28 completed, 7 unknown, 6 terminated, 4 withdrawn. 47 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 47 | Completed 28, Unknown 7, Terminated 6, Withdrawn 4, Not yet recruiting 2 |
Follow Prolapse: new trials by email Literature Review of Prolapse trials Research Report on Prolapse
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Suzetrigine for Opioid-Sparing Postoperative Analgesia Following Transvaginal Pelvic Reconstructive Surgery Suzetrigine, Opioid Analgesics (Tramadol or Oxycodone), Scheduled Acetaminophen and Ibuprofen - Pelvic Organ Prolapse (POP), Stress Urinary Incontinence (SUI) | Phase 4 | Not yet recruiting | University of California, Los Angeles | 120 | 2026-11-01 | 2026-09-15 |
| Suzetrigine Following Urogynecologic Surgery: Investigation of Postoperative Pain Management Suzetrigine, Placebo - Pelvic Organ Prolapse (POP), Postoperative Pain | Phase 4 | Not yet recruiting | Aditi Talkad | 48 | 2026-11-01 | 2026-10-02 |
| Tranexamic Acid in Vaginal Reconstructive Surgery Tranexamic acid, Vasopressin, NaCl 0.9% - Pelvic Organ Prolapse | Phase 4 | Withdrawn | The University of Texas Medical Branch, Galveston | 2024-07-01 | 2025-01-31 | |
| Pre-operative Polyethylene Glycol 3350 for Minimally Invasive Urogynecologic Surgery Polyethylene Glycol 3350 - Constipation, Surgical Procedure, Unspecified | Phase 4 | Completed | University Hospitals Cleveland Medical Center | 72 | 2024-06-05 | 2026-09-22 |
| Intraperitoneal Bupivacaine for Pelvic Organ Prolapse Bupivacaine, Saline - Pelvic Organ Prolapse | Phase 4 | Completed | Indiana University | 91 | 2023-08-16 | 2025-04-20 |
| Preoperative Gabapentin vs Placebo for Vaginal Prolapse Surgery Gabapentin, Gabapentin Placebo - Pelvic Organ Prolapse, Perioperative/Postoperative Complications | Phase 4 | Completed | Joseph Kowalski | 110 | 2023-01-01 | 2025-08-12 |
| Axis(TM) Solvent-dehydrate Dermal Allograft in the Treatment of Pelvic Organ Prolapse. Axis Dermis biologic mesh repair for pelvic organ prolapse - Pelvic Organ Prolapse | Phase 4 | Unknown | Michigan Institution of Women's Health PC | 50 | 2021-11-02 | 2024-02-16 |
| BOTOX® at the Time of Prolapse Surgery for OAB OnabotulinumtoxinA 100 UNT, Injectable saline - Urinary Bladder, Overactive, Pelvic Organ Prolapse | Phase 4 | Unknown | Walter Reed National Military Medical Center | 138 | 2021-09-23 | 2021-10-14 |
| Sprix for Postoperative Pain Control Following Gynecologic Surgery Sprix - Post Operative Pain Control, Narcotic Use | Phase 4 | Withdrawn | University of Louisville | 2021-01-01 | 2022-07-29 | |
| Surgical Intervention With DermaPure vs Native Tissue in Pelvic Organ Prolapse DermaPure®, native tissue - Pelvic Organ Prolapse | Phase 4 | Unknown | Colorado Pelvic Floor Consultants | 50 | 2020-04-05 | 2020-01-23 |
| Lessons on Urethral Lidocaine in Urodynamics Water-Based Vaginal Lubricant, lidocaine topical - Urethra Issue, Pelvic Organ Prolapse | Phase 4 | Completed | University of Texas Southwestern Medical Center | 63 | 2019-08-14 | 2023-08-01 |
| The Effect of Local Analgesia on Postoperative Gluteal Pain in Patients Undergoing Sacrospinous Ligament Fixation marcaine and kenalog - Postoperative Pain, Pelvic Organ Prolapse | Phase 4 | Withdrawn | Kettering Health Network | 2019-02-02 | 2025-02-05 | |
| Pudendal Block Using Liposomal Bupivacaine vs. Standard Treatment During Sacrospinous Ligament Fixation Liposomal Bupivacaine - Vaginal Prolapse | Phase 4 | Unknown | Atlantic Health System | 88 | 2018-09-24 | 2021-05-10 |
| Nitrofurantoin Administration for the Prevention of Short-Term Catheter Associated Urinary Tract Infection After Pelvic Surgery Nitrofurantoin 100 MG, Placebo Oral Tablet - Catheter-Associated Urinary Tract Infection | Phase 4 | Completed | Wake Forest University Health Sciences | 164 | 2017-09-29 | 2022-08-09 |
| Gabapentin for Postop Pain After SSLF Gabapentin, Placebo oral capsule - Pelvic Organ Prolapse | Phase 4 | Completed | University of North Carolina, Chapel Hill | 45 | 2017-06-01 | 2020-10-26 |
| Ice T Postoperative Multimodal Pain Regimen in FPMRS Surgery Ice T, Motrin/Percocet/Dilaudid for breakthrough - Pain, Postoperative, Pelvic Organ Prolapse | Phase 4 | Completed | University Hospitals Cleveland Medical Center | 66 | 2017-04-01 | 2023-05-19 |
| Preoperative Oestrogen in Postmenopausal Women With Pelvic Organ Prolapse Linoladiol Estradiol, Placebo vaginal cream - Pelvic Organ Prolapse | Phase 4 | Completed | Medical University of Vienna | 120 | 2017-02-02 | 2020-11-17 |
| Deep Versus Moderate Neuromuscular Blockade During Laparoscopic Surgery Deep to Moderate NMB, Moderate to Deep NMB, Rocuronium - Cholecystitis, Endometriosis | Phase 4 | Completed | Stony Brook University | 79 | 2016-12-27 | 2020-04-08 |
| Investigation to Minimize Prolapse Recurrence of the Vagina Using Estrogen Conjugated Estrogens Cream, Placebo Cream - Pelvic Organ Prolapse, Urogenital Prolapse | Phase 4 | Completed | University of Texas Southwestern Medical Center | 206 | 2016-12-01 | 2023-09-06 |
| Vaginal Estriol Before and Vaginal Surgery for Prolapse estriol, vaginal surgery - Genital Prolapse | Phase 4 | Unknown | Salvatore Caruso | 88 | 2016-11-01 | 2016-09-19 |
Showing 20 of 47. Sign in to see all of them.
Pelvic Organ Prolapse (33) · Uterine Prolapse (11) · Cystocele (7) · Pain, Postoperative (7) · Urinary Incontinence (4) · Pelvic Floor Disorders (3) · Rectal Prolapse (3) · Urinary Incontinence, Stress (3) · Anastomotic Leak (1) · Atrophic Vaginitis (1) · Cholecystitis (1) · Colonic Neoplasms (1) · Constipation (1) · Diverticulitis (1)
Pathological Conditions, Anatomical (47) · Pathological Conditions, Signs and Symptoms (47) · Female Urogenital Diseases (21) · Female Urogenital Diseases and Pregnancy Complications (21) · Urogenital Diseases (21) · Male Urogenital Diseases (15) · Signs and Symptoms (15) · Genital Diseases (13) · Genital Diseases, Female (13) · Urologic Diseases (13) · Uterine Diseases (12) · Pelvic Organ Prolapse (11) · Pathologic Processes (10) · Lower Urinary Tract Symptoms (8)
Bupivacaine (3) · Estriol (2) · Estrogens, Conjugated (USP) (2) · Gabapentin (2) · Ibuprofen (2) · Nitrofurantoin (2) · Saline Solution (2) · Sodium Chloride (2) · Surgical Procedures, Operative (2) · Acetaminophen (1) · Analgesics, Opioid (1) · Arginine Vasopressin (1) · Cathartics (1) · Control Groups (1) · Ketorolac (1)
Halina M Zyczynski, MD (3) · University of Texas Southwestern Medical Center (3) · ASTORA Women's Health (2) · Federal University of São Paulo (2) · Medstar Health Research Institute (2) · The University of Texas Medical Branch, Galveston (2) · University Hospitals Cleveland Medical Center (2) · University Magna Graecia (2) · Aditi Talkad (1) · Atlantic Health System (1) · Boston Scientific Corporation (1) · Centre Hospitalier Universitaire de Nīmes (1) · Colorado Pelvic Floor Consultants (1) · Emanuel Trabuco (1) · Ethicon, Inc. (1)
United States (30) · Italy (3) · Brazil (2) · Denmark (2) · Austria (1) · Finland (1) · France (1) · Germany (1) · Norway (1) · Sweden (1) · Switzerland (1) · Taiwan (1)
Eric R Sokol, MD (2) · Fulvio Zullo, MD (2) · Stefano Palomba, MD (2) · A Lenore Ackeman, MD, PhD (1) · Amanda White, MD (1) · Andrew I Sokol, MD (1) · Ann Tran, MD (1) · Antonio Cianci, Prof (1) · Billy B Kristensen, MD (1) · Christian Falconer, MD, Assoc. prof. (1) · Christina M Hegan, APRN WHNP-BC (1) · Daniel Altman, MD, Assoc. prof. (1) · David D Rahn, MD (1) · David Sheyn, MD (1) · Dina Bastawros, MD (1)
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