10 completed, 4 recruiting, 3 terminated, 1 enrolling by invitation. 11 Not applicable, 5 Phase 4, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 7, Recruiting 3, Terminated 1 |
| Phase 4 | 5 | Completed 2, Recruiting 1, Terminated 1, Unknown 1 |
| Phase 3 | 2 | Completed 1, Terminated 1 |
Follow Postpartum Preeclampsia: new trials by email Literature Review of Postpartum Preeclampsia trials Research Report on Postpartum Preeclampsia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nifedipine and Enalapril vs Nifedipine and Labetalol for the Treatment of Postpartum Hypertension Study Nifedipine and Enalapril, Nifedipine and Labetalol - Hypertension, Postpartum Preeclampsia | Not applicable | Recruiting | The Cleveland Clinic | 200 | 2026-03-10 | 2026-08-03 |
| Postpartum Preeclampsia Early Detection and Treatment: Nepal Pilot Study Early detection and management of postpartum preeclampsia bundle - Postpartum Preeclampsia | Not applicable | Recruiting | Medical College of Wisconsin | 60 | 2026-03-03 | 2026-07-20 |
| Rhode Island - Statewide Postpartum Hypertension Remote Surveillance RI-SPHERES, Standard self-measured blood pressure program - Hypertension in Pregnancy, Postpartum Preeclampsia | Not applicable | Recruiting | Women and Infants Hospital of Rhode Island | 1536 | 2025-04-15 | 2025-06-17 |
| Wearables to Define Postpartum Blood Pressure Trajectories and Facilitate Evidence-based Monitoring Guidelines BP Watch - Hypertension, Pregnancy-Induced, Hypertension | Enrolling by invitation | University of California, San Diego | 300 | 2024-10-24 | 2025-11-04 | |
| Postpartum Video Education in High Risk Populations Video Education - Postpartum Hemorrhage, Postpartum Depression | Not applicable | Terminated | Weill Medical College of Cornell University | 50 | 2024-05-09 | 2026-08-21 |
| Comprehensive Postpartum Management for Women With Hypertensive Disorders of Pregnancy Blood Pressure Control Targets, Hypertension Management - Hypertension, Pregnancy-Induced, Postpartum Preeclampsia | Not applicable | Completed | Vanderbilt University Medical Center | 343 | 2023-05-08 | 2026-03-12 |
| Management of Postpartum Preeclampsia Tight postpartum blood pressure control - Postpartum Preeclampsia | Not applicable | Completed | Rutgers, The State University of New Jersey | 392 | 2023-03-28 | 2024-04-02 |
| Postpartum Video Education Video Education - Postpartum Hemorrhage, Postpartum Preeclampsia | Not applicable | Completed | Yale University | 200 | 2022-07-05 | 2023-02-01 |
| Postpartum Hypertension Study Labetalol, Nifedipine - Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia | Phase 4 | Terminated | Columbia University | 2 | 2022-07-04 | 2026-05-06 |
| Labetalol or Nifedipine for Control of Postpartum Hypertension: A Randomized Controlled Trial Labetalol Oral Tablet, NIFEdipine ER - Postpartum Preeclampsia, Hypertension in Pregnancy | Phase 4 | Recruiting | Nebraska Methodist Health System | 600 | 2022-06-20 | 2024-04-12 |
| Lasix for the Prevention of De Novo Postpartum Hypertension Furosemide, Placebo - Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia | Phase 3 | Completed | Columbia University | 82 | 2021-10-20 | 2024-12-13 |
| Oral Combined Hydrochlorothiazide/Lisinopril Versus Oral Nifedipine for Postpartum Hypertension ACE Inhibitors and Diuretics, NIFEdipine ER - Hypertension in Pregnancy, Postpartum Preeclampsia | Phase 4 | Completed | The University of Texas Health Science Center, Houston | 70 | 2021-10-18 | 2025-11-10 |
| Assessment of Postpartum Education to Improve Compliance Education provided via a video format - Hypertension in Pregnancy, Postpartum Preeclampsia | Not applicable | Completed | Medstar Health Research Institute | 46 | 2020-09-14 | 2022-03-21 |
| Comparing Nifedipine and Enalapril in Medical Resources Used in the Postpartum Period NIFEdipine ER, Enalapril - Hypertension in Pregnancy, Preeclampsia Severe | Phase 4 | Completed | Brigham and Women's Hospital | 94 | 2020-01-24 | 2022-11-30 |
| Heart Health 4 New Moms: A Randomized Trial in the First Year After Preeclampsia Home Blood Pressure Monitoring, Heart Health 4 New Moms, Usual care - Preeclampsia, Gestational Hypertension | Not applicable | Completed | University of Pittsburgh | 148 | 2019-01-26 | 2021-12-03 |
| Innovation in Postpartum Care for Women With Hypertensive Disorders of Pregnancy At-home Blood Pressure Monitoring - Hypertension in Pregnancy, Hypertension, Pregnancy-Induced | Not applicable | Completed | University of North Carolina, Chapel Hill | 100 | 2018-09-01 | 2020-03-13 |
| Oral Nifedipine Versus Labetalol in Treatment of Postpartum Hypertension Oral Tablet - Postpartum Preeclampsia | Phase 4 | Unknown | Hossam Ahmed Abd Ellah | 100 | 2018-01-19 | 2018-04-04 |
| Postpartum Management of Hypertension in Pregnancy With Hydrochlorothiazide Hydrochlorothiazide 50mg Tablet, Placebo Tablet - Pre-Eclampsia, Gestational Hypertension | Phase 3 | Terminated | The University of Texas Medical Branch, Galveston | 453 | 2017-11-21 | 2026-07-14 |
| Efficacy of Diltiazem for the Control of Blood Pressure in Puerperal Patients With Severe Preeclampsia Diltiazem - Postpartum Preeclampsia | Not applicable | Completed | Hospital de la Mujer | 42 | 2009-01-01 | 2020-01-10 |
Hypertension, Pregnancy-Induced (11) · Hypertension (8) · Pre-Eclampsia (5) · Depression, Postpartum (2) · Patient Participation (2) · Postpartum Hemorrhage (2) · Puerperal Infection (2) · Cardiovascular Diseases (1) · Hypertensive Crisis (1) · Obesity (1) · Overweight (1) · Pregnancy Complications (1)
Female Urogenital Diseases and Pregnancy Complications (15) · Urogenital Diseases (15) · Pregnancy Complications (14) · Vascular Diseases (14) · Cardiovascular Diseases (13) · Hypertension (6) · Pathological Conditions, Signs and Symptoms (3) · Behavior (2) · Depressive Disorder (2) · Health Behavior (2) · Hemorrhage (2) · Hypertension, Pregnancy-Induced (2) · Infections (2) · Mental Disorders (2) · Mood Disorders (2)
Labetalol (3) · Nifedipine (3) · Enalapril (2) · Tablets (2) · Angiotensin-Converting Enzyme Inhibitors (1) · Blood Pressure Monitors (1) · Diltiazem (1) · Diuretics (1) · Enalaprilat (1) · Furosemide (1) · Hydrochlorothiazide (1) · Sugars (1)
Columbia University (2) · Brigham and Women's Hospital (1) · Hospital de la Mujer (1) · Hossam Ahmed Abd Ellah (1) · Medical College of Wisconsin (1) · Medstar Health Research Institute (1) · Nebraska Methodist Health System (1) · Rutgers, The State University of New Jersey (1) · The Cleveland Clinic (1) · The University of Texas Health Science Center, Houston (1) · The University of Texas Medical Branch, Galveston (1) · University of California, San Diego (1) · University of North Carolina, Chapel Hill (1) · University of Pittsburgh (1) · Vanderbilt University Medical Center (1)
United States (17) · Egypt (1) · Nepal (1)
Alisse Hauspurg, MD (1) · Amol Malshe, M.D. (1) · Angelica Glover, MD (1) · Anna Palatnik, MD (1) · Benjamin Bush, M.D. (1) · Deepika Sagaram, MD (1) · Heather Lipkind, MD, MPH (1) · Heather Lipkind, MD, MSce (1) · Michal Fishel Bartal, MD (1) · Mohamed Mahmoud, Prof (1) · Russell S. Miller, MD (1) · Sara Iqbal, MD (1) · Sarah Osmundson, MD (1) · Thomas McElrath, MD, PhD (1) · Todd Lovgren, MD (1)
PMID 32774912, PMID 37708502, PMID 37806651, PMID 38073563, PMID 41139061, PMID 41999191