223 completed, 108 unknown, 42 terminated, 20 recruiting. 435 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 435 | Completed 223, Unknown 108, Terminated 42, Recruiting 20, Withdrawn 18, Not yet recruiting 13, Active not recruiting 6, Suspended 4, Enrolling by invitation 1 |
Follow Pneumonia: new trials by email Literature Review of Pneumonia trials Research Report on Pneumonia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The LalelaLung Study: Digital Stethoscope Clinical Evaluation StethoMe AI-enabled digital stethoscope system, Standard IMCI assessment - Pneumonia, Tuberculosis, Pulmonary | Phase 4 | Not yet recruiting | Johns Hopkins University | 350 | 2026-11-02 | 2026-09-23 |
| A Study to Investigate the Immunogenicity and Safety of mRNA COVID-19 Variant-containing Formulations mRNA-1273, mRNA-1283 - SARS-CoV-2 | Phase 4 | Recruiting | ModernaTX, Inc. | 300 | 2026-10-09 | 2026-10-27 |
| Tobramycin Nebulization to Prevent Multidrug-Resistant Ventilator-Associated Pneumonia Tobramycin inhalation solution, 0.9% Sodium Chloride Placebo - Pneumonia, Ventilator-Associated | Phase 4 | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 574 | 2026-10-07 | 2026-10-02 |
| Study of a Recombinant Spike COVID-19 Vaccine With Matrix-M in Older Adults and People at Increased Risk of Severe COVID-19 Omicron Subvariant-Based SARS-CoV-2 Recombinant Spike Vaccine Adjuvanted With Matrix-M - COVID-19 | Phase 4 | Recruiting | Sanofi | 660 | 2026-10-01 | 2026-10-15 |
| Oral Hygiene Assistance Training Program Stannous Fluoride Toothpaste (SnF), sodium fluoride 5000 ppm, cetylpyridinium chloride (0.075%) and zinc alcohol free mouthwash - Elderly, Periodontal Disease | Phase 4 | Not yet recruiting | Colgate Palmolive | 500 | 2026-09-20 | 2026-09-08 |
| Prevention of Infection of the Respiratory Tract Through Application of Non-Invasive Methods of Secretion Suctioning airway clearance, subglottic secretion aspiration, Ceftriaxone 2 grams daily - Intubation Complication, Stroke, Ischemic | Phase 4 | Not yet recruiting | Hospital San Carlos, Madrid | 60 | 2026-09-15 | 2026-08-06 |
| Ceftriaxone Dosage for Non-Critical Community-Acquired Pneumonia Ceftriaxone 1 gram daily, Ceftriaxone 2 grams daily - Community Acquired Pneumonia (CAP) | Phase 4 | Not yet recruiting | University of Maryland, Baltimore | 900 | 2026-09-01 | 2026-09-14 |
| Effectiveness of An Influenza/COVID-19 Vaccine (mCombriax [mRNA-1083]) in Adults ≥ 65 Years mCombriax® (mRNA-1083), Efluelda® (TIV-HD) and Spikevax® (mRNA-1273) - COVID-19, Influenza | Phase 4 | Not yet recruiting | Tor Biering-Sørensen | 410000 | 2026-09-01 | 2026-08-27 |
| A Study to Learn About a COVID-19 Vaccine in Healthy Adults 18 Through 64 Years of Age BNT162b2 Vaccine, Tdap Vaccine - COVID-19 Vaccines | Phase 4 | Recruiting | BioNTech SE | 200 | 2026-07-23 | 2026-08-07 |
| Health Economic Evaluation of Influenza and Pneumococcal Vaccination in COPD Patients Influenza Vaccine Group, Pneumococcal Vaccine Group - Influenza and Pneumonia | Phase 4 | Not yet recruiting | Jiangsu Province Centers for Disease Control and Prevention | 7000 | 2026-06-15 | 2026-06-11 |
| Low- vs Standard-Dose TMP-SMX for Prevention of Pneumocystis Pneumonia After Kidney Transplantation Trimethoprim-Sulfamethoxazole (TMP-SMX) - Pneumocystis Jirovecii Pneumonia, Kidney Transplantation | Phase 4 | Not yet recruiting | Anhui Provincial Hospital | 1084 | 2026-06-01 | 2026-06-01 |
| Combined Use of a Respiratory Multiplex PCR and Algorithm-based Therapy to Improve Early Optimization of Antibiotic Therapy in Critically Ill Patients With Ventilator-associated Pneumonia strategy combining respiratory mPCR and algorithm-based therapy developed using local epidemiology - Ventilator Associated Pneumonia ( VAP) | Phase 4 | Recruiting | Centre Hospitalier Universitaire de Nīmes | 124 | 2026-03-27 | 2026-10-13 |
| Comparing Hydrocortisone and Prednisolone for Community Acquired Pneumonia (CAP) Methylprednisolone (drug), hydrocortisone - Community Acquired Pneumonia (CAP) | Phase 4 | Recruiting | Copenhagen Respiratory Research | 1600 | 2026-03-10 | 2026-03-18 |
| Positioning Second-line Therapies for Pneumocystis Jirovecii Pneumonia (PCP Alternatives) Clindamycin + primaquine, Pentamidine, Atovaquone - Pneumocystis, Pneumocystis Infection | Phase 4 | Not yet recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 416 | 2026-03-01 | 2026-01-21 |
| Doxycycline vs. Macrolide for MRMP (DOMINO) Doxycycline, Azithromycin - Mycoplasma Pneumoniae, Mycoplasma Pneumoniae Pneumonia | Phase 4 | Not yet recruiting | Young June Choe | 208 | 2026-03-01 | 2025-12-29 |
| Trial of Reducing Inpatient Antibiotic Durations in Children Study Drug Placebo - Pneumonia, Skin and Soft Tissue (SST) Infection | Phase 4 | Enrolling by invitation | University of California, San Francisco | 1200 | 2026-02-13 | 2026-04-29 |
| How Long Should we Give Steroids for Patients With Severe PCP Systemic corticosteroids - Pneumocystis Pneumonia, Pneumocystis | Phase 4 | Not yet recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 416 | 2026-01-30 | 2026-01-09 |
| Opportunistic Pneumococcal Immunisation Trial in MALnutrition Pneumococcal conjugate vaccine, Typhoid conjugate vaccine - Severe Acute Malnutrition in Childhood, Pneumococcal Disease | Phase 4 | Recruiting | Nick Fancourt | 214 | 2026-01-16 | 2026-10-08 |
| Oral Hygiene and Prophylactic Antibiotics to Prevent Intracerebral Hemorrhage Associated Pneumonia wether apply enhanced oral care combined with prophylactic antibiotics - Hemorrhage, Pneumonia | Phase 4 | Recruiting | Beijing Tiantan Hospital | 440 | 2026-01-07 | 2026-02-12 |
| Effectiveness of mRNA-1273 Variant-Containing Vaccine Formulation Against Severe Outcomes in Adults Aged 50-64 Years Without Risk Factors for Severe COVID-19 mRNA-1273 (Moderna COVID-19 vaccine) - COVID-19 | Phase 4 | Completed | Tor Biering-Sørensen | 41060 | 2025-12-11 | 2026-10-06 |
Showing 20 of 435. Sign in to see all of them.
COVID-19 (242) · Pneumonia, Ventilator-Associated (37) · Community-Acquired Pneumonia (35) · Coronavirus Infections (29) · Infections (16) · Influenza, Human (16) · Pneumonia, Pneumococcal (11) · Pulmonary Disease, Chronic Obstructive (11) · Respiratory Tract Infections (11) · Healthcare-Associated Pneumonia (10) · Pneumonia, Bacterial (9) · Pneumonia, Pneumocystis (9) · Post-Acute COVID-19 Syndrome (9) · Diarrhea (8)
Respiratory Tract Diseases (431) · Respiratory Tract Infections (424) · Infections (419) · Lung Diseases (407) · RNA Virus Infections (257) · Virus Diseases (255) · Coronaviridae Infections (245) · Nidovirales Infections (245) · Pneumonia, Viral (242) · Coronavirus Infections (218) · Pathological Conditions, Signs and Symptoms (109) · Pathologic Processes (92) · Disease Attributes (72) · Bacterial Infections and Mycoses (47)
sinovac COVID-19 vaccine (19) · Hydroxychloroquine (17) · Azithromycin (16) · 2019-nCoV Vaccine mRNA-1273 (15) · BNT162 Vaccine (15) · Amoxicillin (13) · Sodium Chloride (12) · Standard of Care (12) · Ceftriaxone (11) · Dexamethasone (10) · Levofloxacin (10) · Amoxicillin-Potassium Clavulanate Combination (9) · Pneumococcal Vaccines (9) · Enoxaparin (8) · Methylprednisolone (8)
China National Biotec Group Company Limited (12) · Jiangsu Province Centers for Disease Control and Prevention (9) · Pfizer (9) · Sinovac Research and Development Co., Ltd. (9) · Sanofi (6) · Ain Shams University (5) · ClinAmygate (5) · National Institute of Allergy and Infectious Diseases (NIAID) (5) · ModernaTX, Inc. (4) · Shahid Beheshti University of Medical Sciences (4) · Sinovac Biotech Co., Ltd (4) · Sinovac Life Sciences Co., Ltd. (4) · Tor Biering-Sørensen (4) · Forest Laboratories (3) · Mayo Clinic (3)
United States (106) · China (66) · Spain (28) · Brazil (19) · Egypt (19) · Canada (15) · France (15) · Denmark (14) · Netherlands (12) · India (10) · Thailand (10) · Belgium (9) · United Kingdom (9) · Germany (8) · Pakistan (8)
Jing-Xin Li, PhD (5) · Hanqing He (4) · Seyed Sina Naghibi Irvani, MD, MPH, MBA (4) · Ruizhi Zhang (3) · Sutep Jaruratanasirikul, MD (3) · Aijaz Zeeshan Khan Chachar, MBBS,FCPS (2) · Amy Ginsburg, MD, MPH (2) · Avni Thakore, MD (2) · Dongjuan Zhang (2) · Emad R Issak, MD (2) · Fubing Wang (2) · George Sakoulas, MD (2) · Hongxing Pan, Master (2)
PMID 35244208, PMID 34473343, PMID 33502773, PMID 37591523, PMID 17872488, PMID 35012490, PMID 36658045, PMID 37489818, PMID 10404452, PMID 11225528, PMID 11296335, PMID 11505791, PMID 11778260, PMID 11888973, PMID 14998500, PMID 15867027, PMID 15917525, PMID 16236878, PMID 16444180, PMID 16490989, PMID 17029130, PMID 17090560, PMID 17099299, PMID 17604300, PMID 18545744, PMID 18707849, PMID 18719064, PMID 19234987, PMID 19433997, PMID 20354090, PMID 20686433, PMID 20729232, PMID 20843245, PMID 21396214, PMID 21458737, PMID 21478738, PMID 21684825, PMID 21723357, PMID 21829969, PMID 22078721, PMID 22285055, PMID 22384005, PMID 22403223, PMID 22422274, PMID 22483191, PMID 22805273, PMID 22888091, PMID 22952580, PMID 22997178, PMID 23017003
2025 (2), 1OT2HL156812-01 (1), 2014 (1), 2019 (1), R01HD038327 (1), R01HD079695 (1), R01MD016872 (1), R33HD109804 (1), R61HL183016 (1)