2 completed, 2 recruiting, 2 unknown, 1 active not recruiting. 8 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Completed 2, Recruiting 2, Unknown 2, Active not recruiting 1, Terminated 1 |
Follow Radiation Fibrosis Syndrome: new trials by email Literature Review of Radiation Fibrosis Syndrome trials Research Report on Radiation Fibrosis Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Losartan to Reduce Radiation Induced Fibrosis in Breast Cancer Patients Losartan 25 milligram capsule, Placebo - Radiation Induced Fibrosis | Phase 2 | Active not recruiting | Shaw Cancer Center | 43 | 2023-08-17 | 2026-06-18 |
| Evaluation of PET Probe [68Ga]CBP8 in the Detection of Radiation Induced Tissue Injury [68Ga]CBP8 - Lung Cancer, Radiation Fibrosis | Phase 2 | Recruiting | Massachusetts General Hospital | 72 | 2020-07-19 | 2026-02-27 |
| Prophylactic Inhaled Steroids to Reduce Radiation Pneumonitis Frequency and Severity in Lung Cancer Patients Inhaled budesonide - Radiation Pneumonitis | Phase 2 | Recruiting | Instituto Nacional de Cancerologia de Mexico | 72 | 2018-09-01 | 2026-04-08 |
| Clinical Study of Endostatin in Improving Radiation Pneumonia and Fibrosis Endostar, standard SRILI treatment - Radiation Pneumonitis, Endostatin | Phase 2 | Completed | Xinqiao Hospital of Chongqing | 126 | 2018-09-01 | 2024-02-23 |
| Image-Guided Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Shoulder, Arm, Hip, or Leg Chemotherapy, Radiation therapy, Surgery - Lymphedema, Musculoskeletal Complications | Phase 2 | Completed | Radiation Therapy Oncology Group | 98 | 2008-03-01 | 2019-06-12 |
| Hyperbaric Oxygen Therapy Compared With Standard Therapy in Treating Chronic Arm Lymphedema in Patients Who Have Undergone Radiation Therapy for Cancer hyperbaric oxygen - Breast Cancer, Lymphedema | Phase 2 | Unknown | Institute of Cancer Research, United Kingdom | 63 | 2004-04-01 | 2013-12-18 |
| Captopril in Treating Patients With Non-Small Cell Lung Cancer or Limited-Stage Small Cell Lung Cancer That Has Been Previously Treated With Radiation Therapy With or Without Chemotherapy captopril - Lung Cancer, Pulmonary Complications | Phase 2 | Terminated | Radiation Therapy Oncology Group | 81 | 2003-06-01 | 2018-03-08 |
| IH636 Grape Seed Extract in Treating Hardening of Breast Tissue in Women Who Have Undergone Radiation Therapy for Early Breast Cancer IH636 grape seed proanthocyanidin extract - Breast Cancer, Radiation Fibrosis | Phase 2 | Unknown | Royal Marsden NHS Foundation Trust | 2002-09-01 | 2013-11-06 |
Breast Neoplasms (3) · Carcinoma, Non-Small-Cell Lung (2) · Fibrosis (2) · Lung Neoplasms (2) · Lymphedema (2) · Radiation Pneumonitis (2) · Camurati-Engelmann Syndrome (1) · Chondrosarcoma, Extraskeletal Myxoid (1) · Inflammation (1) · Lung Diseases (1) · Lung Injury (1) · Pancreatic Neoplasms (1) · Postoperative Complications (1) · Radiation Injuries (1)
Pathologic Processes (8) · Pathological Conditions, Signs and Symptoms (8) · Wounds and Injuries (8) · Neoplasms (7) · Radiation Injuries (7) · Fibrosis (6) · Neoplasms by Site (6) · Respiratory Tract Diseases (4) · Breast Diseases (3) · Lung Diseases (3) · Skin Diseases (3) · Skin and Connective Tissue Diseases (3) · Bronchial Neoplasms (2) · Carcinoma, Bronchogenic (2) · Hemic and Lymphatic Diseases (2)
Captopril (1) · Drug Therapy (1) · Grape Seed Proanthocyanidins (1) · Hyperbaric Oxygenation (1) · Losartan (1) · Radiotherapy (1) · Surgical Procedures, Operative (1) · endostar protein (1)
Radiation Therapy Oncology Group (2) · Institute of Cancer Research, United Kingdom (1) · Instituto Nacional de Cancerologia de Mexico (1) · Massachusetts General Hospital (1) · Royal Marsden NHS Foundation Trust (1) · Shaw Cancer Center (1) · Xinqiao Hospital of Chongqing (1)
United States (4) · United Kingdom (2) · Canada (1) · China (1) · Mexico (1)
John R. Yarnold, MD, FRCR (2) · Burton L. Eisenberg, MD (1) · David G. Kirsch, MD, PhD (1) · Dian Wang, MD, PhD (1) · John M. Kane, MD (1) · Michael Lanuti, MD (1) · Oscar Arrieta, MD MSc (1) · Patricia H Hardenbergh, MD (1) · Scott Okuno, MD (1) · Shadi Esfahani, MD (1) · William Small, MD (1)
PMID 17050868, PMID 19962042, PMID 20583979, PMID 23909719, PMID 24459776, PMID 25276362, PMID 25667281, PMID 25808113, PMID 26830686, PMID 28477633, PMID 28596060, PMID 28865520, PMID 36995690, PMID 37808864, PMID 41014160
K08CA259626 (1), R44CA250771 (1)