25 recruiting. 25 Phase 1, 14 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 25 | Recruiting 25 |
| Phase 2 | 14 | Recruiting 14 |
Follow Pneumonia: new trials by email Literature Review of Pneumonia trials Research Report on Pneumonia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MP101 in Adults With Acute Pseudomonas Aeruginosa Pneumonia MP101, Antibiotics - Pneumonia - Bacterial, Pseudomonas Aeruginosa Infection | Phase 1 | Recruiting | MicrobiotiX Co., Ltd | 18 | 2026-07-25 | 2026-07-28 |
| Development of a Controlled Human Infection Model for Assessment of SARS-CoV-2 Omicron Subvariants SARS-CoV-2 Omicron EG.5.1 challenge agent 10^5 TCID50, SARS-CoV-2 Omicron EG.5.1 challenge agent 10^6 TCID50, SARS-CoV-2 Omicron EG.5.1 challenge agent 10^4 TCID50 - SARS-CoV-2 (COVID-19) | Phase 1 | Recruiting | Imperial College London | 38 | 2026-07-10 | 2026-07-17 |
| A Study Evaluating MDX2301 in Healthy Adults and Adults at Higher Risk for Severe COVID-19. MDX2301, Normal Saline - COVID -19, COVID-19 (Prevention) | Phase 1 | Recruiting | ModeX Therapeutics, An OPKO Health Company | 80 | 2026-03-24 | 2026-09-10 |
| Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease Kisspeptin 112-121 - Reproductive Disorder, Neurodegeneration | Phase 1 | Recruiting | Stephanie B. Seminara, MD | 40 | 2026-03-10 | 2026-07-13 |
| A Study on the Safety and Immune Response of Investigational mRNA Seasonal Flu/COVID-19 Combination Vaccine in Adults Investigational mRNA Seasonal Flu/COVID-19 Combination (Flu/COVm) Vaccine, Licensed Seasonal Influenza Vaccine, Licensed COVID-19 Vaccine - Influenza, Human+COVID-19 | Phase 1 | Recruiting | GlaxoSmithKline | 225 | 2026-03-09 | 2026-06-30 |
| CaspoNEB: Efficacy and Safety of Caspofungin Aerosols for the Curative Treatment of Pneumocystis Pneumonia Caspofungin Acetate 50 MG, Physiologic saline - Pneumocystis Pneumonia, Pneumocystis Jirovecii Infection | Phase 1 / Phase 2 | Recruiting | University Hospital, Tours | 100 | 2025-12-02 | 2026-10-09 |
| A Phase 1/2A, Randomized Study of a T Follicular Helper (TFH)-Targeting Genetic Vaccine Strategy Designed to Induce Broad, Durable Immune Responses CoTend-BXBB (SARS2-30404), CoTend-s3BXBB (SARS2-17032), Placebo - COVID-19, SARS-CoV-2 Infection | Phase 1 / Phase 2 | Recruiting | Kara Chew | 80 | 2025-10-21 | 2026-08-18 |
| Study of S-892216 Long-acting Injectable (LAI) in Healthy Adult Participants S-892216-LAI, Placebo - Healthy Participants | Phase 1 | Recruiting | Shionogi | 128 | 2025-07-29 | 2026-10-16 |
| PET Imaging of Cyclooxygenase-1 in Participants With Neurological Manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC) 11C-PS13 - Long COVID, Post Acute Sequelae of COVID-19 | Phase 1 | Recruiting | National Institute of Mental Health (NIMH) | 60 | 2025-06-18 | 2026-08-18 |
| Study Comparing Safety and Immunogenicity of Intranasal COVID-19 Vaccine and mRNA Booster in Healthy Adults LVT-001, Cormirnaty - Healthy | Phase 1 / Phase 2 | Recruiting | ANRS, Emerging Infectious Diseases | 238 | 2025-05-09 | 2025-12-18 |
| The Role of Melatonin as an Adjuvant Therapy in Childhood Pneumonia Melatonin - Pneumonia Childhood | Phase 1 / Phase 2 | Recruiting | Mian Muhammad Hassan Ahmed | 60 | 2025-05-01 | 2025-04-29 |
| A Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Study to Evaluate the Safety and Efficacy of Uterine Blood Mesenchymal Stem Cells Injection for the Treatment of Severe Pneumonia Caused by Viruses Placebo, Drug therapy, Standard Treatment - Severe Viral Pneumonia(Not Include COVID-19) | Phase 1 | Recruiting | Ruijin Hospital | 60 | 2025-01-20 | 2024-12-27 |
| Medical Herbs Inhibit Inflammation Directing T Cells to Kill the COVID-19 Virus (COVID) Inflammation (I), Inflammation (II), Inflammation (III) - Covid19 Virus Infection | Phase 1 / Phase 2 | Recruiting | All Natural Medicine Clinic, LLC | 100 | 2025-01-01 | 2025-02-19 |
| Lumbrokinase for Adults With Long Covid, Post-treatment Lyme Disease Syndrome, and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Lumbrokinase - Long Covid, Post-treatment Lyme Disease Syndrome | Phase 1 / Phase 2 | Recruiting | Icahn School of Medicine at Mount Sinai | 120 | 2024-10-09 | 2026-03-13 |
| Study on Safety and Efficacy of Two Doses of PRS CK STORM in the Modulation of the Cytokine Storm in Patients With Acute Respiratory Infection Caused by SARS-Cov-2, Influenza A, Influenza B and Respiratory Syncytial Virus (RSV) Placebo comparator, PRS CK STORM - SARS-CoV-2, Influenza, Human | Phase 1 / Phase 2 | Recruiting | PEACHES BIOTECH | 50 | 2024-10-02 | 2026-06-10 |
| Safety and Immunogenicity of a Sub-unit Protein CD40.RBDv Bivalent COVID-19 Vaccine, Adjuvanted or Not, as a Booster in Volunteers. CD40.RBDv vaccin (SARS-Cov2 Vaccin) - COVID-19 | Phase 1 / Phase 2 | Recruiting | ANRS, Emerging Infectious Diseases | 215 | 2024-05-27 | 2025-04-25 |
| Covid-19 and Influenza Oral Vaccine Study Covid-19 vaccine, Influenza vaccine - covid19 Infection, Influenza, Human | Phase 1 | Recruiting | Vaxine Pty Ltd | 100 | 2024-05-01 | 2025-09-17 |
| Safety and Efficacy of MSC-EVs in the Prevention of BPD in Extremely Preterm Infants Endotracheopulmonary Instillation, Suspension - Bronchopulmonary Dysplasia | Phase 1 / Phase 2 | Recruiting | EXO Biologics S.A. | 265 | 2023-12-28 | 2024-09-19 |
| Single-cell Sequencing of BLF to Guide the Treatment of Radiation Pneumonitis or Immune Checkpoint Inhibitor Pneumonitis single-cell sequencing - Pneumonitis | Phase 1 / Phase 2 | Recruiting | Xinqiao Hospital of Chongqing | 40 | 2023-08-01 | 2025-07-14 |
| Cell Therapy With Treg Cells Obtained From Thymic Tissue (thyTreg) to Control the Immune Hyperactivation Associated With COVID-19 and/or Acute Respiratory Distress Syndrome (THYTECH2) Allogeneic thyTreg 5.000.000, Allogeneic thyTreg 10.000.000 - Systemic Inflammatory Response Syndrome | Phase 1 / Phase 2 | Recruiting | Hospital General Universitario Gregorio Marañon | 24 | 2023-06-27 | 2026-09-18 |
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COVID-19 (16) · Influenza, Human (3) · Post-Acute COVID-19 Syndrome (3) · Virus Diseases (3) · Infections (2) · Inflammation (2) · Lung Diseases (2) · Systemic Inflammatory Response Syndrome (2) · Thrombosis (2) · Alzheimer Disease (1) · Atrial Fibrillation (1) · Autoimmune Diseases (1) · Brain Diseases (1) · Bronchopulmonary Dysplasia (1)
Respiratory Tract Diseases (25) · Respiratory Tract Infections (25) · Infections (23) · Lung Diseases (23) · Coronaviridae Infections (19) · Nidovirales Infections (19) · Coronavirus Infections (18) · Pneumonia, Viral (18) · RNA Virus Infections (18) · Virus Diseases (16) · Pathologic Processes (9) · Pathological Conditions, Signs and Symptoms (9) · Bacterial Infections and Mycoses (3) · COVID-19 (3)
Saline Solution (2) · Standard of Care (2) · 11C-PS13 (1) · Anti-Bacterial Agents (1) · Blood Specimen Collection (1) · COVID-19 Vaccines (1) · CVnCoV COVID-19 vaccine (1) · Caspofungin (1) · Dosage Forms (1) · Drug Therapy (1) · Influenza Vaccines (1) · Melatonin (1) · Ritonavir (1) · Suspensions (1) · VIR-7832 (1)
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Beatrice De Vos, M.D., Ph.D. (1) · Christopher Chiu, BMBCh FRCP FRCPath PhD (1) · Ciprian Catana, PhD (1) · David Bernal, Dr. (1) · David Putrino, PhD, PT (1) · Dennis Hartigan-O'Connor, MD, PhD (1) · Dimitar Sajkov, MBBS/PhD (1) · Ernst R Von Schwarz, MD, PhD (1) · Jianguo Sun, doctor (1) · Jun Yong Choi (1)
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