3 completed. 3 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 3 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Pure Autonomic Failure: new trials by email Literature Review of Pure Autonomic Failure trials Research Report on Pure Autonomic Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Automated Abdominal Binder for Orthostatic Hypotension automated abdominal binder, Sham binder, Placebo - Orthostatic Hypotension, Autonomic Failure | Phase 1 / Phase 2 | Completed | Vanderbilt University Medical Center | 28 | 2018-03-01 | 2026-05-05 |
| TD-9855 Phase 2 in Neurogenic Orthostatic Hypotension (nOH) TD-9855, Placebo - Neurogenic Orthostatic Hypotension, Multiple System Atrophy (MSA) With Orthostatic Hypotension | Phase 2 | Completed | Theravance Biopharma | 34 | 2017-09-09 | 2022-09-26 |
| Evaluating the Effectiveness of Intravenous Immunoglobulin Therapy in Autoimmune Autonomic Ganglionopathy Double blinded IVIg, Double blinded Placebo, Single Blinded IVIg - Autoimmune Autonomic Ganglionopathy (AAG) | Phase 2 / Phase 3 | Completed | Beth Israel Deaconess Medical Center | 6 | 2012-02-01 | 2017-07-02 |
Hypotension, Orthostatic (3) · Multiple System Atrophy (2) · Autonomic Nervous System Diseases (1) · Multiple system atrophy (MSA) with orthostatic hypotension (1) · Parkinson Disease (1)
Cardiovascular Diseases (3) · Hypotension (3) · Nervous System Diseases (3) · Orthostatic Intolerance (3) · Primary Dysautonomias (3) · Vascular Diseases (3) · Autonomic Nervous System Diseases (2) · Basal Ganglia Diseases (2) · Brain Diseases (2) · Central Nervous System Diseases (2) · Movement Disorders (2) · Neurodegenerative Diseases (2) · Synucleinopathies (2) · Parkinsonian Disorders (1)
Immunoglobulins, Intravenous (1) · Midodrine (1) · ampreloxetine (1)
Beth Israel Deaconess Medical Center (1) · Theravance Biopharma (1) · Vanderbilt University Medical Center (1)
United States (3)
Italo Biaggioni, MD (1) · Luis E Okamoto, MD (1) · Roy Freeman, MD (1)
R01HL144568 (1), U54NS065736 (1)