13 completed, 6 unknown, 3 recruiting, 1 not yet recruiting. 17 Not applicable, 2 Phase 4, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 17 | Completed 8, Unknown 5, Recruiting 2, Not yet recruiting 1, Terminated 1 |
| Phase 4 | 2 | Completed 2 |
| Early Phase 1 | 1 | Recruiting 1 |
Follow Psychogenic Nonepileptic Seizures: new trials by email Literature Review of Psychogenic Nonepileptic Seizures trials Research Report on Psychogenic Nonepileptic Seizures
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cognitive Rehabilitation for Veterans With PNES Cognitive Rehabilitation And Functional Treatment (CRAFT) - Psychogenic Nonepileptic Seizures (PNES) | Not applicable | Recruiting | VA Office of Research and Development | 47 | 2026-03-02 | 2026-03-12 |
| Video-EEG Features of Adult Patients With Psychogenic Nonepileptic Seizures Psychogenic Nonepileptic Seizures | Completed | Saglik Bilimleri Universitesi | 50 | 2026-01-01 | 2026-04-13 | |
| Accelerated TMS for Seizure-Type Functional Neurologic Disorders Transcranial Magnetic Stimulation - Functional Neurological Symptom Disorder, Functional Seizures | Early Phase 1 | Recruiting | Medical University of South Carolina | 30 | 2025-09-02 | 2026-09-28 |
| The Feasibility and Acceptability of an Online Yoga Program for People With Functional Neurological Disorders A12 week, twice weekly, small group, online yoga program - Functional Neurological Disorder, Dissociative Seizures | Not applicable | Not yet recruiting | Nottingham University Hospitals NHS Trust | 30 | 2025-08-01 | 2025-07-22 |
| Evaluation of the Effect of a Single Dose of Psilocybin on Neural Correlates of Cognitive Control in Patients With Psychogenic Nonepileptic Seizures Psilocybin, MRI - Psychogenic Nonepileptic Seizures, Psilocybin | Not applicable | Completed | Centre Hospitalier Universitaire de Nīmes | 4 | 2024-12-19 | 2025-08-21 |
| Assessing the Impact of Brief CBTi on Dissociative Seizures: SCED brief Cognitive Behavioural Therapy for Insomnia (bCBTi) - Dissociative Seizures, Functional Seizures | Not applicable | Completed | University of Glasgow | 3 | 2024-05-06 | 2025-04-03 |
| A Multi-site Feasibility Clinical Trial of Retraining and Control Therapy (ReACT), a Mind and Body Treatment for Pediatric Functional Seizures ReACT, CATCH-IT - Functional Seizures, Convulsion, Non-Epileptic | Not applicable | Recruiting | University of Alabama at Birmingham | 108 | 2024-03-18 | 2026-03-17 |
| ADIE-FS - Aligning Dimensions of Interoceptive Experience in Patients With Functional Seizures Interoceptive training - Psychogenic Nonepileptic Seizures, Dissociative Seizures | Not applicable | Unknown | University College, London | 20 | 2024-01-10 | 2024-03-04 |
| TMS vs Conventional Therapy for the Treatment of Functional Neurological Non Epileptic Seizure Disorder Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation coil - Psychogenic Non-Epileptic Seizure | Not applicable | Completed | El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez | 28 | 2022-02-14 | 2023-09-28 |
| Self-modulation of the Sense of Agency by Means of Real-time Neurofeedback Real Neurofeedback, Sham Neurofeedback - Psychogenic Seizure, Epilepsy, Temporal Lobe | Not applicable | Unknown | ETH Zurich | 225 | 2022-02-01 | 2022-04-01 |
| Neurovegetative Decoupling in Somatoform Disorders : Biofeedback Interest Heart rate variability Biofeedback [HRV-BFB] - Somatoform Disorders, Irritable Bowel Syndrome | Not applicable | Terminated | University Hospital, Grenoble | 46 | 2021-03-16 | 2024-12-10 |
| Treatment for Psychogenic Nonepileptic Seizures and Post-traumatic Stress Disorder Using Prolonged Exposure Therapy (PE) or Psychoeducation for PNES imaginal and in vivo exposure, psychoeducation for psychogenic nonepileptic seizures - Psychogenic Nonepileptic Seizures (PNESs), Post Traumatic Stress Disorder PTSD | Not applicable | Completed | Northeast Regional Epilepsy Group | 44 | 2020-11-16 | 2026-01-16 |
| Project UPLIFT for Psychogenic Non-Epileptic Seizures Project UPLIFT - Psychogenic Non-Epileptic Seizure, Depression | Not applicable | Completed | Dartmouth-Hitchcock Medical Center | 8 | 2018-07-23 | 2021-09-28 |
| Mainz Epilepsy Registry no interventions, only observation - Epilepsy, Dissociative Seizures | Unknown | Johannes Gutenberg University Mainz | 700 | 2018-02-01 | 2022-03-04 | |
| Detecting PNES With Single-channel sEMG SPEAC System, video EEG - Epilepsy, Motor Partial, Psychogenic Seizures | Not applicable | Unknown | Brain Sentinel | 71 | 2017-11-03 | 2019-12-20 |
| Neuroimaging Biomarkers of Prognosis in Motor Functional Neurological Disorders Standard of Care - Conversion Disorder | Completed | Massachusetts General Hospital | 30 | 2017-09-01 | 2023-08-29 | |
| Quality of Life and Psychogenic Nonepileptic Seizures. Psychogenic Nonepileptic Seizures (PNESs) | Completed | University Hospital, Bordeaux | 72 | 2016-08-26 | 2022-05-13 | |
| Treating Non-epileptic Seizures Using Magnetic Brain Stimulation MagStim Rapid2 Transcranial Magnetic Simulation - Nonepileptic Seizures | Not applicable | Completed | University of Manitoba | 10 | 2016-06-01 | 2020-09-30 |
| Stress and Seizures - Can a Brief Self-help Book Help? Self-help booklet - Epilepsy, Dissociative Seizures | Not applicable | Completed | Sheffield Teaching Hospitals NHS Foundation Trust | 82 | 2014-11-01 | 2016-05-16 |
| Comparing Different Treatments in Reducing Dissociative Seizure Occurrence Cognitive Behavioral Therapy, Standardized Medical Care - Convulsion, Nonepileptic, Conversion Disorder | Not applicable | Completed | King's College London | 368 | 2014-10-01 | 2020-10-09 |
Showing 20 of 24. Sign in to see all of them.
Seizures (10) · Conversion Disorder (9) · Dissociative Disorders (4) · Epilepsy (4) · Depression (3) · Stress Disorders, Post-Traumatic (2) · Anxiety Disorders (1) · Combat Disorders (1) · Epilepsy, Partial, Motor (1) · Epilepsy, Temporal Lobe (1) · Irritable Bowel Syndrome (1) · Psychological Well-Being (1) · Sleep Initiation and Maintenance Disorders (1) · Sleep Wake Disorders (1)
Nervous System Diseases (24) · Neurologic Manifestations (24) · Pathological Conditions, Signs and Symptoms (24) · Signs and Symptoms (24) · Seizures (14) · Mental Disorders (13) · Somatoform Disorders (9) · Brain Diseases (6) · Central Nervous System Diseases (6) · Behavior (4) · Behavioral Symptoms (3) · Stress Disorders, Traumatic (3) · Trauma and Stressor Related Disorders (3) · Epilepsies, Partial (2) · Epilepsy (2)
Standard of Care (3) · Cognitive Behavioral Therapy (2) · Sertraline (2) · Transcranial Magnetic Stimulation (2) · Cognitive Training (1) · Psilocybin (1) · Therapeutics (1)
Rhode Island Hospital (2) · Brain Sentinel (1) · Central Hospital, Nancy, France (1) · Centre Hospitalier Universitaire de Nīmes (1) · Dartmouth-Hitchcock Medical Center (1) · ETH Zurich (1) · El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez (1) · Johannes Gutenberg University Mainz (1) · King's College London (1) · Massachusetts General Hospital (1) · Medical University of South Carolina (1) · Northeast Regional Epilepsy Group (1) · Nottingham University Hospitals NHS Trust (1) · Saglik Bilimleri Universitesi (1) · Sheffield Teaching Hospitals NHS Foundation Trust (1)
United States (9) · United Kingdom (5) · France (4) · Germany (1) · Mexico (1) · Switzerland (1) · Turkey (Türkiye) (1)
W. Curt LaFrance, Jr., MD, MPH (2) · Aatif Husain, MD (1) · Alan Towne, MD (1) · David Chen, MD (1) · Dr Jessica Fish, BSc, PhD, DClinPsy (1) · John Mellers (1) · Joseph Chasen, DO (1) · Laura Goldstein (1) · Laura H Goldstein, PhD MPhil (1) · Lindsay Schommer, APRN (1) · Lorna Myers, Ph.D. (1)
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1IK2RD000605-01A2 (1), K23NS045902 (1), R01AT012101 (1)