene gel 0.1%, Biafine topical emulsion - Dermatitis, Radiation-Induced, Adapalene | Early Phase 1 | Recruiting | Yunnan Cancer Hospital | 50 | 2026-03-01 | 2026-10-21 |
| Efficacy of Superoxide Dismutase Spray in Preventing Radiation Dermatitis in Patients With Head and Neck Cancer . Placebo Spray, SOD spray - Radiation Dermatitis | Not applicable | Withdrawn | West China Hospital | 2026-02-10 | 2026-06-23 | |
| Efficacy of Superoxide Dismutase in Preventing Radiation Dermatitis in Patients With Head and Neck Cancer . Saline Spray, SOD spray - Radiation Dermatitis | Not applicable | Withdrawn | West China Hospital | 2026-02-04 | 2026-06-23 | |
| Taurine's Therapeutic Effect on Acute Radiation-induced Oral Mucositis and Dermatitis Taurine granule, Placebo granule - Radiation Induced Oral Mucositis, Radiodermatitis | Phase 2 | Recruiting | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | 160 | 2025-11-24 | 2026-07-23 |
| Mepitel Film Breast Breast Cancer, Radiation Dermatitis | Recruiting | National University Hospital, Singapore | 60 | 2025-11-12 | 2026-07-27 | |
| ROS-Scavenging Nanozyme Combined With Thermotherapy Alleviate Radiation Dermatitis in Patients With Head and Neck Cancer Photo-responsive nanozyme - Radiation Dermatitis | Not applicable | Recruiting | West China Hospital | 5 | 2025-07-25 | 2026-04-15 |
| ROS-scavenging Amino Acid-derived Lipids for the Prevention and Treatment of Radiation Dermatitis in Patients With Head and Neck Cancer Amino acid-derived lipids, standard of care - Radiation Dermatitis | Not applicable | Recruiting | West China Hospital | 40 | 2025-07-23 | 2026-04-15 |
| Novel ROS-scavenging Nanoenzymes for the Treatment of Radiation Dermatitis in Patients With Head and Neck Cancer ROS-scavenging Nanoenzymes, Standard of care - Radiation Dermatitis | Not applicable | Recruiting | West China Hospital | 30 | 2025-07-15 | 2025-08-07 |
| M-PART in Head and Neck Cancer Patients Treated With KeraStat Cream for Acute Radiation Dermatitis KeraStat cream, M-PART Assessments via MyCap, Clinical Assessments - Radiation Dermatitis | Not applicable | Completed | Wake Forest University Health Sciences | 16 | 2025-05-08 | 2026-07-06 |
| Photobiomodulation in Radiodermatitis in People With Breast Cancer Photobiomodulation, Sham Control - Breast Cancer, Radio Dermatitis | Not applicable | Not yet recruiting | Instituto Nacional de Cancer, Brazil | 148 | 2025-05-01 | 2025-05-25 |
| Modulating the Skin Microbiome to Prevent Radiation Dermatitis in Breast Cancer Skin Repairing Cream, Cetaphil® Moisturizing Cream as Inactive Control - Skin Microbiome, Breast Cancer | Phase 3 | Recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 326 | 2025-04-10 | 2025-07-15 |
| Topical Betamethasone Versus Moisturizer in Preventing Radiation Dermatitis in Large-Breasted Patients Treated in the Prone Position Topical Betamethasone - Breast Cancer, Radiation Dermatitis | Phase 3 | Recruiting | Sunnybrook Health Sciences Centre | 276 | 2025-02-26 | 2025-05-21 |
| Topical Diclofenac for Prevention of Radiation-induced Dermatitis Diclofenac Sodium Gel, Placebo gel - Head and Neck Tumor, Breast Cancer | Not applicable | Recruiting | The Second Affiliated Hospital of Hainan Medical University | 156 | 2025-02-13 | 2026-04-03 |
Showing 20 of 125. Sign in to see all of them.
Breast Neoplasms (54) · Head and Neck Neoplasms (18) · Radiation Injuries (11) · Dermatitis (8) · Neoplasms (7) · Skin Diseases (3) · Stomatitis (3) · Eczema (2) · Erythema (2) · Nasopharyngeal Carcinoma (2) · Pain (2) · Alopecia (1) · Breast Carcinoma In Situ (1) · Fibrosis (1)
Skin and Connective Tissue Diseases (125) · Wounds and Injuries (124) · Skin Diseases (122) · Dermatitis (117) · Radiation Injuries (114) · Neoplasms by Site (69) · Neoplasms (67) · Breast Diseases (54) · Pathological Conditions, Signs and Symptoms (8) · Stomatognathic Diseases (5) · Neoplasms by Histologic Type (4) · Signs and Symptoms (4) · Carcinoma (3) · Mouth Diseases (3) · Neoplasms, Glandular and Epithelial (3)
Low-Level Light Therapy (9) · Standard of Care (7) · Petrolatum (5) · Norepinephrine (3) · Radiotherapy (3) · Sodium Chloride (3) · Biafine (2) · Curcumin (2) · Sodium Hypochlorite (2) · sapropterin (2) · triethanolamine (2) · Aloe vera gel (1) · Catechin (1) · Centella asiatica extract (1) · Dimethyl Sulfoxide (1)
West China Hospital (9) · Sunnybrook Health Sciences Centre (7) · Instituto Nacional de Cancer, Brazil (3) · Mayo Clinic (3) · ProCertus BioPharm, Inc (3) · Stratpharma AG (3) · University of Brasilia (3) · Wake Forest University Health Sciences (3) · AC Camargo Cancer Center (2) · AceTech (2) · China Medical University Hospital (2) · Hasselt University (2) · Institut Curie (2) · Jessa Hospital (2) · Montefiore Medical Center (2)
United States (31) · China (16) · Brazil (10) · Canada (9) · France (8) · Israel (7) · Egypt (6) · Belgium (4) · Italy (4) · Spain (3) · Taiwan (3) · Mexico (2) · Switzerland (2) · Australia (1) · Austria (1)
Xingchen Peng (5) · Edward LW Chow, MBBS (4) · Jeroen Mebis, MD, PhD (2) · Marcia A Ciol, PhD (2) · Mark Trombetta, MD (2) · Alina Markova, MD (1) · Amy Paller, MD (1) · Anke Bergmann, PhD (1) · Annelies Maes, MD (1) · Antonio J Conde Moreno (1) · Beth Beadle (1) · Beth McLellan, MD (1)
PMID 10443466, PMID 14566480, PMID 16893745, PMID 16980242, PMID 18474463, PMID 20118623, PMID 21153830, PMID 21694984, PMID 23825733, PMID 25141962, PMID 25525844, PMID 26328937, PMID 28596000, PMID 29273054, PMID 32450921, PMID 36493331, PMID 37140904, PMID 37441546, PMID 37819539, PMID 39292351, PMID 39316164, PMID 40259026, PMID 40973558, PMID 41642361, PMID 41861269
P30CA012197 (3), 2018 (2), 2023 (1), R21CA178648 (1), U10CA037420 (1), UG1CA189961 (1)