5 recruiting, 2 enrolling by invitation, 1 active not recruiting. 5 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Recruiting 3, Enrolling by invitation 2 |
Follow Primary Progressive Aphasia(PPA): new trials by email Literature Review of Primary Progressive Aphasia(PPA) trials Research Report on Primary Progressive Aphasia(PPA)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Targeted Transcranial Magnetic Stimulation to Improve Language and Speech in Patients With Primary Progressive Aphasia Training with Speech Language Therapy, Standard rTMS, Targeted rTMS - Primary Progressive Aphasia(PPA) | Not applicable | Enrolling by invitation | IRCCS San Raffaele | 75 | 2026-05-13 | 2026-05-20 |
| Remotely-supervised Neuromodulation in PPA Lexical Retrieval Cascade Treatment, Remotely Supervised Transcranial Direct Current Stimulation- Active, Remotely Supervised Transcranial Direct Current Stimulation - Sham - Primary Progressive Aphasia(PPA), Progressive Aphasia | Not applicable | Recruiting | Maya Henry | 80 | 2026-04-15 | 2026-09-04 |
| Intervention for Communication Quality of Life in Primary Progressive Aphasia Multicomponent Lexical Retrieval Cascade Training, Multicomponent Video Implemented Script Training in Aphasia - Primary Progressive Aphasia(PPA), Semantic Dementia | Not applicable | Recruiting | Maya Henry | 30 | 2026-04-01 | 2026-04-21 |
| Long Term Effect of Brain Stimulation in PPA TMS, tDCS, Sham TMS - Primary Progressive Aphasia(PPA) | Not applicable | Recruiting | Hospital San Carlos, Madrid | 80 | 2025-09-15 | 2026-04-23 |
| Speech and Language Interventions for Italian People With PPA Behavioral Treatment - Primary Progressive Aphasia(PPA) | Recruiting | Istituti Clinici Scientifici Maugeri SpA | 30 | 2024-09-01 | 2026-10-26 | |
| Neuroinflammation in FTLD 7T MRI scan, CSF, Blood withdrawal - Corticobasal Syndrome(CBS), Primary Progressive Aphasia(PPA) | Active not recruiting | Leiden University Medical Center | 110 | 2023-07-25 | 2025-09-11 | |
| UPenn Observational Research Repository on Neurodegenerative Disease No intervention - Frontotemporal Degeneration(FTD), Primary Progressive Aphasia(PPA) | Recruiting | University of Pennsylvania | 1000 | 2020-05-29 | 2026-01-22 | |
| Tracking and Predicting How Brain Damage Spreads in Neurodegenerative Diseases 3 Tesla MRI without contrast medium, Blood sample for genetic analysis, Cerebrospinal fluid sampling (CSF) - Neurodegenerative Disease, Behavioral Variant Frontotemporal Dementia (bvFTD) | Not applicable | Enrolling by invitation | IRCCS San Raffaele | 645 | 2017-06-01 | 2026-05-05 |
Aphasia, Primary Progressive (8) · Frontotemporal Dementia (3) · Neurodegenerative Diseases (3) · Supranuclear Palsy, Progressive (3) · Amyotrophic Lateral Sclerosis (2) · Aphasia (2) · Communication Disorders (2) · Corticobasal Degeneration (2) · Alzheimer Disease (1) · Dementia (1) · Frontotemporal Lobar Degeneration (1) · Lewy Body Disease (1) · Nerve Degeneration (1) · Neuroinflammatory Diseases (1) · Primary Progressive Nonfluent Aphasia (1)
Brain Diseases (8) · Central Nervous System Diseases (8) · Language Disorders (8) · Mental Disorders (8) · Nervous System Diseases (8) · Neurobehavioral Manifestations (8) · Neurocognitive Disorders (8) · Neurologic Manifestations (8) · Pathological Conditions, Signs and Symptoms (8) · Signs and Symptoms (8) · Speech Disorders (8) · Dementia (7) · Aphasia (6) · Communication Disorders (6) · Metabolic Diseases (6)
Speech Therapy (2) · Behavior Therapy (1) · Blood Specimen Collection (1) · Genetic Testing (1) · Transcranial Direct Current Stimulation (1)
IRCCS San Raffaele (2) · Maya Henry (2) · Hospital San Carlos, Madrid (1) · Istituti Clinici Scientifici Maugeri SpA (1) · Leiden University Medical Center (1) · University of Pennsylvania (1)
Italy (3) · United States (3) · Netherlands (1) · Spain (1)
Maya L Henry, PhD (2) · David Irwin, MD (1) · Jessica D Richardson, PhD (1) · Prof. Massimo Filippi (1) · Prof.Massimo Filippi (1) · Stephanie M Grasso, PhD (1)
P01AG066597 (1), R01AG054519 (1), RF1AG085565 (1)